Method for the diagnosis and prognosis of malignant diseases
First Claim
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1. A method of treating cancer in a subject comprising administering to said subject a therapeutically effective amount of an anti-nucleolin antibody and a pharmaceutically acceptable carrier, wherein said nucleolin antibody is substantially non-immunogenic to human.
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Abstract
Methods for the treatment of tumors and cancer by exploiting the surface expression of the usually nuclear-localized protein, nucleolin.
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7 Claims
- 1. A method of treating cancer in a subject comprising administering to said subject a therapeutically effective amount of an anti-nucleolin antibody and a pharmaceutically acceptable carrier, wherein said nucleolin antibody is substantially non-immunogenic to human.
- 5. A method of treating cancer in a subject comprising administering to said subject a therapeutically effective amount of an antinucleolin antibody, a chemotoxic or chemotherapeutic agent and a pharmaceutically acceptable carrier.
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7. A method of treating cancer in a subject comprising administering to said subject a therapeutically effective amount of an antinucleolin antibody and a pharmaceutically acceptable carrier, and further treating said subject with radiation therapy.
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