Enhanced signal processing for cochlear implants

• US 8,019,431 B2
• Filed: 06/02/2009
• Issued: 09/13/2011
• Est. Priority Date: 06/02/2008
• Status: Active Grant

• Current Assignee: University of Washington
• Original Assignee: University of Washington
• Inventors: Li, Xing, Nie, Kaibao, Atlas, Les, Clark, Charles Pascal, Rubinstein, Jay
• Primary Examiner(s): Manuel; George
• Assistant Examiner(s): WIELAND, ROBERT N
• Application Number:
  US12/476,979
• Publication Number:
  US 20090312820A1
• Time in Patent Office: 833 Days
• Field of Search: 607/57, 600/25
• US Class Current: 607/57
• CPC Class Codes: A61N 1/36038 Cochlear stimulation

Abstract

The restoration of melody perception is a key remaining challenge in cochlear implants. A novel sound coding strategy is proposed that converts an input audio signal into time-varying electrically stimulating pulse trains. A sound is first split into several frequency sub-bands with a fixed filter bank or a dynamic filter bank tracking harmonics in sounds. Each sub-band signal is coherently downward shifted to a low-frequency base band. These resulting coherent envelope signals have Hermitian symmetric frequency spectrums and are thus real-valued. A peak detector or high-rate sampler of half-wave rectified coherent envelope signals in each sub-band further converts the coherent envelopes into rate-varying, interleaved pulse trains. Acoustic simulations of cochlear implants using this new technique with normal hearing listeners, showed significant improvement in melody recognition over the most common conventional stimulation approach used in cochlear implants.

Claims

1. A method for processing an audio input to generate a signal for controlling a cochlear implant for a hearing impaired patient, the method comprising the steps of:

(a) providing an auditory input signal;

(b) performing a coherent demodulation of the auditory input signal to generate a frequency shifted signal, using a targeted temporal pitch trajectory comprising a frequency range of about 50 Hz to about 300 Hz;

(c) processing the frequency shifted signal to generate a relatively low frequency, slowly varying signal that is compatible with the cochlear implant; and

(d) mapping the relatively low frequency, slowly varying signal to at least one of a plurality of cochlear implant stimulation electrodes.

2. The method of claim 1, wherein before the step of performing coherent demodulation of the auditory input signal, further comprising the step of separating the auditory input signal into a plurality of sub bands using a plurality of bandpass filters.

3. The method of claim 2, wherein the step of performing the coherent demodulation of the auditory input signal comprises the steps of:

(a) for each sub band, assuming a carrier portion of the auditory input signal is fixed at a lower boundary of the sub band; and

(b) extracting a coherent envelope for each sub band, each coherent envelope comprising a spectrally shifted real value signal, the frequency shifted signal corresponding to a sum of spectrally shifted real value signals for the plurality of sub bands.

4. The method of claim 1, wherein before the step of performing coherent demodulation of the auditory input signal, further comprising the steps of:

(a) determining a pitch of the auditory input signal over time; and

(b) separating the auditory input signal into a plurality of different harmonics over time as a function of the pitch of the auditory input signal over time.

5. The method of claim 4, wherein the step of performing coherent demodulation of the auditory input signal to generate a frequency shifted signal comprises the step of extracting a coherent envelope for each different harmonic, each coherent envelope comprising a spectrally shifted real value signal, the frequency shifted signal corresponding to a sum of spectrally shifted real value signals for the plurality of harmonics.

6. The method of claim 4, wherein the step of performing coherent demodulation of the auditory input signal to generate a frequency shifted signal comprises the steps of:

(a) performing a Hilbert transform on each harmonic, thereby generating a one-sided analytic signal for each harmonic;

(b) multiplying each one-sided analytic signal by a complex exponential signal, a phase term of the complex exponential signal being a function of a fundamental frequency of the auditory input signal and the targeted temporal pitch trajectory, thereby generating a frequency shifted complex signal for each harmonic; and

(c) isolating a real part of the frequency shifted complex signal for each harmonic, the frequency shifted signal corresponding to a sum of each real part of the frequency shifted complex signal for each harmonic.

