Gamma-camera utilizing the interaction depth in a detector

• US 8,013,308 B2
• Filed: 10/20/2006
• Issued: 09/06/2011
• Est. Priority Date: 10/20/2006
• Status: Active Grant

• Current Assignee: Commissariat a L'Energie Atomique (AES Corporation)
• Original Assignee: Commissariat a L'Energie Atomique (AES Corporation)
• Inventors: Verger, Loïck, Rebuffel, Véronique, Guerin, Lucie
• Primary Examiner(s): Porta; David P
• Assistant Examiner(s): Kim; Kiho
• Application Number:
  US12/446,064
• Publication Number:
  US 20100038548A1
• Time in Patent Office: 1,782 Days
• Field of Search: 25037001-37015, 250/367, 250/363.02, 250/363.03, 250/369, 250/366, 600/407, 600/436, 378/98.8
• US Class Current: 250/370.09
• CPC Class Codes: G01T 1/242 Stacked detectors, e.g. for depth information constructional or manufacturing details H01L25/00
• CPC Class Codes: G01T 1/249 specially adapted for use in SPECT or PET SPECT imaging G01T1/1642; PET imaging G01T1/2985; detecting prohibited goods, e.g. weapons, explosives, hazardous substances, contraband or smuggled objects G01V5/20
• CPC Class Codes: G01T 1/2928 using solid state detectors

Abstract

A method for reconstructing an image of a source (S) of photons from interactions of photons emitted by this source with a detector (2) of a gamma-camera, positioned behind a collimator (4), the method including associating with each photon interaction with the detector, a piece of information relating to the depth in the detector, of this interaction, and reconstructing an image of the source (S) of photons from said depth information in the detector.

Claims

1. A method for reconstructing an image from a source (S) of photons, from interactions of photons emitted by this source, with a detector of a gamma-camera, positioned behind a collimator, comprising:

associating with each photon interaction with the detector, a piece of information relating to the depth in the detector, of this interaction,

reconstructing an image of the source (S) of photons from said depth information, the method further comprising breaking down the detector into several pixels, and each pixel into several superposed voxels, and further comprising, prior to the reconstruction step, the following steps;

determining for each received photon, the voxel of the detector in which the photon has interacted, and

counting for each voxel of the detector the number of photons having interacted in this voxel,

defining for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons, and

wherein the reconstruction step is implemented from said statistical data.

2. The method according to claim 1, wherein the detector is broken down into n interaction layers of identical thicknesses or having increasing thicknesses from the entry face of the detector, the voxels of a same pixel belonging to different layers.

3. The method according to claim 1, the volume of each portion of the detector located in the extension of each hole of the collimator, comprising at least two pixels.

4. The method according to claim 1, the information relating to the depth in the detector being obtained by determining the rise time and/or the amplitude of a signal measured at the terminals of the detector.

5. A method for reconstructing an image from a source (S) of photons, from interactions of photons emitted by this source, with a detector of a gamma-camera, positioned behind a collimator, comprising:

breaking down the detector into several pixels, and each pixel into several superposed voxels,

determining for each received photon, the voxel of the detector in which the photon has interacted,

counting for each voxel of the detector the number of photons having interacted in this voxel,

defining for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons, and

reconstructing an image of the source (S) of photons from said statistical data.

6. A method for reconstructing an image from a source (S) of photons, from interactions of photons emitted by this source, with a detector of a gamma-camera, positioned behind a collimator, comprising:

breaking down the detector into several pixels, and each pixel into several superposed voxels,

determining for each received photon, the voxel of the detector in which the photon has interacted,

counting for each voxel of the detector the number of photons having interacted in this voxel,

defining for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons, and

reconstructing an image of the source (S) of photons from said statistical data, said reconstructing implementing an iterative reconstruction method starting from a modeling connecting the detector and the image of the source to be reconstructed, defined by [p]=[R][f] wherein

[f] is a matrix comprising I terms fl to fI, the i^th term fi corresponding to a number of photons emitted by an i^th voxel of the source,

[p] is a matrix comprising K terms p1 to pK, K being equal to the number of voxels of the detector, the k^th term pk corresponding to the statistical datum determined for the k^th voxel of the detector, and

[R] is a matrix corresponding to a projection operator of [f] on [p].

