Modular vascular prosthesis and methods of use

• US 8,025,694 B2
• Filed: 12/21/2007
• Issued: 09/27/2011
• Est. Priority Date: 02/25/2005
• Status: Expired due to Fees

• Current Assignee: Abbott Laboratories Limited (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Laboratories Limited (Abbott Laboratories Incorporated)
• Inventors: DeMore, Duane, Strauss, David P., Bialas, Michael R., Barbier, Robert, Bregulla, Rainer
• Primary Examiner(s): Severson; Ryan J
• Application Number:
  US11/962,463
• Publication Number:
  US 20090005848A1
• Time in Patent Office: 1,376 Days
• Field of Search: 623 115- 118, 623/1.38
• US Class Current: 623/1.16
• CPC Class Codes: A61F 2/852 Two or more distinct overlapping stents
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/30019 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2002/30428 made by inserting a protrusion into a slot
• CPC Class Codes: A61F 2002/30604 modular
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91566 connected trough to trough
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

The present invention relates a vascular prosthesis and related assembly methods that includes a plurality of modular segments inter-engaged by flexible, and preferably lockable, inter-engageable elements forming joints or other connector areas. The segments may have a number of different mechanical properties and may be assembled by the clinician, through mechanical or chemical joining, to customize the prosthesis for a specific patient or application.

Claims

1. A method of assembling a modular prosthesis comprising:

providing a plurality of interlocking modular segments, wherein each interlocking modular segment has a proximal and a distal end, a plurality of struts and a plurality of bends disposed between the proximal and distal ends, a ring shaped male interface element at the proximal end of the module, and a rounded female interface element at the distal end of the module; and

joining the plurality of interlocking modular segments by inserting the ring shaped male interface element at the proximal end of one interlocking modular segment into the rounded female interface element at the distal end of another interlocking modular segment, the plurality of interlocking module segments being joined together in a delivery configuration and a deployed configuration.

2. The method of claim 1, wherein the one and the another interlocking modular segments fixedly engage one another, thereby causing the interlocking modular segments not to move axially relative to one another.

3. The method of claim 2, wherein the one and the another interlocking modular segments fixedly engage each other by mechanically interlocking, by bonding or by welding the one and the another interlocking modular segments to one another.

4. The method of claim 1, wherein each ring shaped male interface element and/or each rounded female interface element comprises an extension of a corresponding one of the plurality of struts.

5. The method of claim 1, further comprising providing at least two interlocking modular segments having different lengths.

6. The method of claim 1, further comprising providing at least two interlocking modular segments made of different materials.

7. The method of claim 6, wherein one of the different materials is biodegradable.

8. The method of claim 6, wherein the different materials possess different mechanical properties.

9. The modular vascular prosthesis of claim 1, wherein the one and the another interlocking modular segments have different strut configurations.

10. The method of claim 1, wherein the one interlocking modular segment is balloon expandable and the another interlocking modular segment is self-expanding.

11. The method of claim 1, wherein at least one of the one or another interlocking modular segments comprises a drug-eluting polymeric material.

12. The method of claim 1, wherein at least one of the one or another interlocking modular segments includes a side-branch aperture.

13. The method of claim 1, wherein at least one of the one or another interlocking modular segments includes a cover comprising a biocompatible graft material.

14. The method of claim 1, further comprising:

another plurality of interlocking modular segments extending from the distal end of the one interlocking modular segment, individual ones of the plurality of interlocking modular segments interleaved with individual ones of the one interlocking modular segment; and

an additional plurality of interlocking modular segments extending from the proximal end of the another interlocking modular segment, individual ones of the plurality of interlocking modular segments interleaved with individual ones of the another interlocking modular segment.

15. A modular vascular prosthesis having a delivery configuration and a deployed configuration, the modular vascular prosthesis comprising:

a plurality of interlocking modular segments each having a proximal end and a distal end, and a plurality of struts and bends therebetween,

wherein each of the plurality of interlocking modular segments further has a ring shaped male interface element at the proximal end and a rounded, open-ended female interface element at the distal end, each rounded, open-ended female interface element being disposed at the end of a single strut of the plurality of struts, the cooperating ring shaped male interface element of one interlocking modular segment and rounded, open-ended female interface element of another interlocking modular segment interlocking both in a delivery configuration and a deployed configuration.

16. The modular vascular prosthesis of claim 15, further comprising:

a first interlocking modular end segment having a proximal and a distal ends, a plurality of struts and a plurality of bends at the proximal end, and a rounded female interface element at the distal end;

a second interlocking modular end segment having a proximal and distal ends, a plurality of struts and a plurality of bends at the distal end, and a ring shaped male interface element at the proximal end;

wherein the plurality of interlocking modular segments are joined to each other by inserting the ring shaped male interface element at the proximal end of a first interlocking modular segment of the plurality of interlocking modular segments into the rounded female interface element at the distal end of a second interlocking modular segment of the plurality of interlocking modular segment;

wherein at least one of the plurality of interlocking modular segments is joined to the first interlocking modular end segment by inserting the ring shaped male interface element at the proximal end of the interlocking modular segment to the rounded female interface element at the distal end of the first interlocking modular end segment; and

wherein at least one of the plurality of interlocking modular segments is joined to the second interlocking modular end segment by inserting the ring shaped male interface element at the proximal end of the interlocking modular end segment to the rounded female interface element at the distal end of the interlocking modular segment.

17. The modular vascular prosthesis of claim 16, wherein at least two interlocking modular segments of the plurality of interlocking module segments have different lengths.

18. The modular vascular prosthesis of claim 16, wherein at least two interlocking modular segments of the plurality of interlocking module segments are made of different materials.

19. The system of claim 18, wherein one of the different materials is biodegradable.

20. The system of claim 18, wherein the different materials possess different mechanical properties.

21. The system of claim 18, wherein the plurality of struts and bends has an angled branch configuration.

22. A vascular prosthesis having a delivery configuration and a deployed configuration, the vascular prosthesis comprising:

a first modular segment and a second modular segment, each of the first modular segment and the second modular segment having a proximal end and a distal end, and a plurality of struts and bends therebetween,

wherein each of the first modular segment and the second modular segment has at least one ring shaped male interface element formed on at least one selected strut of the plurality of struts, and at least one rounded, open-ended female interface formed on at least one selected strut of the plurality of struts, each ring shaped male interface and each rounded, open-ended female interface being disposed at the end of a single strut of the plurality of struts, the cooperating ring shaped male interface element of the first modular segment and the rounded, open-ended female interface element of the second modular segment interlocking both in a delivery configuration and a deployed configuration.

23. The vascular prosthesis of claim 22, wherein the plurality of struts are disposed in an angled branch configuration.

24. The vascular prosthesis of claim 22, wherein the first and the second modular segments have different lengths.

25. The vascular prosthesis of claim 22, wherein the first and the second modular segments are made of different materials.

26. The vascular prosthesis of claim 22, wherein the first and the second modular segments possess different mechanical properties.