Visual prosthesis for improved circadian rhythms and method of improving the circadian rhythms

• US 8,068,913 B2
• Filed: 12/01/2005
• Issued: 11/29/2011
• Est. Priority Date: 12/03/2004
• Status: Active Grant

• Current Assignee: Cortigent Incorporated, Doheny Eye Institute
• Original Assignee: Second Sight Medical Products, Inc. (Vivani Medical, Inc.)
• Inventors: Greenberg, Robert Jay, Humayun, Mark S.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): GHAND, JENNIFER LEIGH-STEWAR
• Application Number:
  US11/293,400
• Publication Number:
  US 20060173511A1
• Time in Patent Office: 2,189 Days
• Field of Search: 600/26, 600/27, 607/53, 607/54, 607/116, 607/141, 607/152, 607/88
• US Class Current: 607/54
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

Present invention is a method of improving circadian rhythms in blind people by stimulation the visual neural system. Ideally a retinal prosthesis of the type used to restore vision can be used to restore normal circadian rhythms. Additionally, brightness on the prosthesis can be increased in the morning and decreased in the evening to stimulate normal Circadian rhythms. Alternatively, if a retinal prosthesis is not preferable, the retina can be stimulated externally, during the day and not at night. While such eternal stimulation can not produced artificial vision, it can stimulate normal circadian rhythms.

Claims

1. A prosthesis comprising:

at least one electrode suitable for electrically stimulating visual neurons;

an electrical driver for applying a controlled electrical potential on said electrode; and

a control circuit including a timer for controlling activation of said electrical driver, wherein the timer is configured to control activation of the electrical driver at fixed time periods or predetermined intervals, said control circuit being configured to control said electrical driver in accordance with a time of day to apply said controlled electrical potential, in order to artificially stimulate circadian rhythms.

2. The prosthesis for stimulating circadian rhythms according to claim 1, wherein said control circuit is configured to increases intensity of said driver during morning hours.

3. The prosthesis for stimulating circadian rhythms according to claim 1, wherein said control circuit is configured to decrease intensity of said driver during evening hours.

4. The prosthesis for stimulating circadian rhythms according to claim 1, wherein said control circuit is configured to disable said driver during night time hours.

5. The prosthesis for stimulating circadian rhythms according to claim 1, wherein said control circuit is configured to allow a user to vary time based intensity patterns.

6. The prosthesis for stimulating circadian rhythms of claim 1 comprising at least one flexible circuit electrode array.

7. The prosthesis of claim 1, wherein the time of day is correlated with melatonin levels.

8. The prosthesis of claim 1, wherein the activation of said electrical driver controlled by the timer determines an electrical stimulation during the day and not at night.