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Flow-inflated diffusion therapeutic delivery

  • US 8,043,258 B2
  • Filed: 01/24/2006
  • Issued: 10/25/2011
  • Est. Priority Date: 01/24/2006
  • Status: Expired due to Fees
First Claim
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1. A device for delivering therapeutic agent to a target site in a vessel having a vessel wall and a vessel interior, the device comprising:

  • a first infusion lumen having a proximal end, a distal end, and a longitudinal axis, the first infusion lumen containing a therapeutic agent;

    a second infusion lumen having a proximal end, a distal end, and a longitudinal axis, the second infusion lumen containing a substance for mixing with the therapeutic agent; and

    an inflatable balloon disposed at the distal ends of the first and second infusion lumens and in fluid communication with the first and second infusion lumens, the balloon having a proximal end, a distal end and an intermediate surface between the proximal end and distal end, the intermediate surface configured to contact the vessel wall, the inflatable balloon being the only balloon in fluid communication with the first and second infusion lumens, the inflatable balloon having an exit outlet in only the distal end of the balloon;

    wherein the device is configured to exert pressure, such that when the exerted pressure is greater than a target pressure the therapeutic agent exits the inflatable balloon through the exit outlet into the vessel interior.

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