Systems for filling a sample array by droplet dragging
First Claim
1. An array filling system for filling a platen, the system comprising:
- a platen having a platen surface and an array of receptacles to be filled, the receptacles having an internal surface and the receptacles separated by the platen surface;
a liquid transfer device capable of holding liquid; and
a controller configured;
(a) to position the liquid transfer device in the proximity to the platen surface;
(b) to cause a droplet of liquid to (i) be dispensed from the liquid transfer device and (ii) contact the platen surface, wherein surface tension maintains contact between the droplet and the liquid transfer device; and
(c) to move the liquid transfer device across the platen surface and over the receptacles to be filled thereby causing sequential communication of liquid in the droplet with the interior surface of each receptacle.
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Abstract
Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface, the system comprising: a liquid transfer device capable of holding liquid; and a controller configured to position the liquid transfer device in proximity to the platen surface and to move the liquid transfer device across the surface and over the receptacles to be filled so as to cause sequential communication of liquid in the liquid transfer device with the interior surface of each receptacle.
307 Citations
19 Claims
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1. An array filling system for filling a platen, the system comprising:
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a platen having a platen surface and an array of receptacles to be filled, the receptacles having an internal surface and the receptacles separated by the platen surface; a liquid transfer device capable of holding liquid; and a controller configured; (a) to position the liquid transfer device in the proximity to the platen surface; (b) to cause a droplet of liquid to (i) be dispensed from the liquid transfer device and (ii) contact the platen surface, wherein surface tension maintains contact between the droplet and the liquid transfer device; and (c) to move the liquid transfer device across the platen surface and over the receptacles to be filled thereby causing sequential communication of liquid in the droplet with the interior surface of each receptacle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An array filling system for transferring liquid to an array of receptacles, the system comprising:
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a platen including a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface; a liquid transfer device capable of holding liquid; and a controller configured to position the liquid transfer device in proximity to the platen surface and to move the liquid transfer device across the surface and over the receptacles to be filled so as to cause sequential communication of liquid in the liquid transfer device with the interior surface of each receptacle. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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Specification