Accommodating intraocular lens system with aberration-enhanced performance

• US 8,062,361 B2
• Filed: 08/01/2005
• Issued: 11/22/2011
• Est. Priority Date: 01/25/2001
• Status: Expired due to Fees

• Current Assignee: Visiogen, Inc. (Abbott Laboratories)
• Original Assignee: Visiogen, Inc. (Abbott Laboratories)
• Inventors: Evans, Scott, Portney, Valdemar, Nguyen, Tuan Anh, Zadno-Azizi, Gholam-Reza
• Primary Examiner(s): Willse; David H.
• Application Number:
  US11/195,422
• Publication Number:
  US 20050267575A1
• Time in Patent Office: 2,304 Days
• Field of Search: 623 632- 637
• US Class Current: 623/6.34
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/1627 for changing index of refraction, e.g. by external means or by tilting
• CPC Class Codes: A61F 2/1629 for changing longitudinal position, i.e. along the visual axis when implanted
• CPC Class Codes: A61F 2/1632 for changing radial position, i.e. perpendicularly to the visual axis when implanted
• CPC Class Codes: A61F 2/1648 Multipart lenses

Abstract

An accommodating intraocular lens implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power. The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power. The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.

Claims

1. An accommodating intraocular lens implantable in an eye, the lens comprising:

an anterior portion having an anterior biasing element and an anterior optic having refractive power; and

a posterior portion having a posterior biasing element and a posterior optic having refractive power;

the anterior optic and the posterior optic being relatively moveable generally along an optical axis of the eye in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens, the anterior optic and the posterior optic each having an optical axis;

the lens having an aberration-inducing force characteristic to allow aberration-inducing relative movement of the optical axes of the optics when the lens is in the eye to cause the optical axes to become non-colinear, thereby adding optical aberration to the lens which increases depth of focus of the lens.

2. The lens of claim 1, wherein the aberration-inducing relative movement comprises tilting movement of the anterior optic.

3. The lens of claim 1, wherein the aberration-inducing relative movement comprises decentration movement of the anterior optic.

4. The lens of claim 1, wherein the aberration-inducing relative movement comprises both tilting movement and decentration movement of the anterior optic.

5. The lens of claim 1, wherein the anterior biasing element has a cross-section with a relatively broad dimension oriented generally transverse to an optical axis, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

6. The lens of claim 1, wherein the anterior biasing element comprises a first translation member comprising a first arm and a second arm, each of said first arm and said second arm having a cross-section with a relatively broad dimension oriented generally transverse to the optical axis of the anterior optic, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

7. The lens of claim 6, wherein the anterior biasing element comprises a second translation member comprising a third arm and a fourth arm, each of said third arm and said fourth arm having a cross-section with a relatively broad dimension oriented generally transverse to the optical axis of the anterior optic when the anterior optic is not tilted, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

8. The lens of claim 1, wherein the anterior optic has a refractive power of +25 diopters or more.

9. The lens of claim 1, wherein the aberration-inducing force characteristic is about 70 mg to about 115 mg.

10. The lens of claim 1, wherein the optical axis of the anterior optic and the optical axis of the posterior optic are substantially coincident in the absence of external forces acting upon the lens.

11. An accommodating intraocular lens implantable in an eye having an optical axis, the lens comprising:

an anterior portion having an anterior biasing element and an anterior viewing element, the anterior viewing element comprising an optic having refractive power;

a posterior portion having a posterior viewing element;

the anterior biasing element attached to a periphery of the anterior viewing element at substantially diametrically opposed first and second attachment locations;

the periphery of the anterior viewing element being unattached to the anterior biasing element between the first and second attachment locations;

the size of the first and second attachment locations being sufficiently small such that an optical axis of the anterior optic tilts and/or decenters relative to the optical axis of the eye during movement of the anterior optic relative to the posterior viewing element generally along the optical axis of the eye under force applied by the ciliary body.

12. The lens of claim 11, further comprising a first retention member extending radially outwardly from the periphery of said anterior viewing element.

13. The lens of claim 12, further comprising a second retention member extending radially outwardly from the periphery of said anterior viewing element.

14. The lens of claim 13, wherein said first retention member is located angularly midway between said attachment locations, and said second retention member is located angularly midway between said attachment locations and substantially diametrically opposed from said first retention member.

15. The lens of claim 11, wherein said anterior biasing element is configured to contact the interior of the capsular bag of the eye along substantially the entire length of said anterior biasing element.