7. The method of claim 4, wherein the step of performing coherent demodulation of the auditory input signal to generate a frequency shifted signal comprises the steps of:

(a) multiplying each harmonic by a cosine function having a phase term that is a function of a fundamental frequency of the auditory input signal and a targeted temporal pitch trajectory, thereby generating a frequency shifted harmonic signal for each harmonic; and

(b) applying a low pass filter to each frequency shifted harmonic signal to remove double-frequency components, the frequency shifted signal corresponding to a sum of filtered frequency shifted harmonic signals.

8. The method of claim 7, wherein the targeted temporal pitch trajectory comprises a frequency range of about 50 Hz to about 300 Hz.

9. The method of claim 1, wherein the step of processing the frequency shifted signal to generate a relatively low frequency, slowly varying signal compatible with the cochlear implant comprises the steps of:

(a) passing the frequency shifted signal through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted signal; and

(b) modulating the non-negative envelope signal with a biphasic pulse train at a constant rate to generate the relatively low frequency, slowly varying signal that is compatible with the cochlear implant.

10. The method of claim 1, wherein the step of processing the frequency shifted signal to generate a relatively low frequency, slowly varying signal compatible with the cochlear implant comprises the steps of:

(a) passing the frequency shifted signal through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted signal;

(b) performing peak detection on the non-negative envelope signal to obtain a peak envelope signal; and

(c) processing the peak envelope signal to generate the relatively low frequency, slowly varying signal compatible with the cochlear implant.

11. A method for controlling a cochlear implant for a hearing impaired patient, the method comprising the steps of:

(a) providing an auditory input signal;

(b) determining a pitch of the auditory input signal over time;

(c) separating the auditory input signal into a plurality of harmonics over time as a function of the pitch over time;

(d) for each of the plurality of harmonics, shifting the frequency of the harmonic downward, generating a plurality of frequency shifted harmonics;

(e) for each frequency shifted harmonic, performing an amplitude modulation, generating a plurality of frequency shifted and amplitude modulated harmonics; and

(f) mapping each frequency shifted and amplitude modulated harmonic to different ones of a plurality of cochlear implant stimulation electrodes.

12. The method of claim 11, wherein the step of shifting the frequency of the harmonic downward for each harmonic comprises the step of performing a coherent demodulation of each harmonic to obtain the plurality of frequency shifted harmonics.

13. The method of claim 12, wherein the step of performing the coherent demodulation of each harmonic to obtain the plurality of frequency shifted harmonics comprises the steps of:

(a) performing a Hilbert transform on each harmonic, thereby generating a one-sided analytic signal for each harmonic;

(b) multiplying each one-sided analytic signal by a complex exponential signal, a phase term of the complex exponential signal being a function of a fundamental frequency of the auditory input signal and a targeted temporal pitch trajectory, thereby generating a frequency shifted complex signal for each harmonic; and

(c) isolating a real part of the frequency shifted complex signal for each harmonic, the frequency shifted signal corresponding to a sum of real parts of the frequency shifted complex signal for each harmonic.

14. The method of claim 13, wherein the targeted temporal pitch trajectory comprises a frequency range of about 50 to about 300 Hz.

15. The method of claim 12, wherein the step of performing the coherent demodulation of each harmonic to obtain the plurality of frequency shifted harmonics comprises the steps of:

(a) multiplying each harmonic by a cosine function whose phase term is a function of a fundamental frequency of the auditory input signal and a targeted temporal pitch trajectory, thereby generating a frequency shifted harmonic signal for each harmonic; and

(b) applying a low pass filter to each frequency shifted harmonic signal to remove double-frequency components, the frequency shifted signal corresponding to a sum of the frequency shifted harmonic signals.

16. The method of claim 11, wherein the step of performing an amplitude modulation for each frequency shifted harmonic comprises the steps of:

(a) passing each frequency shifted harmonic through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted harmonic; and

(b) modulating each non-negative envelope signal with a biphasic pulse train at a constant rate to generate the plurality of frequency shifted and amplitude modulated harmonics.

