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Methods of increasing platelet and hematopoietic stem cell production

  • US 8,067,367 B2
  • Filed: 09/18/2003
  • Issued: 11/29/2011
  • Est. Priority Date: 09/18/2002
  • Status: Expired due to Fees
First Claim
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1. A method of providing hematopoietic stem cells to a subject comprising the steps of:

  • administering a thrombopoietin (TPO) mimetic compound to a subject to increase stem cells in said subject;

    harvesting one or more of the stem cells;

    treating said subject with a bone marrow ablative treatment; and

    transplanting the harvested stem cells into the subject,wherein the TPO mimetic compound has the following sequence;

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