Electroporation ablation apparatus, system, and method
First Claim
Patent Images
1. An ablation device, comprising:
- an elongate member comprising first and second channels;
first and second substantially straight probes disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis; and
first and second electrodes coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes;
wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes;
wherein the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough.
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Abstract
A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate member comprising first and second channels. First and second probes are disposed within the respective first and second channels, where the first and second probes each define a central axis. First and second electrodes are coupled to distal ends of the respective first and second probes. A distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the central axis of the at least one of the first and second probes.
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Citations
35 Claims
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1. An ablation device, comprising:
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an elongate member comprising first and second channels; first and second substantially straight probes disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis; and first and second electrodes coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes; wherein the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough. - View Dependent Claims (2, 3, 4, 5)
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6. An ablation system, comprising:
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an elongate member comprising first and second channels; first and second substantially straight probes disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis; first and second electrodes coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes; and an electrical waveform generator electrically coupled to the first and second electrodes to generate an irreversible electroporation electrical (IRE) waveform sufficient to ablate tissue located proximate to the first and second electrodes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes; wherein the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14)
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15. A method, comprising:
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locating an elongate member comprising first and second channels within a body cavity proximate to a tissue treatment region, wherein a first and a second substantially straight probe are disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis, and wherein a first and a second electrode are coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes; adjusting a distance between the first and second electrodes by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes; and receiving a tissue sample through a sharp distal end and an aperture in communication with a bore formed within either one of the first and second probes. - View Dependent Claims (16, 17, 18, 19, 20, 21)
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22. An ablation device, comprising:
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an elongate member comprising first and second channels; first and second substantially straight probes disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis; and first and second electrodes coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes; wherein the second probe comprises a sharp distal end and an aperture in communication with a bore formed within the second probe to receive a tissue sample therethrough. - View Dependent Claims (23, 24, 25, 26)
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27. An ablation system, comprising:
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an elongate member comprising first and second channels; first and second substantially straight probes disposed within the respective first and second channels, the first and second substantially straight probes each defining a central axis; first and second electrodes coupled to and juxtaposed with distal ends of the respective first and second substantially straight probes; and an electrical waveform generator electrically coupled to the first and second electrodes to generate an irreversible electroporation electrical (IRE) waveform sufficient to ablate tissue located proximate to the first and second electrodes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second substantially straight probes about the respective central axis of the at least one of the first and second substantially straight probes; wherein the second probe comprises a sharp distal end and an aperture in communication with a bore formed within the second probe to receive a tissue sample therethrough. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35)
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Specification