Mesh implant with an interlocking knitted structure

• US 8,016,841 B2
• Filed: 06/11/2007
• Issued: 09/13/2011
• Est. Priority Date: 06/11/2007
• Status: Active Grant

• Current Assignee: Novus Scientific AB (Novus Scientific Pte., Ltd.)
• Original Assignee: Novus Scientific Pte., Ltd.
• Inventors: Mathisen, Torbjörn, Magnusson, Henrik
• Primary Examiner(s): Erezo; Darwin
• Assistant Examiner(s): ORKIN, ALEXANDER J
• Application Number:
  US11/808,563
• Publication Number:
  US 20080306494A1
• Time in Patent Office: 1,555 Days
• Field of Search: 623/23.72, 623/23.75, 606/151, 606/154, 606/213, 606/200, 606/228
• US Class Current: 606/151
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2250/003 differing in adsorbability or resorbability, i.e. in adsorption or resorption time
• CPC Class Codes: D04B 21/12 characterised by thread material

Abstract

A resorbable polymeric mesh implant is provided for use in the reconstruction of soft tissue defects. The mesh implant is provided with an interlocking knitted structure comprising two or more sets of fibers with different times of degradation, allowing a stepwise increase in the relative distension of the overall mesh over time. The filamentous fibers are knitted together, wherein the filaments of the first set of fibers are interlaced into the filaments of the second set of fibers and at least partly traverse the knit pattern of the second set of fibers such that the filaments of the first set of fibers lock the movement of the part of the mesh formed by the second set of fibers.

Claims

1. A resorbable polymeric mesh implant for use in reconstruction of soft tissue defects, comprising:

a first arrangement of resorbable material comprising fibers; and

a second arrangement of resorbable material comprising fibers, the second arrangement of resorbable material being substantially degradable at a later point in time than the first arrangement of resorbable material,

wherein the first arrangement of resorbable material is in contact with the second arrangement of resorbable material such that the first arrangement of resorbable material locks movement of the second arrangement of resorbable material by traversing apertures of the second arrangement of resorbable material to maintain relative distension of the mesh implant substantially constant following a time of implantation and until the first arrangement of resorbable material is substantially degraded, such that the mesh implant has a first substantially constant relative distension before the first arrangement is substantially degraded, and

wherein after the first arrangement of resorbable material is substantially degraded, the relative distension of the mesh implant substantially increases,

wherein the first arrangement of resorbable material and the second arrangement of resorbable material have different patterns,

wherein the second arrangement is a fabric having a structural integrity without a presence of the first arrangement, such that the mesh implant has a second relative distension after the first arrangement has substantially degraded, wherein the second relative distension is higher than the first relative distension.

14. The method to repair a soft tissue defect, wherein a resorbable polymeric mesh implant according to claim 1 is used.

15. The resorbable polymeric mesh implant according to claim 1, wherein the polymeric mesh implant is a hernia mesh implant.

16. The resorbable polymeric mesh implant according to claim 1, wherein the arrangements are made of different materials with different resorption times relative to the time of implantation.

17. The resorbable polymeric mesh implant according to claim 1, wherein the mesh implant is fully resorbable.

2. A resorbable polymeric mesh implant for use in reconstruction of soft tissue defects, wherein the mesh implant comprises:

a first set of resorbable polymeric fibers, and

a second set of resorbable polymeric fibers,

wherein the fibers are knitted together,

wherein filaments of said first set of fibers are interlaced into filaments of the second set of fibers and at least partly traverse a knit pattern of the second set of fibers such that the filaments of the first set of fibers lock the movement of the part of the mesh implant formed by the second set of fibers, and

wherein the relative distension of the mesh implant is substantially constant following the time of implantation and until said first set of fibers is substantially degraded, such that the mesh implant has a first substantially constant relative distension before the first set of fibers is substantially degraded, and

wherein the second set of fibers are substantially degraded at a later point in time than the first set of fibers,

wherein the first set of resorbable polymeric fibers and the second set of resorbable polymeric fibers have different patterns,

wherein the second set of resorbable polymeric fibers is a fabric having a structural integrity without a presence of the first set of resorbable polymeric fibers, such that the mesh implant has a second relative distension after the first set of fibers has substantially degraded, wherein the second relative distension is higher than the first relative distension.

3. The resorbable polymeric mesh implant according to claim 2, wherein the mesh implant comprises a third set of fibers that is substantially degraded at a later point in time than the second set of fibers and the relative distension of the mesh implant is substantially changed after the second set of fibers is substantially degraded.

4. The resorbable polymeric mesh implant according to claim 2, wherein the different sets of fibers are made of different materials with different resorption times relative to the time of implantation.

5. The resorbable polymeric mesh implant according to claim 2, wherein the first set of fibers is substantially degraded at a point in time within the time range of 2-40 days following implantation.

6. The resorbable polymeric mesh implant according to claim 2, wherein the last substantially degraded set of fibers is substantially degraded at a point in time within the time range of 3-18 months following implantation.

7. The resorbable polymeric mesh implant according to claim 2, wherein the relative distension of the mesh implant following the time of implantation and until said first set of fibers is substantially degraded is within the range of 0-10%.

8. The resorbable polymeric mesh implant according to claim 2, wherein the relative distension of the mesh implant following the time of substantial degradation of the first set of fibers is above 10%.

9. The resorbable polymeric mesh implant according to claim 2, wherein the polymeric mesh implant is a hernia mesh implant.

10. The resorbable polymeric mesh implant according to claim 2, wherein the mesh implant stretches more in one direction along the plane of the mesh implant than in another direction along the plane of the mesh implant.

11. The resorbable polymeric mesh implant according to claim 2, wherein the polymeric mesh implant is formed into a three-dimensional shape to support an internal body structure.

12. The resorbable polymeric mesh implant according to claim 2, wherein the first set of fibers and/or further sets of fibers has or is incorporated into a knitted structure with an aperture size in the range of 0.1-4.0 mm.

13. The resorbable polymeric mesh implant according to claim 2, wherein the mesh implant is knitted using a technique that produces a mesh that is resistant to runs.

18. The resorbable polymeric mesh implant according to claim 2, wherein the mesh implant is fully resorbable.