Device and method for multiple analyte detection
First Claim
Patent Images
1. A device comprising:
- a substrate;
a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, (iii) at least one sample delivery channel in fluid communication with the sample inlet, and (iv) a channel means providing fluid communication between the two or more detection chambers and the at least one sample delivery channel; and
detection reagents in the two or more detection chambers;
wherein (1) the substrate comprises two or more layers, a high thermal conductivity metal surface, and a plastic polymer on the high thermal conductivity metal surface, (2) each of the two or more detection chambers comprises an opaque lower wall that minimizes reflection, (3) each of the two or more detection chambers is at least partially defined by the plastic polymer, (4) the plastic polymer prevents corrosion of the high thermal conductivity metal surface, and (5) the plastic polymer separates the high thermal conductivity metal surface from each of the two or more detection chambers such that the high thermal conductivity metal surface does not contact the detection reagents.
7 Assignments
0 Petitions
Accused Products
Abstract
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
-
Citations
11 Claims
-
1. A device comprising:
-
a substrate; a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, (iii) at least one sample delivery channel in fluid communication with the sample inlet, and (iv) a channel means providing fluid communication between the two or more detection chambers and the at least one sample delivery channel; and detection reagents in the two or more detection chambers; wherein (1) the substrate comprises two or more layers, a high thermal conductivity metal surface, and a plastic polymer on the high thermal conductivity metal surface, (2) each of the two or more detection chambers comprises an opaque lower wall that minimizes reflection, (3) each of the two or more detection chambers is at least partially defined by the plastic polymer, (4) the plastic polymer prevents corrosion of the high thermal conductivity metal surface, and (5) the plastic polymer separates the high thermal conductivity metal surface from each of the two or more detection chambers such that the high thermal conductivity metal surface does not contact the detection reagents. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
Specification