19,26,27-trinor-1α,25-dihydroxyvitamin D3 compounds
First Claim
1. A method of treating a subject suffering from a biological disorder, comprising administering an effective amount of a compound or a composition comprising an effective amount of the compound and a pharmaceutical carrier to the subject, wherein the biological disorder is selected from renal osteodystrophy, secondary hyperparathyroidism, psoriasis, type I diabetes, lupus, rheumatoid arthritis, hypercalcemia, asthma or eczema, or a cancer selected from leukemia, colon cancer, breast cancer, or prostate cancer, and the compound has the formula 1,
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Accused Products
Abstract
Compounds of formula 1 are provided where X1, X2, and X3 are independently selected from H or hydroxy protecting groups, and R1 and R2 have the definitions provided herein. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
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Citations
15 Claims
- 1. A method of treating a subject suffering from a biological disorder, comprising administering an effective amount of a compound or a composition comprising an effective amount of the compound and a pharmaceutical carrier to the subject, wherein the biological disorder is selected from renal osteodystrophy, secondary hyperparathyroidism, psoriasis, type I diabetes, lupus, rheumatoid arthritis, hypercalcemia, asthma or eczema, or a cancer selected from leukemia, colon cancer, breast cancer, or prostate cancer, and the compound has the formula 1,
Specification