Apparatus and methods for coronary sinus access

• US 8,016,748 B2
• Filed: 11/08/2005
• Issued: 09/13/2011
• Est. Priority Date: 05/30/2002
• Status: Expired due to Fees

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Leeflang, Stephen Arie, Mourlas, Nicholas J., Miller, David John, Nayak, Asha Shrinivas, Eversull, Christian Scott
• Primary Examiner(s): Sweet; Thomas J
• Assistant Examiner(s): HENDERSON, RYAN N
• Application Number:
  US11/269,976
• Publication Number:
  US 20060084839A1
• Time in Patent Office: 2,135 Days
• Field of Search: 600/104, 600114-117, 600/121, 600/160, 600374-375, 604/96.01, 604/101, 604/4, 604/500, 606/15, 128/898
• US Class Current: 600/115
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/00096 Optical elements
• CPC Class Codes: A61B 1/005 Flexible endoscopes
• CPC Class Codes: A61B 1/018 for receiving instruments
• CPC Class Codes: A61B 1/05 characterised by the image sensor, e.g. camera, being in the distal end portion
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00907 for light
• CPC Class Codes: A61M 25/0147 with movable mechanical means, e.g. pull wires

Abstract

Apparatus and methods for locating morphological features within a body cavity using a catheter including proximal and distal ends, a transparent balloon carried on the distal end, and an optical imaging assembly carried on the distal end for imaging through the balloon. The balloon includes a channel extending therethrough to a lumen extending through the catheter. A guidewire or other localization member is received in the lumen that is extendable through the channel. During use, the catheter is inserted into a right atrium of a heart, and the balloon is expanded and placed against the wall of the heart to locate the coronary sinus. Sufficient force is applied to clear blood between the surface and the wall and clear the field of view of the imaging assembly. The catheter is manipulated to locate the coronary sinus, whereupon the localization member is advanced into the coronary sinus.

Claims

1. A method for accessing a body lumen, comprising:

inserting a distal end of a tubular member into a first body lumen, the tubular member comprising a substantially transparent expandable member thereon in a contracted condition;

expanding the expandable member within the first body lumen;

placing a distal surface of the expanded expandable member in contact with a wall of the first body lumen in order to image the wall through a substantially circular central region the distal surface adjacent and surrounding a central axis of the tubular member;

manipulating the tubular member to move the expandable member along the wall, while imaging the wall through the central region of the distal surface, until a second body lumen is identified; and

after identifying the second body lumen, advancing an instrument from the tubular member into the second body lumen.

2. The method of claim 1, wherein the first body lumen comprises a right atrium of a patient'"'"'s heart, and wherein the second body lumen comprises a coronary sinus ostium.

3. The method of claim 1, wherein the instrument is advanced into the second body lumen to stabilize the distal end of the tubula member.

4. The method of claim 1, wherein the instrument comprises at least one of a lead, a guide wire, a cannula, and a catheter.

5. The method of claim 1, herein the instrument is advanced into the second body lumen through a channel extending through the expandable member that communicates with the second body lumen,

6. The method of claim 5, wherein the channel is disposed concentrically with a central axis of the tubular member, and wherein the tubular member is manipulated to align the channel with the second body lumen.

7. The method of claim 5, wherein the channel is parallel with a central axis of the tubular member, and wherein the tubular member is manipulated to align the channel with the second body lumen.

8. The method of claim 1, wherein the surface of the expanded expandable member is placed in contact with the wall of the first body lumen with sufficient. force to at least partially clear fluid from between the surface and the wall to enhance imaging the wall.

9. The method of claim 1, further comprising delivering a fluid between the surface and the wall to at least partially clear bodily fluid from between the surface and the wall to enhance imaging the wall.

10. The method of claim 1, further comprising expanding an occlusion member on the tubular member to substantially seal the second body lumen from the first body lumen.

11. The method of claim 10, further comprising infusing fluid into the second body lumen.

12. The method of claim 11, wherein the fluid comprises contrast, the method further comprising obtaining a venogram of a location distal to the occlusion member.

13. The method of claim 11, wherein the fluid comprises a therapeutic agent.

14. The method of claim 10, further comprising aspirating fluid from the second body lumen.

15. The method of claim 1, wherein the instrument comprises an electrical device.

16. A method for imaging a wall of a body cavity of a patient, comprising:

inserting a distal end of a tubular member into the body cavity, the tubular member comprising a substantially transparent expandable member thereon in a contracted condition;

expanding the expandable member within the body cavity;

placing a distal surface of the expanded expandable member in contact with a wall of the body cavity in order to image the wail through a substantially circular central region of the distal surface intersecting and surrounded by a central longitudinal axis of the tubular member;

applying sufficient force to at least partially clear fluid from between the central region of the distal surface and the wall to enhance imaging the wall;

manipulating the tubular member to move the expandable member along the wall, while imaging the wall through the central region of the distal surface, until a desired body structure is identified; and

wherein the desired body structure comprises a body lumen communicating with the body cavity, the method further comprising advancing an instrument from the tubular member into the body lumen.

17. The method of claim 16, wherein the tubular member is manipulated by steering the distal end of the tubular member from a proximal end of the tubular member.

18. The method of claim 16, wherein the instrument comprises at least one of a lead, a guide wire, a cannula, and a catheter.

19. The method of claim 16, wherein the tubular member is manipulated to position the body lumen in a field of view through the central region of the distal surface of the expandable member, thereby substantially aligning a channel through the expandable member with the body lumen.

