Method for recognizing and marking contrast agents in blood vessels of the lung with the aid of a CT examination and an image evaluation unit of a CT system

• US 8,068,578 B2
• Filed: 09/18/2008
• Issued: 11/29/2011
• Est. Priority Date: 09/28/2007
• Status: Expired due to Fees

• Current Assignee: Siemens Healthcare GMBH (Siemens AG)
• Original Assignee: Siemens AG
• Inventors: Krauss, Bernhard
• Primary Examiner(s): Glick; Edward
• Assistant Examiner(s): Taningco; Alexander H
• Application Number:
  US12/232,523
• Publication Number:
  US 20090086884A1
• Time in Patent Office: 1,167 Days
• Field of Search: 378/4, 378/5, 378/8, 378/98, 378/98.11, 378/98.12
• US Class Current: 378/5
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/4014 arranged in multiple source-detector units
• CPC Class Codes: A61B 6/4241 using energy resolving detectors, e.g. photon counting
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/482 involving multiple energy imaging
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: G01N 2223/612 biological material

Abstract

A method and an image evaluation unit are disclosed for recognizing and marking contrast agents in blood vessels of the lung with the aid of a CT examination using at least two different x-ray energy spectra. In at least one embodiment, the method includes scanning a patient at least in the region of the lung with two different x-ray energy spectra, with the patient having contrast agents in the blood stream; reconstructing an at least two or three dimensional tomographic display for each x-ray energy spectrum which reproduces the local spectrum-specific absorption properties of the scanned region, wherein a surrounding area is defined for a multiplicity of voxels for which an average ratio is calculated with the aid of the local absorption values of the at least two x-ray energy spectra, which surrounding area specifies a measure for the ratio of the proportion of contrast agent to the proportion of soft tissue in the surrounding area of the respectively considered voxel, and wherein, in the case of this ratio dropping below a threshold value, this voxel is considered to have reduced circulation and is marked in a tomographic display.

Claims

1. A method for recognizing and marking blood vessels of a lung with the aid of a CT examination using at least two different x-ray energy spectra, the method comprising:

scanning a patient, at least in a region of the lung, with two different x-ray energy spectra, with the patient having only a single contrast agent administered; and

reconstructing an at least two dimensional tomographic image for each x-ray energy spectrum which reproduces local spectrum-specific absorption properties of the scanned region, wherein

a surrounding area is defined for a multiplicity of voxels for which an average ratio is calculated with the aid of local absorption values of the at least two x-ray energy spectra, the average ratio representing a measure for a ratio of a proportion of the single contrast agent to a proportion of soft tissue in the surrounding area of the respectively considered voxel, and

upon the average ratio dropping below a threshold value, the respectively considered voxel is considered to have reduced blood circulation and is marked in the reconstructing at least two dimensional tomographic image.

2. The method as claimed in claim 1, wherein the average ratio is formed by local absorption values of the at least two x-ray energy spectra.

3. The method as claimed in claim 2, wherein a quotient of absorption coefficients determined by two x-ray energy spectra, respectively, is used as the average ratio.

4. The method as claimed in claim 2, wherein a quotient of HU values determined by two x-ray energy spectra, respectively, is used as the average ratio.

5. The method as claimed in claim 1, wherein:

material of the scanned region is decomposed for two different materials and two tomographic data records with equivalent densities of each of the two different materials are determined, and

a quotient of the equivalent densities of the two materials, respectively, determined by two x-ray energy spectra is used as the average ratio.

6. The method as claimed in claim 1, wherein:

material of the scanned region is decomposed into soft tissue and air on one hand, and the single contrast agent on the other, and at least one tomographic virtual native image, which displays the soft tissue and the air, and a tomographic contrast agent image, which displays the single contrast agent, are determined, and

the average ratio is formed with the aid of the tomographic virtual native image and the tomographic contrast agent image.

7. The method as claimed in claim 6, wherein the average ratio is based on the local absorption values of the contrast agent image X_I and of the local absorption values of the virtual native image X_Vn using the formula

8. The method as claimed in claim 6, wherein a quotient of equivalent density values of the contrast agent image and equivalent density values of the virtual native image is used as the average ratio.

9. The method as claimed in claim 1, wherein a linearly weighted absorption value is determined from reconstructed image data of the two x-ray energy spectra for each voxel of the scanned region before carrying out the defining of the surrounding area and the marking, wherein if a threshold value for a linearly weighted absorption value is exceeded and the method is carried out only for those voxels which exceed this threshold value.

10. The method as claimed in claim 1, wherein a linearly weighted absorption value is determined from reconstructed image data of the at least two x-ray energy spectra for each voxel of the scanned region before carrying out the defining of the surrounding area and the marking, wherein if a bounded range for the linearly weighted absorption value is adhered to and the method is carried out only for those voxels which lie in this bounded range.

11. The method as claimed in claim 1, wherein the defined surrounding area of a voxel comprises a preset radius.

12. The method as claimed in claim 11, wherein the preset radius is selected as a function of at least one of an observed vessel diameter, image noise occurring and possible motion unsharpness, with the preset radius increasing with increasing vessel diameter and increasing noise.

13. The method as claimed in claim 1, wherein the marked voxels are displayed in color.

14. The method of claim 1, wherein the average ratio is calculated through direct use of the local absorption values of the at least two x-ray energy spectra.

17. A non-transitory tangible computer readable medium including program segments for, when executed on a computer device, causing the computer device to implement the method of claim 1.

15. An image evaluation unit for a CT system comprising:

a processor; and

a program memory, the program memory including a program code where, after a scan of a patient, using the CT system, of at least the region of a lung with two different x-ray energy spectra, with the patient having only a single contrast agent administered, the program code executes the following when the image evaluation unit is operating;

reconstructing an at least two dimensional tomographic image for each x-ray energy spectrum which reproduces local spectrum-specific absorption properties of the scanned region;

defining a surrounding area for a multiplicity of voxels for which an average ratio is calculated with the aid of local absorption values of the at least two x-ray energy spectra, the average ratio representing a measure for a ratio of a proportion of the single contrast agent to a proportion of soft tissue in the surrounding area of the respectively considered voxel; and

displaying a tomographic display of the scanned region, with voxels being considered to have reduced blood circulation and marked as soon as the average ratio drops below a threshold value.

16. The image evaluation unit as claimed in claim 15, wherein the average ratio is formed by local absorption values of the at least two x-ray energy spectra.

18. A method for recognizing and marking blood vessels of the lung with the aid of a CT examination using at least two different x-ray energy spectra, the method comprising:

scanning a patient, at least in a region of the lung, with two different x-ray energy spectra, with the patient having only a single contrast agent administered;

reconstructing an at least two dimensional tomographic image for each x-ray energy spectrum which reproduces local spectrum-specific absorption properties of the scanned region;

defining a surrounding area for a multiplicity of voxels for which an average ratio is calculated with the aid of local absorption values of the at least two x-ray energy spectra, average ratio representing a measure for a ratio of a proportion of the single contrast agent to a proportion of soft tissue in the surrounding area of the respectively considered voxel; and

displaying a tomographic image of the scanned region, with voxels being considered to have reduced blood circulation and marked as soon as the average ratio drops below a threshold value.

19. A non-transitory tangible computer readable medium including program segments for, when executed on a computer device, causing the computer device to implement the method of claim 18.