17. The method of claim 11, wherein the step of performing an amplitude modulation for each frequency shifted harmonic comprises the steps of:

(a) passing the frequency shifted signal through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted signal;

(b) performing peak detection on each non-negative envelope signal to obtain a plurality of peak envelope signals; and

(c) processing each peak envelope signal to generate the plurality of frequency shifted and amplitude modulated harmonics.

18. A cochlear implant for a hearing impaired patient, comprising:

(a) at least one acoustic sensor for providing an auditory input signal;

(b) a power supply;

(c) a plurality of stimulation electrodes; and

(d) a processor for controlling the plurality of stimulation electrodes based on the auditory input signal, the processor implementing the functions of;

(i) performing a coherent demodulation of the auditory input signal to generate a frequency shifted signal, using a targeted temporal pitch trajectory comprising a frequency range of about 50 Hz to about 300 Hz;

(ii) processing the frequency shifted signal to generate a relatively low frequency, slowly varying signal that is compatible with the cochlear implant; and

(iii) mapping the relatively low frequency, slowly varying signal to at least one of the plurality of stimulation electrodes.

19. The cochlear implant of claim 18, wherein the processor further implements the functions of:

(a) determining a pitch of the auditory input signal over time; and

(b) separating the auditory input signal into a plurality of different harmonics over time as a function of the pitch over time.

20. The cochlear implant of claim 19, wherein the processor generates the frequency shifted signal by implementing the functions of:

(a) performing a Hilbert transform on each harmonic, thereby generating a one-sided analytic signal for each harmonic;

(b) multiplying each one-sided analytic signal by a complex exponential signal, a phase term of the complex exponential signal being a function of a fundamental frequency of the auditory input signal and the targeted temporal pitch trajectory, thereby generating a frequency shifted complex signal for each harmonic; and

(c) isolating a real part of the frequency shifted complex signal for each harmonic, the frequency shifted signal corresponding to a sum of real parts of the frequency shifted complex signal for each harmonic.

21. The cochlear implant of claim 19, wherein the processor generates the frequency shifted signal by implementing the functions of:

(a) multiplying each harmonic by a cosine function having a phase term that is a function of a fundamental frequency of the auditory input signal and a targeted temporal pitch trajectory;

thereby generating a frequency shifted harmonic signal for each harmonic; and

(b) applying a low pass filter to each frequency shifted harmonic signal to remove double-frequency components, the frequency shifted signal corresponding to a sum of frequency shifted harmonic signals.

22. The cochlear implant of claim 18, wherein the processor manipulates the frequency shifted signal to generate the relatively low frequency, slowly varying signal that is compatible with the cochlear implant frequency shifted signal by implementing the functions of:

(a) passing the frequency shifted signal through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted signal; and

(b) modulating the non-negative envelope signal with a biphasic pulse train at a constant rate to generate the relatively low frequency, slowly varying signal compatible with the cochlear implant.

23. The cochlear implant of claim 18, wherein the processor manipulates the frequency shifted signal to generate the relatively low frequency, slowly varying signal compatible with the cochlear implant frequency shifted signal by implementing the functions of:

(a) passing the frequency shifted signal through a half-wave rectifier to obtain a non-negative envelope signal that carries both amplitude and periodicity information of the frequency shifted signal;

(b) performing peak detection on the non-negative envelope signal to obtain a peak envelope signal; and

(c) processing the peak envelope signal to generate the relatively low frequency, slowly varying signal that is compatible with the cochlear implant.

24. A cochlear implant for a hearing impaired patient, comprising:

(a) at least one acoustic sensor for providing an auditory input signal;

(b) a power supply;

(c) a plurality of stimulation electrodes; and

(d) a processor for controlling the plurality of stimulation electrodes based on the auditory input signal, the processor implementing the functions of;

(i) determining a pitch of the auditory input signal over time;

(ii) separating the auditory input signal into a plurality of harmonics over time as a function of the pitch over time;

(iii) for each of the plurality of harmonics, shifting the frequency of the harmonic downward, generating a plurality of frequency shifted harmonics;

(iv) for each frequency shifted harmonic, performing an amplitude modulation, generating a plurality of frequency shifted and amplitude modulated harmonics; and

(v) mapping each frequency shifted and amplitude modulated harmonic to at least one of a plurality of stimulation electrodes.