Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
First Claim
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1. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-6-Hydroxy-8-{1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylamino]ethyl}-4H-benzo[1,4]oxazin-3-one hydrochloride.
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Abstract
Enantiomerically pure compounds of general formula 1
wherein the groups R1, R2, R3, R4, and X− may have the meanings given in the claims and in the specification, processes for preparing them and the use thereof as pharmaceutical compositions, particularly as pharmaceutical compositions for the treatment of respiratory complaints.
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Citations
40 Claims
- 1. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-6-Hydroxy-8-{1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylamino]ethyl}-4H-benzo[1,4]oxazin-3-one hydrochloride.
- 9. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-8-{2-[2-(2,4-Difluorophenyl)-1,1-dimethylethylamino]-1-hydroxyethyl}-6-hydroxy-4H-benzo[1,4]oxazin-3-one hydrochloride.
- 17. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-8-{2-[2-(3,5-Difluorophenyl)-1,1-dimethylethylamino]-1-hydroxyethyl}-6-hydroxy-4H-benzo[1,4]oxazin-3-one hydrochloride.
- 25. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-8-{2-[2-(4-Ethoxyphenyl)-1,1-dimethylethylamino]-1-hydroxyethyl}-6-hydroxy-4H-benzo[1,4]oxazin-3-one hydrochloride.
- 33. A method for the treatment of respiratory complaints comprising administering to a patient a therapeutically effective amount of R-8-{2-[2-(4-Fluorophenyl)-1,1-dimethylethylamino]-1-hydroxyethyl}-6-hydroxy-4H-benzo[1,4]oxazin-3-one hydrochloride.
Specification