Medical biosensor by means of which biological liquids are analyzed

• US 8,057,740 B2
• Filed: 05/23/2005
• Issued: 11/15/2011
• Est. Priority Date: 06/23/2004
• Status: Expired due to Fees

• Current Assignee: Tesa SE (Maxingvest AG)
• Original Assignee: Tesa SE (Maxingvest AG)
• Inventors: Neubert, Ingo, Bunde, Bernd
• Primary Examiner(s): Sines, Brian J
• Application Number:
  US11/569,896
• Publication Number:
  US 20080199893A1
• Time in Patent Office: 2,367 Days
• Field of Search: 422/81, 422/100, 422/102
• US Class Current: 422/81
• CPC Class Codes: B32B 2250/03 3 layers
• CPC Class Codes: B32B 2250/24 All layers being polymeric
• CPC Class Codes: B32B 2255/10 on synthetic resin layer or on natural or synthetic rubber layer
• CPC Class Codes: B32B 2255/205 Metallic coating
• CPC Class Codes: B32B 2264/06 Vegetal particles
• CPC Class Codes: B32B 2307/542 Shear strength
• CPC Class Codes: B32B 2307/728 Hydrophilic
• CPC Class Codes: B32B 2535/00 Medical equipment, e.g. bandage, prostheses, catheter medical patches B32B2556/00
• CPC Class Codes: B32B 27/08 of synthetic resin
• CPC Class Codes: B32B 27/18 characterised by the use of special additives
• CPC Class Codes: B32B 27/304 comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
• CPC Class Codes: B32B 27/308 comprising acrylic (co)polymers
• CPC Class Codes: B32B 27/32 comprising polyolefins comprising vinyl (co)polymers or acrylic (co)polymers B32B27/30
• CPC Class Codes: B32B 27/36 comprising polyesters
• CPC Class Codes: B32B 27/365 comprising polycarbonates
• CPC Class Codes: B32B 3/266 characterised by an apertured layer, the apertures going through the whole thickness of the layer, e.g. expanded metal, perforated layer, slit layer regular cells B32B3/12
• CPC Class Codes: B32B 3/30 characterised by a layer formed with recesses or projections, e.g. hollows, grooves, protuberances, ribs apertured layer B32B3/266; layer with cavities or internal voids B32B3/26
• CPC Class Codes: B32B 5/142 Variation across the area of the layer
• CPC Class Codes: B32B 7/12 using interposed adhesives or interposed materials with bonding properties
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/2575 : Volumetric liquid transfer

Abstract

Medical biosensor by means of which biological liquids are analyzed, having at least three layers; a functional layer to which a contact adhesive strip, adhesive on both sided, is applied, and a structural film applied to the contact adhesive strip.

Claims

1. A medical biosensor by means of which biological fluids are analyzed, comprising at least three layers:

a functional layer comprising conductor tracks or being laminated to a conductive layer, and also comprising an enzyme or enzyme mixture, atop which there is a double-sidedly adhesive PSA tape comprising a measuring space, atop which there is a layer of structured film, said structured film having a continuous open channel embossed into the surface of the side facing said measuring space and running from said measuring space to an edge of the structured film, the shear strength of the adhesive on the pressure-sensitive adhesive tape at 25°

C. and 70°

C. under a weight load of 1000 g being greater than 10 000 min,

and the polymer or polymers of the adhesive having a K value of greater than 55 Pa*s, and

the structure depth of the structured film being 20 to 150 μ

m.

2. The medical biosensor of claim 1, wherein the adhesive is composed of one or more copolymers in which acrylate monomers form the principal constituent.

3. The medical biosensor of claim 1, wherein the polymers of the pressure-sensitive adhesive have a K value of greater than 60 Pa*s.

4. The medical biosensor of claim 1, wherein the microshear travel of the pressure-sensitive adhesive tape after 15 minutes at 40°

C. under a load of 500 g is less than 100 μ

m.

5. The medical biosensor of claim 1, wherein the ratio of the microshear travels, μ

S2/μ

S1, is less than 0.3.

6. The medical biosensor of claim 1, wherein the sum of the adhesive coatweight on the top and bottom sides of the pressure-sensitive adhesive tape is not more than 40 g/m².

7. The medical biosensor of claim 1, wherein the pressure-sensitive adhesive tape is composed of a carrier foil, which is coated on both sides with not more than 20 g/m² of a pressure-sensitive adhesive.

8. The medical biosensor of claim 1, wherein

the dynamic glass transition temperature of the adhesive at 10 rad/s is −

10°

C. to 15°

C.,

the adhesive contains no additions at all of tackifier resins or plasticizers, the bond strength of the adhesive to steel is at least 1.5 and/or

the bond strength of the adhesive to PET is at least 1.0 N/cm.

9. The medical biosensor of claim 1, wherein the structured film is selected from the group consisting of polyester, polyethylene, polypropylene, oriented polypropylene, polyvinyl chloride, polyacrylate, and polycarbonate and laminates or coextrudates thereof.

10. The medical biosensor of claim 1, wherein the thickness of the structured film is 25 μ

m to 150 μ

m.

11. The medical biosensor of claim 1, wherein the film is planarly structured.

12. The medical biosensor of claim 1, wherein a said continuous channel has a width of 20 to 60 μ

m and a depth of 20 to 60 μ

m.

13. The medical biosensor of claim 1, wherein the structured film is hydrophilically modified on one or both sides.

14. The medical biosensor of claim 7, wherein said carrier foil is polyester.

15. The medical biosensor of claim 1, wherein said channel extends perpendicularly to the measuring space.