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High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances

  • US 8,043,250 B2
  • Filed: 08/25/2006
  • Issued: 10/25/2011
  • Est. Priority Date: 05/18/2005
  • Status: Active Grant
First Claim
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1. A method of treating, preventing, or ameliorating a medical condition of a mammal, comprising:

  • treating a topical site of a mammal using a device,immediately removing the device from the topical site after the device has perforated the skin, andapplying an effective amount of an agent to the topical site to allow the agent to penetrate into the body of the mammal,wherein the device comprises an array of microstructures, andwherein the microstructure has an aspect ratio of about 10;

    1 or higher.

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