Peptide nanostructures and methods of generating and using the same
First Claim
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1. A method of generating a discrete tubular, discrete spherical or discrete planar nanostructure, the method comprising incubating a plurality of peptide molecules under conditions which favor formation of the discrete tubular, discrete spherical or discrete planar nanostructure, wherein each of said peptide molecules comprises no more than 4 amino acids and comprises Phe-Phe having substituted or unsubstituted phenyl.
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Abstract
A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
130 Citations
19 Claims
- 1. A method of generating a discrete tubular, discrete spherical or discrete planar nanostructure, the method comprising incubating a plurality of peptide molecules under conditions which favor formation of the discrete tubular, discrete spherical or discrete planar nanostructure, wherein each of said peptide molecules comprises no more than 4 amino acids and comprises Phe-Phe having substituted or unsubstituted phenyl.
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9. A memory cell, comprising:
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(a) an electrode; and (b) a discrete tubular, discrete spherical or discrete planar nanostructure composed of a plurality of peptides each including no more than 4 amino acids and comprising Phe-Phe haying substituted or unsubstituted phenyl, said nanostructure being capable of assuming one of at least two states; said nanostructure and said electrode being designed and constructed such that when electrical current flows through said electrode, said nanostructure transforms from a first state of said at least to states to a second state of said at least to states.
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10. A mechanical transmission device, comprising a first discrete tubular, discrete spherical or discrete planar nanostructure and a second discrete tubular, discrete spherical or discrete planar nanostructure, said first and said second nanostructure being operatively associated thereamongst such that a motion of said first nanostructure generates a motion of said second nanostructure, wherein at least one of said first and said second nanostructures is composed of a plurality of peptides each includes no more than 4 amino acids and comprising Phe-Phe having substituted or unsubstituted phenyl.
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11. A heat transfer device, comprising a nanofluid and a channel for holding said nanofluid, said nanofluid comprising discrete tubular, discrete spherical or discrete planar nanostructures suspended in a fluid, wherein at least a portion of said nanostructures is composed of a plurality of peptides, each including no more than 4 amino acids and comprising Phe-Phe having substituted or unsubstituted phenyl, said nanofluid and said channel being designed and constructed such that heat is carried by said nanostructures from a first end of said channel to a second end thereof.
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12. A composition comprising:
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(i) a discrete tubular, discrete spherical or discrete planar nanostructure being composed of a plurality of peptides, wherein each of said plurality of peptides includes no more than 4 amino acids and comprises Phe-Phe having substituted or unsubstituted phenyl; and (ii) an agent being attached to said discrete nanostructure.
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13. A method for inducing localized hyperthermia in a cell or tissue of an individual, the method comprising:
delivering a plurality of nanoshells, each having a discrete tubular, discrete spherical or discrete planar nanostructure core and a conductive shell and being capable of converting incident radiation into heat energy, said nanostructure core is composed of a plurality of peptides, each including no more than 4 amino acids and comprising Phe-Phe having substituted or unsubstituted phenyl; and
exposing said nanoshells to said incident radiation to thereby convert said incident radiation into said heat energy.
- 14. An electronic device comprising a source electrode, a drain electrode, a gate electrode and a channel, wherein at least one of said gate electrode and said channel comprises a discrete tubular, discrete spherical or discrete planar nanostructure being composed of a plurality of peptides each including no more than 4 amino acids and comprising Phe-Phe having substituted or unsubstituted phenyl.
- 17. A discrete tubular, discrete spherical or discrete planar nanostructure composed of a plurality of peptides each including no more than 4 amino acids and comprising Phe-Phe having substituted or unsubstituted phenyl.
Specification