20. The method of claim 19, wherein the instrument is advanced through the channel into the body lumen after the channel is substantially aligned with the body lumen.

21. The method of claim 16, wherein the body cavity comprises a right atrium of a patient'"'"'s heart, and wherein the body lumen comprises a coronary sinus ostium.

22. The method of claim 16, further comprising delivering a fluid between the surface and the wall to at least partially clear bodily fluid from between the surface and the wall to enhance imaging the wall.

23. The method of claim 16, further comprising substantially stabilizing the distal end of the tubular member relative to the wall of the body cavity by advancing at least a portion of the tubular member to extend the distal end beyond. the surface of the expanded expandable member.

24. A method for imaging a wall of a body cavity of a patient, comprising:

inserting a distal end of a tubular member into the body cavity, the tubular member comprising a substantially transparent expandable member thereon in a contracted condition;

expanding the expandable member within the body cavity;

placing a distal surface of the expanded expandable member in contact with a wall of the body cavity in order to image the wall through a substantially circular central region of a distal surface of the expandable member;

manipulating the tubular member to move the expandable member along the wall, while imaging the wall through the central region of the expandable member, until a body lumen is identified;

substantially stabilizing the distal end of the tubular member relative to the wall of the body cavity by advancing at least a portion of the tubular member to extend the distal end beyond the surface of the expanded expandable member; and

advancing an instrument from the tubular member into the body lumen.

25. The method of claim 24, wherein the distal end of the tubular member is stabilized by applying a distal force to the tubular member to press the expandable member against the watt to stabilize the distal end of the tubular member.

26. The method of claim 25, wherein pressing the expandable member results in deformation of the expandable member, thereby substantially stabilizing the distal end of tubular member.

27. The method of claim 25, further comprising imaging one or more tissue structures through the expandable member while the distal end of the tubular member is stabilized.

28. The method of claim 25, wherein a portion of the expandable member is directed into a body lumen communicating with the body cavity when the distal force is applied to stabilize the distal end of the tubular member.

29. The method of claim 24, wherein the distal end of the tubular member is stabilized by advancing the distal end into the body lumen.

30. The method of claim 24, wherein the body cavity comprises a right atrium of a patient'"'"'s heart, and wherein the body lumen comprises a coronary sinus ostium.

31. The method of claim 24, wherein the tubular member comprises a central longitudinal axis extending between proximal and distal ends thereof, and a tubular extension attached eccentrically to the distal end and extending distally from the distal end substantially parallel to the longitudinal axis, the expandable member comprising a proximal end attached to the distal end of the tubular member and a distal end attached to the tubular extension thereon.

32. The method of claim 31, wherein the wall is imaged through the distal surface using an optical imaging element on the distal end that is disposed away from the central longitudinal axis to minimize obstruction of a field of view of the optical imaging element by the tubular extension.

33. A method for accessing a body lumen, comprising:

inserting a distal end of a tubular member into a first body lumen, the tubular member comprising a substantially transparent expandable member thereon in a contracted condition;

expanding the expandable member within the first body lumen.;

placing a distal surface of the expanded expandable member in contact with a wall of the first body lumen in order to image the wall through a substantially circular central region of the distal surface;

manipulating the tubular member to move the expandable member along the wall, while imaging the wall through the central region of the distal surface, until a second body lumen is identified; and

after identifying the second body lumen, advancing the distal end of the tubular member into the second body lumen with the expandable member at least partially expanded.

34. The method of claim 33, wherein the size of the expandable member is adjusted to accommodate the second body lumen.

35. The method of claim 33, wherein the expandable member is partially deflated before advancing the distal end of the tubular member into the second body lumen.

36. A method for imaging a wall of a body cavity of a patient using a tubular member comprising proximal and distal ends defining a central longitudinal axis therebetween, a tubular extension attached eccentrically to the distal end and extending distally from the distal end substantially parallel to the longitudinal axis, and a substantially transparent expandable member comprising a proximal end attached to the distal end of the tubular member and a distal end attached to the tubular extension thereon such that the expandable member defines a distal surface having a central region contacting and surrounding a distal tip of the tubular extension, the method comprising:

inserting the distal end of the tubular member into the body cavity with the expandable member in a contracted condition;

expanding the expandable member within the body cavity;

placing a distal surface of the expanded expandable member in contact with a wall of the body cavity in order to image the wall through the central region of the distal surface using an optical imaging element on the distal end that is disposed away from the central longitudinal axis to minimize obstruction of a field of view of the optical imaging element by the tubular extension;

applying sufficient force to at least partially clear fluid from between the distal surface and the wall to enhance imaging the wall;

manipulating the tubular member to move the expandable member along the wall, while imaging the wall through the central region of the distal surface, until a desired body structure is identified, wherein the desired body structure comprises a body lumen communicating with the body cavity, and

advancing an instrument from the tubular member into the body lumen.

37. The method of claim 36, wherein the tubular member is manipulated by steering the distal end of the tubular member from a proximal end of the tubular member.

38. The method of claim 36, wherein the instrument comprises at least one of a lead, a guide wire, a cannula, and a catheter.

39. The method of claim 36, wherein the tubular member is manipulated to position the body lumen in a field of view through the expandable member, thereby substantially aligning a channel through the expandable member with the body lumen.

40. The method of claim 36, further comprising delivering a fluid between the surface and the wall to at least partially clear bodily fluid from between the surface and the wall to enhance imaging the wall.