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Ion sensor for long term use in complex medium

  • US 8,055,322 B2
  • Filed: 02/21/2008
  • Issued: 11/08/2011
  • Est. Priority Date: 07/30/2004
  • Status: Active Grant
First Claim
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1. A method for detecting ischemia comprising:

  • obtaining a differential electrical potential between an implanted electrode pair in a human body, the electrode pair including a first ion selective electrode (ISE) and a sodium ISE, wherein first ISE is a potassium ISE; and

    employing an implanted medical device to generate an indication of ischemia at least in part as a function of a change in the differential electrical potential over time, wherein the change is a rise in a ratio of potassium to sodium over time.

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