16. The lens of claim 11, wherein the anterior biasing element has a cross-section with a relatively broad dimension oriented generally transverse to the optical axis of the anterior optic when the anterior optic is not tilted, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

17. The lens of claim 11, wherein the anterior biasing element comprises a first translation member comprising a first arm and a second arm, each of said first arm and said second arm having a cross-section with a relatively broad dimension oriented generally transverse to the optical axis of the anterior optic when the anterior optic is not tilted, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

18. The lens of claim 17, wherein the anterior biasing element comprises a second translation member comprising a third arm and a fourth arm, each of said third arm and said fourth arm having a cross-section with a relatively broad dimension oriented generally transverse to the optical axis of the anterior optic when the anterior optic is not tilted, and a relatively narrow dimension oriented generally transverse to the relatively broad dimension.

19. The lens of claim 11, wherein:

the posterior portion further comprises a posterior biasing element attached to the posterior viewing element at third and fourth attachment locations;

the anterior portion and posterior portion meeting at first and second apices of the intraocular lens such that a plane passing through both apices is closer to one of the first attachment location and the third attachment location than to the other of the first attachment location and the third attachment location.

20. The lens of claim 11, wherein said anterior optic tilts by 2.5 degrees to 10 degrees relative to the optical axis of the eye during movement of the anterior optic relative to the posterior viewing element.

21. The lens of claim 11, wherein said anterior optic decenters by 0.25 mm to 1.0 mm relative to the optical axis of the eye during movement of the anterior optic relative to the posterior viewing element.

22. The lens of claim 11, wherein the size of the first and second attachment locations is sufficiently small such that the optical axis of the anterior optic both tilts and decenters relative to the optical axis of the eye during said relative movement.

23. The lens of claim 11, wherein the anterior biasing element is formed from a material having a Young'"'"'s modulus of about 300 P.S.I.

24. The lens of claim 11, wherein the anterior optic has a refractive power of +25 diopters or more.

25. The lens of claim 11, wherein the posterior viewing element comprises an optic having refractive power, and the optical axis of the anterior optic and an optical axis of the posterior optic are substantially coincident in the absence of external forces acting upon the lens.

26. An accommodating intraocular lens system comprising:

an anterior optic having a positive refractive power, said anterior optic having an anterior optical axis;

a posterior optic having a negative refractive power, said posterior optic having a posterior optical axis;

said optics mounted to move generally along an anterior-to-posterior direction relative to each other in response to ciliary muscle action, said optics having within their range of relative motion a first configuration in which said anterior optical axis is sufficiently misaligned relative to said posterior optical axis to introduce optical aberration in the lens that increases depth of focus relative to the depth of focus that would exist if said axes of said optics were aligned.

27. The lens system of claim 26, wherein said anterior optical axis is tilted relative to said posterior optical axis when said optics are in said first configuration.

28. The lens system of claim 27, wherein said anterior optical axis is tilted by 2.5 degrees to 10 degrees relative to said posterior optical axis when said optics are in said first configuration.

29. The lens system of claim 27, wherein said anterior optical axis is tilted by 5 degrees to 7.5 degrees relative to said posterior optical axis when said optics are in said first configuration.

30. The lens system of claim 26, wherein said anterior optical axis is decentered relative to said posterior optical axis when said optics are in said first configuration.

31. The lens system of claim 30, wherein said anterior optical axis is decentered by 0.25 mm to 1.0 mm relative to said posterior optical axis when said optics are in said first configuration.

32. The lens system of claim 30, wherein said anterior optical axis is decentered by 0.5 mm to 7.5 mm relative to said posterior optical axis when said optics are in said first configuration.

33. The lens system of claim 26, wherein said anterior optical axis is both tilted and decentered relative to said posterior optical axis when said optics are in said first configuration.

34. The lens system of claim 26, wherein the anterior optic has a refractive power of +25 diopters or more.

35. An accommodating intraocular lens implantable in an eye, the lens comprising:

an anterior portion having an anterior biasing element and an anterior optic having refractive power; and

a posterior portion having a posterior biasing element and a posterior optic having refractive power;

the anterior optic and the posterior optic being relatively moveable generally along an optical axis of the eye in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens, the anterior optic and the posterior optic each having an optical axis;

the lens having an aberration-inducing force characteristic to allow aberration-inducing relative movement of the optical axes of the optics when the lens is in the eye to create or increase axial offset and/or angular orientation of the optical axes relative to each other thereby adding optical aberration to the lens which increases depth of focus of the lens.