System and method for an injection using a syringe needle

• US 8,052,645 B2
• Filed: 07/23/2008
• Issued: 11/08/2011
• Est. Priority Date: 07/23/2008
• Status: Active Grant

• Current Assignee: Avant Medical Corporation
• Original Assignee: Avant Medical Corporation
• Inventors: Magers, Corey M., Koerner, Richard J., Slate, John B., Burk, Michael W.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): MATNEY, BROOKE MARIE
• Application Number:
  US12/178,447
• Publication Number:
  US 20100022955A1
• Time in Patent Office: 1,203 Days
• Field of Search: 604/131, 604/187, 604/167, 604/95.01, 604/195, 604/197, 604/198, 604/110, 604/192, 604/154
• US Class Current: 604/154
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/6045 having complementary physical shapes for indexing or registration purposes
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.

Claims

1. A system for injecting a fluid medicament into a patient which comprises:

a removable and disposable cassette having a latch mechanism;

a hypodermic syringe engageable with the latch mechanism for latching the syringe within the disposable cassette;

a reusable injector;

a fixation member for holding the disposable cassette on or in the injector in a fixed position during the operation of the injector;

a first motor mounted on or in the injector, the first motor being engageable with the disposable cassette for selectively latching and unlatching the syringe within the disposable cassette, and engageable with the syringe for moving the unlatched syringe within the disposable cassette between a first position and a second position;

a second motor mounted on or in the injector, the second motor being engageable with the syringe for expelling the fluid medicament from the syringe; and

a computer mounted on or in the injector for coordinated control of the first and second motors,

wherein the disposable cassette contains the hypodermic syringe comprising the injection needle when the disposable cassette is removed from the injector.

2. A system as recited in claim 1 wherein the hypodermic syringe comprises:

a syringe chamber for holding the fluid medicament therein;

an injection needle extending from the syringe chamber; and

a plunger slidably mounted for advancement into the syringe chamber to expel fluid medicament therefrom through the injection needle.

3. A system as recited in claim 2 wherein the first position is characterized by the injection needle being withdrawn and concealed within the disposable cassette, and the second position is characterized by the injection needle extending from the disposable cassette for expelling the fluid medicament from the syringe.

4. A system as recited in claim 3 wherein the latched syringe is fixedly held in the first position within the disposable cassette.

5. A system as recited in claim 4 wherein a duty cycle requires, in sequence:

computer control of the first motor for movement of the unlatched syringe at a predetermined speed from the first position to the second position;

computer control of the second motor for advancement of the plunger into the syringe chamber at a predetermined rate for expelling fluid medicament from the syringe; and

computer control of the first motor for withdrawal of the syringe from the second position to the first position and for activation of the latch to fixedly hold the syringe in the first position within the disposable cassette.

6. A system as recited in claim 5 wherein the predetermined speed for advancement of the syringe from the first position to the second position is approximately 0.1 to 1 m/s.

7. A system as recited in claim 3 wherein the disposable cassette is formed with an orifice to allow for extension of the injection needle from the disposable cassette, and the system further comprises a skin sensor mounted on the injector adjacent the orifice to generate a contact signal whenever the orifice is positioned against the skin of the patient.

8. A system as recited in claim 1 wherein the disposable cassette further comprises:

a cassette body defining the fixation member; and

a sleeve slidingly mounted on or in the cassette body for movement between the first position and the second position,

wherein the syringe is fixedly held in the sleeve for movement therewith, and

wherein the latch mechanism includes a first part formed on the cassette body and a second part formed on the sleeve.

9. A system for injecting a fluid medicament into a patient, the system comprising:

a reusable injector; and

a removable and disposable cassette containing a hypodermic syringe including a syringe chamber for holding the fluid medicament therein and an injection needle extending from the syringe chamber;

the reusable injector including;

a first motor for moving the syringe within the disposable cassette between a first position and a second position while the disposable cassette is held on or in the injector in a fixed position;

a second motor for expelling the fluid medicament from the syringe chamber and through the injection needle; and

a computer for coordinated control of the first and second motors,

wherein the disposable cassette contains the hypodermic syringe including the syringe chamber and the injection needle when the disposable cassette is removed from the injector.

10. A system as recited in claim 9 wherein the hypodermic syringe further includes a plunger in the syringe chamber for expelling the fluid medicament therefrom through the injection needle.

11. A system as recited in claim 10 wherein the computer causes the first motor to move the syringe at a predetermined speed from the first position to the second position, wherein computer causes the second motor to move the plunger in the syringe chamber at a predetermined rate for expelling fluid medicament from the syringe chamber and through the injection needle;

and wherein the computer causes the first motor to move the syringe from the second position to the first position.

12. A system as recited in claim 11 wherein the predetermined speed is approximately 0.1 to 1 m/s.

13. A system as recited in claim 9 wherein the injection needle is concealed within the disposable cassette in the first position, and wherein the injection needle extends out from within the disposable cassette in the second position.

14. A system as recited in claim 9 wherein the disposable cassette includes an orifice through which the injection needle extends out from within the disposable cassette if the syringe is in the second position.

15. A system as recited in claim 9 wherein the injector further includes a skin sensor for establishing that the disposable cassette is positioned against the skin of the patient.

16. A system as recited in claim 9 wherein the disposable cassette includes:

a housing; and

a sleeve slidingly disposed in the housing for movement between the first position and the second position,

wherein the syringe is fixedly held in the sleeve for movement therewith.

17. A system as recited in claim 16 wherein disposable cassette further includes a latch mechanism, the latch mechanism including a protrusion formed on the cassette and a detent formed on the sleeve.

18. A method for injecting a fluid medicament from a syringe into a patient comprising:

providing a removable and disposable cassette containing a hypodermic syringe, the syringe including a syringe chamber for holding the fluid medicament therein and an injection needle extending from the syringe chamber;

mounting the cassette containing the hypodermic syringe on or in a reusable injector;

holding the cassette on or in the injector in a fixed position while moving the syringe within the cassette between a first position and a second position with a first motor of the injector to extend the injection needle out from within the cassette, into the patient;

expelling the fluid medicament from the syringe chamber, through the injection needle and into the patient, with a second motor of the injector;

removing the cassette containing the hypodermic syringe including the syringe chamber and the injection needle, from the injector; and

controlling the operation of the first and second motors with a computer.

19. A method as recited in claim 18 wherein the syringe moves from the first position to the second position at a predetermined speed of approximately 0.1 to 1 m/s.

20. A method as recited in claim 18 further comprising moving the syringe within the cassette from the second position to the first position with the first motor of the injector to withdraw the injection needle from the patient and conceal the injection needle within the cassette.