Cross-checking of transthoracic impedance and acceleration signals

• US 8,050,764 B2
• Filed: 10/29/2003
• Issued: 11/01/2011
• Est. Priority Date: 10/29/2003
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Freeberg, Scott
• Primary Examiner(s): Patel; Niketa
• Assistant Examiner(s): HOLMES, REX R
• Application Number:
  US10/696,729
• Publication Number:
  US 20050096704A1
• Time in Patent Office: 2,925 Days
• Field of Search: 607 4- 28, 607/42, 600/547, 600500-519, 600/529
• US Class Current: 607/42
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

A first chamber minute ventilation rate is determined based on a first transthoracic impedance signal received from a first chamber of a heart and a second chamber minute ventilation rate is determined based on a second transthoracic impedance signal received from a second chamber of the heart. A processor compares the minute ventilation rates to determine a rate. In one embodiment, an accelerometer sensor provides data for evaluating propriety of a rate. Before implementing a rate change, signals from multiple sensors are cross-checked.

Claims

1. A device configured to be coupled to a heart, the device comprising:

an exciter to generate a current field in the heart;

a first pair of electrodes;

a second pair of electrodes; and

a processor coupled to the first pair of electrodes and the second pair of electrodes and adapted to generate first impedance information as a function of a first voltage received by the first pair of electrodes in response to the current field, generate second impedance information as a function of a second voltage received by the second pair of electrodes in response to the current field, determine a first ventilation rate using the first impedance information, determine a second ventilation rate using the second impedance information, and compare the first ventilation rate to the second ventilation rate to determine whether the first ventilation rate differs from the second ventilation rate.

2. The device of claim 1 wherein the processor is adapted to generate an error code if the first ventilation rate differs from the second ventilation rate.

3. The device of claim 1 wherein the processor is adapted to alternately monitor the first pair of electrodes and the second pair of electrodes.

4. The device of claim 1 further including a therapy circuit coupled to the processor wherein the therapy circuit is adapted to deliver a therapy using a result of comparing the first ventilation rate to the second ventilation rate.

5. The device of claim 4 wherein the therapy circuit includes a pulse generator.

6. The device of claim 1 wherein the processor includes a filter to pass frequencies in a ventilation band.

7. The device of claim 1 further including an accelerometer coupled to the processor and adapted to provide an acceleration signal and wherein the processor is adapted to cross check the first ventilation rate and the second ventilation rate with the acceleration signal.

8. The device of claim 7 wherein the processor is adapted to generate a pacing rate using impedance information selected from one of the first impedance information and the second impedance information using a result of comparing the first ventilation rate to the second ventilation rate and a result of cross checking the first ventilation code and the second ventilation code with the acceleration signal.

9. An implantable system configured to be coupled to a heart in a thorax, the system comprising:

a plurality of sensors, each sensor adapted to sense a thoracic parameter and provide a signal, the plurality of sensors including a first ventilation sensor adapted to sense a first impedance associated with a first chamber of the heart in the thorax and a second ventilation sensor adapted to sense a second impedance associated with a second chamber of the heart;

a therapy circuit adapted to deliver therapy to the heart; and

a processor coupled to each sensor of the plurality of sensors and coupled to the therapy circuit and wherein the processor is adapted to compare the signals received from the plurality of sensors and adjust a pacing rate using a result of the comparison.

10. The system of claim 9 wherein the plurality of sensors includes an acceleration sensor.

11. The system of claim 9 further including an excitation circuit coupled to the heart and adapted to provide a transthoracic current field.

12. An implantable device comprising:

an excitation channel to generate a current field in a heart;

a first impedance sensor to generate a first impedance signal based on a first voltage associated with a first chamber of the heart;

a second impedance sensor to generate a second impedance signal based on a second voltage associated with a second chamber of the heart;

a first accelerometer to generate a first acceleration signal based on a detected acceleration associated with the heart;

a signal processor coupled to the first impedance sensor and adapted to generate a first ventilation signal using the first impedance signal and coupled to the second impedance sensor and adapted to generate a second ventilation signal using the second impedance signal; and

a processor adapted to receive the first ventilation signal, the second ventilation signal and the first acceleration signal and adapted to cross check the first ventilation signal and the second ventilation signal with the first acceleration signal.

13. The implantable device of claim 12 wherein the first accelerometer has a first axis of sensitivity and further including a second accelerometer having a second axis of sensitivity wherein the first axis intersects the second axis and further wherein the processor is adapted to receive the second acceleration signal.

14. The implantable device of claim 12 further including a telemetry circuit coupled to the processor and adapted to communicate with a remote programmer.

15. The implantable device of claim 13 wherein the processor is adapted to cross check the first ventilation signal and the second ventilation signal with the second acceleration signal.

16. A method comprising:

receiving a plurality of input signals corresponding to two or more chambers of a heart, the plurality of input signals including a first ventilation rate derived from a first impedance associated with a first chamber of the heart and a second ventilation rate derived from a second impedance associated with a second chamber of the heart;

using a processor to detect a similarity between signals of the plurality of input signals including at least the first ventilation rate and the second ventilation rate; and

delivering therapy to the heart based on the detected similarity.

17. The method of claim 16 wherein receiving a plurality of input signals includes receiving a first accelerometer signal from a first accelerometer, the first accelerometer disposed proximate the heart.

18. The method of claim 17 wherein receiving a plurality of input signals includes receiving a second accelerometer signal from a second accelerometer, the second accelerometer disposed proximate the heart, the first accelerometer having a first axis of sensitivity and the second accelerometer having a second axis of sensitivity and wherein the first axis intersects the second axis.

19. The method of claim 17 wherein delivering therapy includes delivering a first therapy regimen if the similarity exists in the first ventilation rate and the second ventilation rate and delivering a second therapy regimen if the similarity does not exist in the first ventilation rate and the second ventilation rate.

20. The method of claim 19 wherein receiving the plurality of input signals includes receiving an acceleration signal and wherein delivering a second therapy regimen includes selecting a therapy regimen based on the acceleration signal.

21. The method of claim 16 wherein receiving a plurality of input signals includes generating an excitation current field using a first electrode pair and sensing a voltage using a second electrode pair.

22. The method of claim 16 wherein determining therapy includes selecting the therapy and wherein using the processor to compare each input signal includes identifying an inappropriate input signal in the plurality of input signals and wherein delivering therapy includes de-emphasizing the inappropriate input signal in selecting the therapy.

23. A system configured to be coupled to a thorax including a heart, the system comprising:

means for generating a current field in the thorax;

means for generating a first ventilation signal based on a first transthoracic impedance measured by a first pair of electrodes responsive to a first chamber of the heart in the thorax;

means for generating a second ventilation signal based on a second transthoracic impedance measured by a second pair of electrodes responsive to a second chamber of the heart;

first accelerometer means adapted to be coupled to the heart and adapted to provide a first acceleration signal as a function of a sensed acceleration associated with the heart along a first axis;

processor means coupled to the means for generating the first ventilation signal and coupled to the means for generating the second ventilation signal and coupled to the first accelerometer means and adapted to generate a code as a function of a detected similarity between the first ventilation signal, the second ventilation signal and the first acceleration signal; and

therapy means coupled to the processor means and adapted to deliver therapy to the heart as a function of the detected similarity.

24. The system of claim 23 further including a second accelerometer means coupled to the heart and adapted to provide a second acceleration signal as a function of a sensed acceleration associated with the heart along a second axis, wherein the first axis intersects the second axis.

25. The system of claim 23 further including telemetry means coupled to the processor means and adapted to communicate with a remote programmer.