System and method for regulating cardiopulmonary triggered therapy to the brain
First Claim
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1. An implantable medical device system for implantation in a patient, the system comprising:
- a biocompatible housing adapted to be implanted in a patient;
a brain monitoring element adapted to sense activity in a brain of the patient and generate a brain signal;
a respiratory monitoring element, the respiratory monitoring element adapted to sense respiratory activity and generate a respiratory signal, the respiratory monitoring element comprising a sensor stub;
a therapy module at least partially supported by the housing, the therapy module adapted to deliver a therapeutic output to the brain of the patient when a respiratory event is detected in the respiratory signal; and
a processor at least partially supported by the housing, the processor configured toreceive the respiratory signal from the respiratory monitoring element and detect a respiratory event in the respiratory signal,activate the therapy module to deliver the therapeutic output to the brain based on detecting a respiratory event in the respiratory signal;
receive the brain signal from the brain monitoring element and detect a neurological event in the brain signal;
determine whether a neurological event has been detected in the brain signal within a specified period of time after detection of the respiratory event; and
change the therapeutic output delivered by the therapy module based on the sensed brain activity that occurs following a detected respiratory event.
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Abstract
A medical device system includes a housing, the housing at least partially supporting a therapy module and a processor, and a respiratory monitoring element coupled to the processor. The processor is configured to activate the therapy module upon detection of a respiratory event in a respiratory signal. In some embodiments, the system may further comprise a brain monitoring element, and the processor may be configured to monitor a brain signal and change the therapeutic output based upon the brain signal.
169 Citations
46 Claims
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1. An implantable medical device system for implantation in a patient, the system comprising:
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a biocompatible housing adapted to be implanted in a patient; a brain monitoring element adapted to sense activity in a brain of the patient and generate a brain signal; a respiratory monitoring element, the respiratory monitoring element adapted to sense respiratory activity and generate a respiratory signal, the respiratory monitoring element comprising a sensor stub; a therapy module at least partially supported by the housing, the therapy module adapted to deliver a therapeutic output to the brain of the patient when a respiratory event is detected in the respiratory signal; and a processor at least partially supported by the housing, the processor configured to receive the respiratory signal from the respiratory monitoring element and detect a respiratory event in the respiratory signal, activate the therapy module to deliver the therapeutic output to the brain based on detecting a respiratory event in the respiratory signal; receive the brain signal from the brain monitoring element and detect a neurological event in the brain signal; determine whether a neurological event has been detected in the brain signal within a specified period of time after detection of the respiratory event; and change the therapeutic output delivered by the therapy module based on the sensed brain activity that occurs following a detected respiratory event. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. An implantable medical device system for implantation in a patient, the device comprising:
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a biocompatible housing adapted to be implanted in a patient; a respiratory monitoring element adapted to sense respiratory activity and generate a respiratory signal, the respiratory monitoring element comprising an electrode; a processor at least partially supported by the housing, the processor adapted configured to receive the respiratory signal from the respiratory monitoring element and detect a respiratory event; a therapy module at least partially supported by the housing, the therapy module adapted to deliver a therapeutic output when a respiratory event is detected by the processor; and a lead coupled to the therapy module for delivering the therapeutic output to a brain of the patient, the electrode being an integrated electrode at least partially supported by and disposed along the lead. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A medical device system, comprising:
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a biocompatible housing adapted to be implanted in a patient; a brain monitoring element adapted to sense activity in a brain of the patient and generate a brain signal; a respiratory monitoring element adapted to sense respiratory activity and generate a respiratory signal, the respiratory monitoring element comprising a sensor stub; therapy means for providing a therapeutic output to the brain of the patient; and a processor configured to receive the respiratory signal from the respiratory monitoring element, detect a respiratory event in the respiratory signal, activate the therapy means to provide the therapeutic output to the brain upon detection of a respiratory event, receive the brain signal from the brain monitoring element, detect a neurological event in the brain signal, determine whether a neurological event has been detected within a specified period of time after detection of the respiratory event, and change the therapeutic output provided by the therapy means based on the brain signal. - View Dependent Claims (42, 43, 44, 45, 46)
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Specification