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Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells

  • US 8,034,329 B2
  • Filed: 10/03/2008
  • Issued: 10/11/2011
  • Est. Priority Date: 10/05/2007
  • Status: Expired due to Fees
First Claim
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1. A method of treating a patient having a disease of or damage to at least one kidney, comprising administering to the patient a homogeneous population of cells obtained from human umbilical cord tissue in an amount effective to treat the disease or damage, wherein the umbilical cord tissue is substantially free of blood, and wherein the population of cells is capable of self-renewal and expansion in culture and has the potential to differentiate;

  • does not produce CD31, CD34, CD117 or HLA-DR; and

    expresses, relative to a human fibroblast, mesenchymal stem cell, or iliac crest bone marrow cell, increased levels of interleukin 8 and reticulon 1.

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