7. The method according to claim 6, said reconstructing being carried out according to an algebraic iterative method.

8. The method according to claim 6, said reconstructing method being a statistical iterative method.

9. A device for reconstructing an image of a source of photons from interactions of photons, emitted by this source, with a detector of a gamma-camera positioned behind a collimator, this device including a microcomputer or an electronic circuit associating with each interaction of photon, emitted by a source of photons, with the detector, a piece of information relating to the depth in the detector of this interaction, and reconstructing an image of the source of photons from said depth information,

wherein the detector is broken down into several pixels, each pixel comprising several superposed voxels, and wherein said microcomputer or said electronic circuit:

determines, for each received photon, the voxel of the detector in which the photon has interacted,

counts, for each voxel of the detector, the number of photons having interacted in this voxel, and defines for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons,

reconstructs images from said statistical data.

10. The device according to claim 9, the detector comprising semiconducting material selected from the group consisting of CdZnTe and CdTe type.

11. An imaging device including:

a detector of a gamma-camera,

a collimator positioned in front of the detector,

and a microcomputer or an electronic circuit for reconstructing images of a source of photons from interactions of photons, emitted by this source, with said detector, said microcomputer or electronic circuit associating with each interaction of photon, emitted by said source of photons, with said detector, a piece of information relating to the depth in said detector of this interaction, and reconstructing an image of the source of photons from said depth information, wherein the detector is broken down into several pixels, each pixel comprising several superposed voxels, and wherein said microcomputer or said electronic circuit;

determines, for each received photon, the voxel of the detector in which the photon has interacted,

counts, for each voxel of the detector, the number of photons having interacted in this voxel, and defines for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons, and

reconstructs images from said statistical data.

12. An imaging device including:

a radiation detector of a gamma-camera, said detector being broken down into several pixels, each pixel comprising several superposed voxels, said detector being monolithic, the voxels of each pixel being defined by virtually breaking down the detector, each pixel being connected to a single anode/cathode set, with which the electric signals produced by a photon interaction in one of the voxels of the relevant pixel can be measured;

a collimator positioned in front of the detector,

and a microcomputer or an electronic circuit for reconstructing images of a source of photons from interactions of photons, emitted by this source, with said detector, said microcomputer or electronic circuit;

a) associating with each interaction of photon, emitted by said source of photons, with said detector, the voxel of the detector in which the photon has interacted, relating to the depth in said detector of this interaction,

b) counting, for each voxel of the detector, the number of photons having interacted in this voxel, and defining for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons,

c) reconstructing an image of the source of photons from said statistical data.

13. An imaging device including:

a radiation detector of a gamma-camera, said detector being broken down into several pixels, each pixel comprising several superposed voxels, each voxel of the detector being connected to an anode/cathode set, with which the electric signals produced by a photon interaction in the relevant voxel can be measured,

a collimator positioned in front of the detector,

and a microcomputer or an electronic circuit for reconstructing images of a source of photons from interactions of photons, emitted by this source, with said detector, said microcomputer or electronic circuit;

a) associating with each interaction of photon, emitted by said source of photons, with said detector, the voxel of the detector in which the photon has interacted, relating to the depth in said detector of this interaction,

b) counting, for each voxel of the detector, the number of photons having interacted in this voxel, and defining for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons,

c) reconstructing an image of the source of photons from said statistical data.

14. A method for using, in a planar or tomographic mode, a device for reconstructing an image of a source of photons from interactions of photons, emitted by this source, the device including a microcomputer or an electronic circuit, the method comprising:

using a detector of a gamma-camera positioned behind a collimator;

using the microcomputer or an electronic circuit to associate with each interaction of photon, emitted by a source of photons, with the detector, a piece of information relating to the depth in the detector of this interaction;

reconstructing an image of the source of photons from said depth information,

wherein the detector is broken down into several pixels, each pixel comprising several superposed voxels, and wherein said microcomputer or said electronic circuit is configured to perform;

determining, for each received photon, the voxel of the detector in which the photon has interacted,

counting, for each voxel of the detector, the number of photons having interacted in this voxel, and defines for each voxel of the detector, a raw or differential statistical datum, a raw datum corresponding to the number of photons counted for the relevant voxel, a differential datum corresponding to a difference between numbers of counted photons, and

reconstructing images from said statistical data.