Method and system for treatment of neurocardiogenic syncope
First Claim
Patent Images
1. A method for operating a cardiac rhythm management device, comprising:
- sensing ventricular depolarizations and generating ventricular sense signals in accordance therewith;
deriving a ventricular rate as a function of a plurality of time intervals between successive ventricular senses;
detecting a ventricular bradycardia when the derived ventricular rate is below a specified bradycardia limit value;
initiating delivery of one or more electrostimulation pulses to the ventricle while the ventricle is refractory when ventricular bradycardia is detected from the derived ventricular rate to thereby increase the contractility of the ventricle, wherein such electrostimulation pulses are timed to occur within a refractory interval following a ventricular sense or pace;
pacing the ventricle upon expiration of an escape interval without receipt of a ventricular sense, the inverse of the escape interval being the lower rate limit; and
,increasing the lower rate limit when bradycardia is detected.
3 Assignments
0 Petitions
Accused Products
Abstract
A method and apparatus for treating or preventing neurocardiogenic syncope is disclosed. Upon detection of bradycardia or a drop in blood pressure indicating the onset of syncope, electrostimulation pulses are delivered during the heart'"'"'s refractory period. The pulses are non-excitatory but increase myocardial contractility and thereby increase cardiac output.
79 Citations
18 Claims
-
1. A method for operating a cardiac rhythm management device, comprising:
-
sensing ventricular depolarizations and generating ventricular sense signals in accordance therewith; deriving a ventricular rate as a function of a plurality of time intervals between successive ventricular senses; detecting a ventricular bradycardia when the derived ventricular rate is below a specified bradycardia limit value; initiating delivery of one or more electrostimulation pulses to the ventricle while the ventricle is refractory when ventricular bradycardia is detected from the derived ventricular rate to thereby increase the contractility of the ventricle, wherein such electrostimulation pulses are timed to occur within a refractory interval following a ventricular sense or pace; pacing the ventricle upon expiration of an escape interval without receipt of a ventricular sense, the inverse of the escape interval being the lower rate limit; and
,increasing the lower rate limit when bradycardia is detected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A cardiac rhythm management device, comprising:
-
a sensing amplifier for sensing ventricular depolarizations through a sensing channel and generating ventricular sense signals in accordance therewith; a pulse generator for delivering electrostimulation pulses to a ventricle through a stimulation channel; a controller for controlling the delivery of stimulation pulses to the ventricle; wherein the controller is programmed to derive a ventricular rate as a function of a plurality of time intervals between successive ventricular senses, detect a ventricular bradycardia when the derived ventricular rate is below a specified bradycardia limit value, and initiate delivery of one or more stimulation pulses while the ventricle is refractory when ventricular bradycardia is detected from the derived ventricular rate to thereby increase the contractility of the ventricle, wherein such electrostimulation pulses are timed to occur within a refractory interval following a ventricular sense or pace; and
,wherein the controller is configured to pace the ventricle upon expiration of an escape interval without receipt of a ventricular sense, the inverse of the escape interval being the lower rate limit, and to increase the lower rate limit when bradycardia is detected. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
-
Specification