Multi-reservoir implantable pump with patient controlled actuation

• US 8,034,029 B2
• Filed: 05/25/2005
• Issued: 10/11/2011
• Est. Priority Date: 05/25/2005
• Status: Expired due to Fees

• Current Assignee: Aqulinx Medical, Inc.
• Original Assignee: Palyon Medical Corporation
• Inventors: Lederer, Klaus G., Steinbach, Bernd
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Price; Nathan R
• Application Number:
  US11/136,771
• Publication Number:
  US 20060271021A1
• Time in Patent Office: 2,330 Days
• Field of Search: 604/151, 604/153, 60428801-28804, 604/246, 604/93.01, 604/890.1, 604/891.1, 604/892.1, 604131-133, 604/140, 604/141, 604/145, 604/249
• US Class Current: 604/153
• CPC Class Codes: A61M 5/141 with capillaries for restricting fluid flow
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure
• CPC Class Codes: A61M 5/155 pressurised by gas introduced into the reservoir
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

A multiple reservoir or chambered implantable pump is disclosed. The pump according to the present invention is particularly useful in allowing for multiple constant flow rates to be provided from an otherwise constant flow implantable pump. The pump is also useful in allowing for housing of multiple active substances. A multiple reservoir implantable pump is also disclosed, which has at least one chamber capable of providing a constant flow rate and at least one chamber capable of being utilized for patient controlled injections.

Claims

1. An implantable pump comprising:

a housing and two flexible membranes disposed within said housing, said housing and said two flexible membranes defining at least a first, second and third chamber;

an outlet in fluid communication with said first and second chambers;

a first replenishment opening in fluid communication with said first chamber and a first septum sealing the first replenishment opening; and

a second replenishment opening in fluid communication with said second chamber and a second septum sealing the second replenishment opening; and

a patient controlled actuation mechanism in fluid communication with said second chamber,

wherein said two flexible membranes are attached to each other to entirely surround said third chamber.

2. The implantable pump according to claim 1, wherein said third chamber houses a propellant capable of expanding isobarically.

3. The implantable pump according to claim 2, wherein expansion of said third chamber causes fluid contained within said first and second chambers to be dispelled therefrom.

4. The implantable pump according to claim 1, wherein said patient controlled actuation mechanism includes a valve assembly capable of being actuated by a patient.

5. The implantable pump according to claim 4, wherein selective operation of said valve assembly is accomplished by one or more magnets.

6. The implantable pump according to claim 5, wherein said valve assembly further includes a first cylinder housing a first piston, and a second cylinder housing a second piston.

7. The implantable pump according to claim 6, wherein displacement of said first piston causes actuation of a dose of an active substance to a patient.

8. The implantable pump according to claim 7, further comprising means for selectively actuating said one or more magnets.

9. The implantable pump according to claim 8, further comprising means for preventing a patient from over utilizing said patient controlled actuation mechanism.

10. An implantable pump comprising:

a housing having first and second portions;

a first flexible membrane captured between said first and second portions;

a second flexible membrane captured between said first and second portions;

a first chamber defined by said first portion of said housing and said first flexible membrane;

a second chamber defined by said second portion of said housing and said second flexible membrane;

a third chamber defined by said first and second flexible membranes;

a first replenishment opening in fluid communication with said first chamber and a first septum sealing the first replenishment opening; and

a second replenishment opening in fluid communication with said second chamber and a second septum sealing the second replenishment opening;

an outlet in fluid communication with said first and second chambers; and

a patient controlled actuation mechanism in fluid communication with one of said first and second chambers.

11. The implantable pump according to claim 10, wherein said first and second chambers house active substances and said third chamber houses a propellant capable of expanding isobarically.

12. The implantable pump according to claim 11, wherein expansion of said third chamber causes the active substances contained within said first and second chambers to be dispelled therefrom.

13. The implantable pump according to claim 12, wherein said first chamber includes a first active substance and said second chamber includes a second active substance.

14. The implantable pump according to claim 10, wherein said patient controlled actuation mechanism includes a valve assembly capable of being actuated by the patient.

15. The implantable pump according to claim 14, wherein selective operation of said valve assembly is accomplished by one or more magnets.

16. The implantable pump according to claim 15, wherein said valve assembly further includes a first cylinder housing a first piston, and a second cylinder housing a second piston.

17. The implantable pump according to claim 16, wherein displacement of said first piston causes actuation of a dose of an active substance to a patient.

18. The implantable pump according to claim 17, further comprising means for selectively actuating said one or magnets.

19. The implantable pump according to claim 18, further comprising means for preventing a patient from over utilizing said patient controlled actuation mechanism.

20. An implantable pump comprising:

a housing having first and second portions;

a first flexible membrane;

a second flexible membrane;

a first chamber defined by said housing and said first flexible membrane, said first chamber housing a first active substance;

a second chamber defined by said housing and said second flexible membrane, said second chamber housing a second active substance;

a third chamber housing a propellant capable of expanding isobarically;

a first replenishment opening in fluid communication with said first chamber ands first septum sealing the first replenishment opening; and

a second replenishment opening in fluid communication with said second chamber and a second septum sealing the second replenishment opening;

a catheter in fluid communication with said first and second chambers; and

a patient controlled actuation mechanism in fluid communication with said second chamber and said catheter, said patient controlled actuation mechanism including;

a valve assembly capable of being actuated by a patient through the use of one or more magnets, said valve assembly further including a first cylinder housing a first piston and a second cylinder housing a second piston, wherein displacement of said first piston causes actuation of a dose of said second active substance to the patient,

wherein said first and second flexible membranes are captured between said first and second portions to completely surround said third chamber.