Systems and methods for evaluating ventricular dyssynchrony using atrial and ventricular pressure measurements obtained by an implantable medical device
First Claim
1. A method for use with an implantable medical device for determining ventricular contraction intervals, the method comprising:
- detecting a left atrial pressure (LAP) signal;
identifying a c-wave in the detected LAP signal;
detecting a right ventricular pressure (RVP) signal;
identifying an upstroke point in the RVP signal;
determining an interventricular mechanical delay based in part on a time interval between the upstroke point in the RVP signal and the c-wave in the LAP signal; and
controlling therapy delivered by the implantable medical device based on the interventricular mechanical delay.
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Accused Products
Abstract
Techniques are provided for exploiting left atrial pressure (LAP) measurements to determine various ventricular mechanical and electromechanical contraction intervals and for evaluating ventricular dyssynchrony based on those intervals. In one example, LAP measurements are combined with right ventricular pressure (RVP) measurements to determine the interventricular mechanical delay, which is the primary parameter representative of ventricular dyssynchrony. Other intervals determined based, in part, on LAP measurements include the electromechanical delay for the left ventricle (LV), as well as the LV systolic and diastolic intervals. Techniques are also described herein for detecting various RV intervals including the electromechanical delay for the RV, as well as the RV systolic and diastolic intervals.
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Citations
12 Claims
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1. A method for use with an implantable medical device for determining ventricular contraction intervals, the method comprising:
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detecting a left atrial pressure (LAP) signal; identifying a c-wave in the detected LAP signal; detecting a right ventricular pressure (RVP) signal; identifying an upstroke point in the RVP signal; determining an interventricular mechanical delay based in part on a time interval between the upstroke point in the RVP signal and the c-wave in the LAP signal; and controlling therapy delivered by the implantable medical device based on the interventricular mechanical delay. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for use with an implantable medical device for determining an interventricular mechanical delay, the method comprising:
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detecting a right ventricular pressure (RVP) signal and identifying an upstroke point therein; detecting a left atrial pressure (LAP) signal and identifying a c-wave therein; detecting the interventricular mechanical delay based on a time interval between the c-wave of LAP and the upstroke of the RVP; and modifying therapy delivered by the implantable medical device based on the interventricular mechanical delay.
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Specification