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Methods for noninvasively measuring analyte levels in a subject

  • US 8,036,727 B2
  • Filed: 06/02/2006
  • Issued: 10/11/2011
  • Est. Priority Date: 08/11/2004
  • Status: Active Grant
First Claim
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1. A method of non-invasively estimating hemoglobin within biological tissue using optical coherence tomography (OCT) comprising:

  • providing light having scattering properties sensitive to hemoglobin levels, the light comprising multiple wavelengths;

    splitting the light into a sample beam and a reference beam;

    irradiating biological tissue with the sample beamobtaining measurements of reflected light from the sample beam irradiating the biological tissue;

    identifying portions of the measurements of the reflected light corresponding to measurements taken within a blood vessel within the biological tissue; and

    estimating a hemoglobin level based on the measurements taken within the blood vessel.

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