Liquid drug delivery devices for use with syringes with widened distal tips

• US 8,016,809 B2
• Filed: 09/24/2008
• Issued: 09/13/2011
• Est. Priority Date: 09/25/2007
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Ben Shalom, Niv, Zinger, Freddy
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): SHUMATE, VICTORIA PEARL
• Application Number:
  US12/679,676
• Publication Number:
  US 20100198148A1
• Time in Patent Office: 1,084 Days
• Field of Search: 604/126, 604/190, 604/403, 604/405, 604/406, 604411-415, 604/537, 604/539, D24/129, D24/130, 215/247, 215/249
• US Class Current: 604/414
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/162 Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube in jet-action syringes A61M5/30; connectors for tubes having sealed ends and a needle for piercing them A61M39/14

Abstract

Liquid drug delivery device includes a housing with a syringe port for sealingly receiving a syringe having a syringe tip ending at a widened distal tip, a vial adapter port with a vial adapter for snap fit receiving a vial, and a drug administration port for administering a liquid drug. The vial adapter is intended to be rotationally detached after a mixing procedure for discarding together with a spent vial. The syringe port additionally includes a single use locking mechanism for securing the syringe to preclude inadvertent syringe detachment under normal use including agitation for reconstitution purposes. The drug administration port has a distal tip preferably similar to a syringe'"'"'s widened distal tip for the same purpose of preventing conventional needles with a female Luer connector being slidingly mounted thereon.

Claims

1. A liquid drug delivery device for use with a syringe having a syringe tip ending at a widened distal tip having an outer diameter D1 and a length L1, and a medicinal vial with a rubber stopper, the device comprising:

(a) a housing having a longitudinal axis, a syringe port and a drug administration port co-directional with said longitudinal axis for correspondingly receiving the syringe and administrating the liquid drug, and a tubular vial adapter port intermediate said syringe port and said drug administration port;

(b) a flow control member rotatably supported in said vial adapter port about an axis of rotation generally perpendicular to said longitudinal axis, said flow control member including an L-shaped mixing flow channel with a radial section for flow communication with said syringe port in a mixing flow control position and an axial section, said flow control member including a peripheral semi-circular administration flow channel for enabling flow communication between said syringe port and said drug administration port in a subsequent administration flow control position,

(c) a vial adapter for telescopically receiving a vial and including an upright tubular male connector and a downward depending tubular cannula for extending into the vial and in flow communication with said male connector,

said vial adapter being initially coupled to said housing for sealing insertion of said male connector in said axial section and being rotationally detachable from said housing whereupon rotation of said vial adapter relative to said housing simultaneously rotates said flow control member from said mixing flow control position to said administration flow control position,

characterized in

said syringe port including an inlet port having an elastomeric tubular sealing member for sealed fluid communication with the syringe and a single use locking mechanism having at least two opposite stopping members for deployment behind the syringe'"'"'s distal tip on insertion of the syringe into said syringe port thereby precluding inadvertent syringe detachment from said syringe port, and

said drug administration port having a widened distal tip for preventing a conventional needle being slidingly mounted thereon.

2. The device according to claim 1 wherein said sealing member is constituted by elastomer tubing having an internal diameter D3 and a free length L3 beyond its attachment point with said inlet port where D3<

D1 and L3>

L1 for sealingly receiving the widened distal tip on forced sliding insertion of the syringe into said syringe port.

3. The device according to claim 1 wherein said sealing member is constituted by an annular elastomer gasket against which the widened distal tip is sealingly urged on sliding insertion of the syringe into said syringe port.

4. The device according to claim 1 wherein said locking mechanism includes a tubular guide member co-axial with said longitudinal axis for assisting in user alignment of the syringe therealong for facilitating insertion of the syringe into said syringe port,

said tubular guide member having with at least two opposite stopping members inwardly converging towards said vial adapter port and terminating at stopping member tips stopping short of said sealing member and defining an aperture with a diameter smaller than the diameter D1 such that the syringe'"'"'s widened distal tip resiliently radially outwardly urges said at least two stopping members which snap therebehind to encircle its syringe tip on forced insertion there through.

5. The device according to claim 4 wherein said locking mechanism includes a solid tubular guide member having at least two resiliently flexible stopping members.

6. The device according to claim 4 wherein said locking mechanism includes a split ring tubular guide member resiliently flexibly connected to said inlet port.

7. The device according to claim 1 wherein said locking mechanism includes a first locking member for snap fitting onto a second locking member on application of a manual compression force directed towards said longitudinal axis for encircling the syringe tip.