Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
First Claim
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1. A cardiac rhythm management system, comprising:
- an atrio-ventricular delay (AVD) calculator adapted to receive one or more measured atrio-ventricular time intervals (AVs) each being a time interval between an atrial event and an intrinsic ventricular event and calculate one or more optimal AVDs using the one or more measured AVs and a predetermined equation relating each AV of the one or more measured AVs to each optimal AVD of the one or more optimal AVDs, the each optimal AVD providing for a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, when ventricular pacing pulses are delivered using the each optimal AVD.
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Abstract
A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchrony or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system providing an option for near optimal pacing of multiple hemodynamic parameters. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal.
152 Citations
20 Claims
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1. A cardiac rhythm management system, comprising:
an atrio-ventricular delay (AVD) calculator adapted to receive one or more measured atrio-ventricular time intervals (AVs) each being a time interval between an atrial event and an intrinsic ventricular event and calculate one or more optimal AVDs using the one or more measured AVs and a predetermined equation relating each AV of the one or more measured AVs to each optimal AVD of the one or more optimal AVDs, the each optimal AVD providing for a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, when ventricular pacing pulses are delivered using the each optimal AVD. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for operating a cardiac rhythm management system, the method comprising:
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measuring one or more atrio-ventricular time intervals (AVs) each between an atrial event and an intrinsic ventricular event; calculating one or more optimal atrio-ventricular delays (AVDs) using the one or more AVs and a predetermined equation relating each AV of the one or more AVs to each optimal AVD of the one or more optimal AVDs, the each optimal AVD providing for a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, when ventricular pacing pulses are delivered using the each optimal AVD; and delivering ventricular pacing pulses using the calculated one or more optimal AVDs. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification