Injection device and method

• US 8,038,648 B2
• Filed: 06/02/2006
• Issued: 10/18/2011
• Est. Priority Date: 06/03/2005
• Status: Expired due to Fees

• Current Assignee: Innovacell Biotechnologie GmbH
• Original Assignee: Innovacell Biotechnologie GmbH
• Inventors: Marksteiner, Rainer
• Primary Examiner(s): Stigell; Theodore J
• Assistant Examiner(s): Thomas, Jr.; Bradley G
• Application Number:
  US11/916,184
• Publication Number:
  US 20090234319A1
• Time in Patent Office: 1,964 Days
• Field of Search: 604/117, 604/506, 604/272, 604/521, 604/239, 604/116, 604/500, 604/181, 604/507, 604/19, 604/48, 600/459, 600/461, 600/463, 600/437
• US Class Current: 604/117
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

An injection device (100) for injecting a substance into an organism (1) is described, comprising a guide device (10) with a lumen (11) in which an injection tool (21) is arranged in a displaceable manner, a displacement device (20) to which the injection tool (21) is connected, and a holder device (30) that forms a support for the guide and displacement devices (10, 20), said guide and displacement devices (10, 20) being displaceably arranged on the holder device (30). A method for injecting a substance into an organism (1) is also described.

Claims

1. An injection device for injecting a substance into an organism, comprising:

a guide device with a lumen in which an injection tool is arranged in a displaceable manner, so that the injection tool is movable relative to the entire guide device,

a displacement device to which the injection tool-is connected, and

a holder device that forms a support for the guide and displacement devices, the guide and displacement devices being arranged on the holder device such that they can be displaced relative to one another and relative to the holder device, wherein;

the guide and displacement devices can be adjusted independently of one another on the holder device,

the entire guide device is movable relative to the holder device,

the lumen is angled relative to a center line of the guide device at an outlet end of the guide device, so that a free end of the injection tool leaving the outlet end moves away from the holder device in an injection direction having a radial component, and

a penetration depth of the free end of the injection tool in the injection direction is determined by the adjustment position of the guide device relative to the holder device.

2. The injection device according to claim 1, in which the holder device has a forward stop which limits a forward movement of the displacement device relative to the holder device.

3. The injection device according to claim 1, in which the holder device has a backward stop which limits a backward movement of the guide device relative to the holder device.

4. The injection device according to claim 1, in which the holder device has a tubular structure and the guide device being arranged internally within the holder device and the displacement device being arranged externally on the holder device.

5. The injection device according to claim 1, in which the guide device and the displacement device are arranged such that they can be rotated about a longitudinal axis of the holder device.

6. The injection device according to claim 5, in which a rotary bearing is provided, in which the holder device with the guide device and the displacement device can be rotated about the longitudinal axis of the holder device.

7. The injection device according to claim 6, in which the rotary bearing has a mandrel which blocks a rotation of the holder device in a pushed-forward state of the displacement device.

8. The injection device according to claim 7, in which the displacement device has a perforated ring which cooperates with the mandrel of the rotary bearing.

9. The injection device according to claim 8, in which the perforated ring has guide holes, wherein at least one of a number and an angular distribution of the guide holes is selected as a function of the desired geometric distribution of the injection into the organism.

10. The injection device according to claim 1, in which the holder device has a first clamping device for fixing the guide device relative to the holder device.

11. The injection device according to claim 10, in which the first clamping device comprises a clamping screw with a flushing channel, through which a flushing fluid can be introduced into the guide device.

12. The injection device according to claim 1, in which the guide device has a channel for accommodating an imaging probe.

13. The injection device according to claim 12, in which the holder device has a second clamping device for fixing the probe in the channel.

14. The injection device according to claim 1, in which the displacement device has a mount for holding an injection reservoir.

15. The injection device according to claim 14, in which the mount for holding the injection reservoir has an adjusting screw for metering the substance that is to be injected.

16. The injection device according to claim 1, in which a sensor device is provided, which comprises at least one sensor for detecting the position of at least one of the guide, displacement and holder devices.

17. The injection device according to claim 1, in which the holder device has a return spring, by means of which the displacement device can be returned from a pushed-forward operating position.

18. A method for injecting a substance into an organism, use being made of an injection device according to claim 1, said method comprising the steps:

positioning the guide device on the holder device so that an outlet end has a predefined position relative to an injection site in the organism,

actuating the displacement device so as to push the injection tool forward to the injection site, and

injecting the substance by means of the injection tool.

19. The method according to claim 18, comprising the further step:

positioning an imaging probe in the guide device and recording an image of the injection site.

20. The method according to claim 18, comprising the further step:

positioning an imaging probe outside the injection device .

21. The method according to claim 18, in which the actuation of the displacement device comprises pushing it forward as far as the forward stop.

22. The method according to claim 18, in which the injection takes place using a syringe plunger which is attached to the displacement device.

23. The injection device according to claim 1, in which the displacement device has a pulled-back operating position, wherein the injection tool is pulled back toward the holder device, and a pushed-forward operating position, wherein the injection tool is pushed forward so that its free end leaves the lumen of the guide device, wherein the position of the guide device relative to the displacement device defines a free exit length and a penetration depth of the injection tool in the pushed-forward operating position of the displacement device.