Micro-valve

• US 8,048,041 B2
• Filed: 10/25/2007
• Issued: 11/01/2011
• Est. Priority Date: 10/26/2006
• Status: Expired due to Fees

• Current Assignee: Insulet Netherlands B.V. (Insulet Corporation)
• Original Assignee: Cellnovo Limited (Cellnovo Group SA)
• Inventors: Shapley, Julian Llewellyn, Cefai, Joseph John
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): THOMAS, JR, BRADLEY G
• Application Number:
  US12/447,223
• Publication Number:
  US 20100137784A1
• Time in Patent Office: 1,468 Days
• Field of Search: 604/30, 604/131, 604246-247, 6048901-8921, 604236-237, 604248-250, 604/537, 604/34, 604/167.03, 600/561, 137/496, 417/413.1
• US Class Current: 604/246
• CPC Class Codes: A61M 2039/2433 Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
• CPC Class Codes: A61M 2039/246 being fixed along all or a part of its periphery
• CPC Class Codes: A61M 2205/0244 Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: F16K 2099/0086 Medical applications
• CPC Class Codes: F16K 2099/0094 Micropumps
• CPC Class Codes: F16K 99/0001 Microvalves microdevices B81B1/00; manufacture or treatment of devices or systems in or on a substrate B81C1/00; microfluidic structures B01L3/5027; micropumps F04B19/006
• CPC Class Codes: F16K 99/0015 Diaphragm or membrane valves
• CPC Class Codes: Y10T 137/7837 Direct response valves [i.e., check valve type]

Abstract

A one-way valve comprises a seat and a membrane having an inner portion that is stretched over the seat, wherein, in use, the inner membrane portion is selectively deflected from the seat such that a fluid path is created from one side of the membrane to the other so as to open the valve, and wherein an outer peripheral portion of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion. The one-way valve may be used in a pump for an infusion system.

Claims

1. A one-way valve comprising:

a membrane having an inner portion and an outer portion;

a raised seat that extends beyond a plane of the outer membrane portion; and

a conduit extending through the seat to define an inlet of the valve, wherein the inner portion of the membrane is stretched over the raised seat to close the conduit therethrough in a closed condition of the valve, the inner membrane portion being selectively deflected from the raised seat in an open condition of the valve to open said conduit such that a fluid path is created from one side of the membrane to the other, and wherein an outer peripheral portion of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion.

2. A valve according to claim 1, further comprising a rigid frame embedded in the outer portion of the membrane.

3. A valve according to claim 2, wherein the rigid frame is of a material selected from the group of materials including:

metal, glass, ceramic and polymer.

4. A valve according to claim 1, wherein the outer portion of the membrane has a different material composition, or dimension, to that of the inner portion.

5. A valve according to claim 1, wherein the relative stiffness of the inner and outer portions of the membrane is selected according to a desired activation pressure at which the valve opens.

6. A valve according to claim 1, wherein at least one aperture is formed in the membrane that forms a portion of the fluid path across the membrane.

7. A valve according to claim 6, wherein the number and arrangement of the apertures is selected according to a desired activation pressure at which the valve opens.

8. A valve according to claim 6, further comprising a first body portion that includes the valve seat.

9. A valve according to claim 8, wherein a first cavity is defined by a recess in the first body portion that provides a fluid path from the inlet to the at least one aperture in the membrane when the membrane is displaced from the valve seat as the valve opens.

10. A valve according to claim 9, further comprising a second body portion on the opposite side of the membrane to the first body portion.

11. A valve according to claim 10, wherein the second body portion has a fluid conduit formed there through defining an outlet of the valve.

12. A valve according to claim 10, wherein a second cavity is defined by a recess in the second body portion into which the inner membrane portion moves when the valve opens.

13. A valve according to claim 11, wherein the outlet opens into the second cavity.

14. A valve according to claim 13, wherein the second cavity creates a fluid path between the at least one aperture in the membrane and the outlet.

15. A valve according to claim 8, wherein the outer portion of the membrane is fixed to the first body portion.

16. A valve according to claim 10, wherein the outer portion of the membrane is fixed between the first and second body portions.

17. A valve according to claim 15, wherein the fixing of the membrane is by means of clamping, clipping, gluing, bonding or welding.

18. A valve according to claim 16, wherein at least one of the first and second body portions is aligned at one or more designated alignments points with the outer membrane portion.

19. A valve according to claim 18, wherein a peripheral edge of at least one of the 10 first and second body portions is aligned with a peripheral edge of the membrane.

20. A valve according to claim 16, wherein at least one of the first and second body portions has a channel formed therein, and compressible sealing material is disposed within the channel for sealing the valve.

21. A valve according to claim 16, wherein at least one of the first and second body portions contact the outer membrane portion at a substantially incompressible interface.

22. A valve according to claim 1, wherein the membrane is of a material selected from the group of materials including:

rubber, silicone, and an elastomer.

23. A valve according to claim 1, wherein at least an outer portion of 25 the valve seat has a uniform height such that, when the valve is closed, the inner portion of the membrane uniformly seals around the valve seat.

24. A pump for pumping liquid therapeutic product,

comprising:

a valve, the valve including;

a membrane having an inner portion and an outer portion;

a raised seat that extends beyond a plane of the outer membrane portion; and

a conduit extending through the seat to define an inlet of the valve wherein the inner portion of the membrane is stretched over the raised seat to close the conduit therethrough in a closed condition of the valve, the inner membrane portion being selectively deflected from the raised seat such that a fluid path is created from one side of the membrane to the other so as to open the valve, and

wherein an outer peripheral portion of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion; and

a pumping chamber having an inlet and an outlet means for causing a change in a volume of the pumping chamber, wherein at least one of the inlet and outlet includes said valve.

25. A pump according to claim 24, wherein a portion of the pumping chamber volume is bounded by the inner membrane portion of said valve.

26. A pump according to claim 24, wherein a fluid conduit connects the pumping chamber to a fluid inlet of the outlet valve.

27. A pump according to claim 24, wherein the inlet valve has a lower activation pressure than the outlet valve.

28. A pump according to claim 27, wherein the valve seat of the inlet valve extends beyond a plane of the outer membrane portion of the inlet valve towards the inner membrane portion to a lesser extent than does the valve seat of the outlet valve.

29. An infusion system comprising:

a pump, the pump including a pumping chamber having an inlet and an outlet means for causing a change in a volume of the pumping chamber, wherein at least one of the inlet and outlet includes a valve, the valve including;

a membrane having an inner portion and an outer portion;

a raised seat that extends beyond a plane of the outer membrane portion having a conduit formed therethrough defining an inlet of the valve; and

a conduit extending through the seat to define an inlet of the valve, wherein the inner portion of the membrane is stretched over the raised seat to close the conduit in a closed condition of the valve, the inner membrane portion being selectively deflected from the raised seat such that a fluid path is created from one side of the membrane to the other, and

wherein an outer peripheral portion of the membrane is stiffer than the inner portion such that the membrane deflection is substantially restricted to only the inner portion.