Continual flow pin washer

• US 8,020,571 B2
• Filed: 10/16/2008
• Issued: 09/20/2011
• Est. Priority Date: 10/17/2007
• Status: Active Grant

• Current Assignee: Aushon BiosyStems, Inc. (Quanterix Corporation)
• Original Assignee: Aushon BiosyStems, Inc. (Quanterix Corporation)
• Inventors: Honkanen, Peter, Bradbury, Dave, Bukys, Albert
• Primary Examiner(s): Perrin; Joseph L.
• Assistant Examiner(s): Osterhout; Benjamin
• Application Number:
  US12/252,487
• Publication Number:
  US 20090101175A1
• Time in Patent Office: 1,069 Days
• Field of Search: 134/22.18, 134/25.4, 134/34, 134/54, 134/102.2, 134/118, 134/140, 134/154, 134/166.R, 134/187, 134/171, 422/501, 422/510, 422/527, 422/551, 436/43, 436/49, 436/54
• US Class Current: 134/171
• CPC Class Codes: B01L 13/02 for receptacle or instruments
• CPC Class Codes: B01L 3/0244 using pins
• CPC Class Codes: B08B 3/04 Cleaning involving contact with liquid
• CPC Class Codes: B41J 29/17 Cleaning arrangements
• CPC Class Codes: G01N 2035/1037 Using surface tension, e.g. pins or wires
• CPC Class Codes: G01N 35/1004 Cleaning sample transfer devices

Abstract

A multi-chambered deposition pin wash station is provided. The wash station includes a lower chamber and an upper drain basin connected by a plurality of wash tubes. Cleaning fluid is provided to the lower chamber and passes through the cleaning tubes into the upper drain basin. The cleaning tubes are adapted to clean a single deposition pin with a single tube per wash cycle.

Claims

1. A pin wash station, comprising:

a lower chamber;

a drain basin;

a plurality of cleaning tubes, each cleaning tube having an inlet end and an outlet end, each tube inlet end being in fluid communication with the lower chamber, the terminus of all tube inlet ends being below a substantially horizontal reference plane, each tube outlet end being in fluid communication with the drain basin such that fluid that exits the outlet end of the tube passes into the drain basin, and each tube outlet end adapted to receive at least a portion of a deposition pin; and

a vent tube, the vent tube having an inlet end and an outlet end, the inlet end being disposed in and in fluid communication with the lower chamber, the terminus of the vent tube inlet end being above the level of the cleaning tube inlet ends relative to the substantially horizontal reference plane, and the outlet end being in direct fluid communication with the drain basin.

2. The pin wash station of claim 1, wherein the vent tube outlet end includes a portion directed away from the cleaning tube outlet ends.

3. The pin wash station of claim 1, wherein the vent tube includes a surface tension reduction feature disposed within the vent tube for reducing surface tension of fluid within the vent tube.

4. The pin wash station of claim 3, wherein the surface tension reduction feature includes a wire disposed within the vent tube.

5. The pin wash station of claim 1, wherein the substantially horizontal reference plane corresponds to a level of a cleaning fluid in the lower chamber.

6. The pin wash station of claim 1, wherein at least one of the plurality of cleaning tube outlet ends has a fluid surface tension reduction feature.

7. The pin wash station of claim 6, wherein the surface tension reduction feature is a notch in a lip of at least one of the tube outlet ends.

8. The pin wash station of claim 6, wherein the surface tension reduction feature includes a surface finish on an outside surface of at least one of the tube outlet ends.

9. The pin wash station of claim 8, wherein the surface finish includes at least one of a bead blasting treatment, a grit blasting treatment, a hydrophilic treatment, and a hydrophobic treatment.

10. The pin wash station of claim 1, wherein at least one of the plurality of cleaning tubes has a flow restriction feature positioned to correspond to a predetermined location on at least a portion of the deposition pin.

11. The pin wash station of claim 10, wherein the predetermined location is the terminus of the deposition pin.

12. The pin wash station of claim 10, wherein the flow restriction feature is a swage in at least a portion of the cleaning tube.

13. The pin wash station of claim 10, wherein the flow restriction feature includes a narrowing insert within at least a portion of the cleaning tube.

14. The pin wash station of claim 10, wherein an inner surface of the flow restriction feature includes a surface treatment that generates at least one of rotation and turbulence in a cleaning fluid flowing through the flow restriction feature.

15. A system, comprising:

a plurality of pins adapted to deposit an array of material dots on a receiving surface; and

a pin wash station, including;

a lower chamber;

a drain basin;

a plurality of cleaning tubes, each cleaning tube having an inlet end and an outlet end, each tube inlet end being in fluid communication with the lower chamber, the terminus of all tube inlet ends being below a substantially horizontal reference plane, each tube outlet end being in fluid communication with the drain basin, and each tube outlet end adapted to receive one of the plurality of pins; and

a vent tube, the vent tube having an inlet end and an outlet end, the inlet end being disposed in and in fluid communication with the lower chamber, the terminus of the vent tube inlet end being above the level of the cleaning tube inlet ends relative to the substantially horizontal reference plane, and the outlet end being in direct fluid communication with the drain basin.

16. The system of claim 15, wherein the substantially horizontal reference plane corresponds to a level of a cleaning fluid in the lower chamber.

17. The system of claim 15, wherein the plurality of pins includes at least one deposition pin printing array including at least 192 deposition pins.

18. The system of claim 15, wherein at least one of the plurality of cleaning tubes includes at least one of a fluid surface tension reduction feature, a fluid surface tension reducing surface treatment, and a flow restriction feature.

19. The system of claim 15, wherein the number of cleaning tubes is equal to the number of pins and the arrangement of the cleaning tubes corresponds to the arrangement of the pins.

20. The system of claim 15, wherein the number of cleaning tubes is less than the number of pins.

21. The system of claim 20, wherein the plurality of pins are arranged in rows having a first spacing between the rows, the cleaning tubes are arranged in rows having a second spacing between the rows, and the second spacing is an integer multiple of the first spacing.