Stents, stenting systems, and related methods for agent delivery
First Claim
1. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,a tubular member having a lumen there through to allow the passage of material;
- an outer membrane surrounding the tubular member, wherein at least a portion of the outer membrane is porous to the agent to allow the agent to be deposited on the site;
an inner member membrane attached to the tubular member, wherein the inner membrane is non-porous to the agent to be delivered to the site; and
a chamber located between the inner and outer membranes for holding the agent, wherein the agent in the chamber diffuses through the porous portion of the outer membrane and onto the body site;
wherein the outer membrane includes a longitudinal surface having at least three through-holes.
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Abstract
A stenting system for insertion into the lumen of a body duct or vessel for delivering a therapeutic agent to a treatment site on the duct or vessel. The stenting system includes an a tubular stent member having a lumen there through to allow the passage of material, an outer membrane attached to the stent at least a portion of which is porous to the therapeutic agent to allow the agent to pass to the treatment site, an inner membrane attached to the stent which is nonporous to the therapeutic agent to prevent the agent from entering the lumen of the stent, and a chamber located between the inner and outer membranes for holding the therapeutic agent. The therapeutic agent in the chamber may diffuse through the porous portion of the membrane and be deposited directly on the body site.
15 Citations
20 Claims
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1. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,
a tubular member having a lumen there through to allow the passage of material; -
an outer membrane surrounding the tubular member, wherein at least a portion of the outer membrane is porous to the agent to allow the agent to be deposited on the site; an inner member membrane attached to the tubular member, wherein the inner membrane is non-porous to the agent to be delivered to the site; and a chamber located between the inner and outer membranes for holding the agent, wherein the agent in the chamber diffuses through the porous portion of the outer membrane and onto the body site;
wherein the outer membrane includes a longitudinal surface having at least three through-holes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A system for insertion into a body lumen for delivering an agent to a site on the body lumen, the system comprising,
an inner tubular member having a lumen there through for the passage of material; -
a membrane surrounding the inner tubular member; and a porous outer tubular member surrounding the inner tubular member and the membrane, wherein the membrane and the porous outer tubular member define a chamber therebetween for holding the agent, wherein the agent in the chamber may pass through the porous outer tubular member and be deposited directly on the body site, and wherein the membrane is non-porous to the agent thereby isolating the lumen of the inner tubular member from the agent in the chamber;
wherein the porous outer tubular member includes a longitudinal surface having at least three through-holes. - View Dependent Claims (10, 11, 12, 13, 14, 15)
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16. A system for delivering an agent to a body site comprising:
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a tube having a lumen there through, wherein the sides of the tube have openings therein to allow passage of material through the lumen; an outer membrane surrounding the tube and forming a chamber with a surface of the tube, wherein at least a portion of the membrane is porous to the agent allowing diffusion of the agent there through to the body site, and wherein the tube prevents the agent from diffusing from the chamber and into the lumen of the tube; and an opening in the chamber allowing delivery of the agent to the chamber;
wherein the outer membrane includes a longitudinal surface having at least three though-holes. - View Dependent Claims (17, 18, 19, 20)
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Specification