Method and apparatus for distinguishing between clinically significant changes and artifacts in patient physiological information
First Claim
1. A patient physiological information monitoring system, comprising:
- a plurality of patient monitoring devices that monitor physiological information from a patient and generate corresponding physiological signals; and
a physiological information analyzer including one or more processors that processes the monitored physiological information and determines whether a physiological change is a clinically significant event or an artifact, the one or more processors being programmed to;
receive the physiological signals from the patient monitoring devices;
generate morphograms of one physiological signal versus another physiological signal from pairs of the received physiological signals within sampling intervals;
apply a wavelet decomposition to each morphogram to compute a signature for each mapping morphogram;
compare the morphogram signatures within and across the sampling intervals for a shape perturbation; and
determine whether the shape perturbation is a result of a clinically significant change or an artifact.
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Accused Products
Abstract
A patient physiological information monitoring system includes a plurality of patient monitoring devices (6) and a physiological information analyzer (2). The plurality of patient monitoring devices (6) monitor physiological information from a patient and generate corresponding physiological signals. The physiological information analyzer (2) processes the monitored physiological information and determines whether a physiological change is a clinically significant event or an artifact. The physiological information analyzer includes at least one receiver (4) that receives the physiological signals from the patient monitoring devices; a signal correlator (10) that generates morphograms from pairs of the received physiological signals; a signature generator (12) that applies a wavelet decomposition to each morphogram to compute a signature for each morphogram; and a decision component (14) that compares the morphogram signatures within and across sampling intervals and determines if a physiological change is a clinically significant change or an artifact.
14 Citations
20 Claims
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1. A patient physiological information monitoring system, comprising:
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a plurality of patient monitoring devices that monitor physiological information from a patient and generate corresponding physiological signals; and a physiological information analyzer including one or more processors that processes the monitored physiological information and determines whether a physiological change is a clinically significant event or an artifact, the one or more processors being programmed to; receive the physiological signals from the patient monitoring devices; generate morphograms of one physiological signal versus another physiological signal from pairs of the received physiological signals within sampling intervals; apply a wavelet decomposition to each morphogram to compute a signature for each mapping morphogram; compare the morphogram signatures within and across the sampling intervals for a shape perturbation; and determine whether the shape perturbation is a result of a clinically significant change or an artifact. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A patient physiological information monitoring system comprising:
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a plurality of patient monitoring devices that monitor physiological information from a patient and generate corresponding physiological signals; and a physiological information analyzer including one or more processors that processes the monitored physiological information and determines whether a physiological change is a clinically significant event or an artifact, the one or more processor being programmed to; receive the physiological signals sampled by the patient monitoring devices during successive sampling intervals; generate morphograms from pairs of the received physiological signals in each of the sampling intervals; compute a signature for each morphogram; and compare the morphogram signatures of a current and prior sampling intervals for a shape perturbation to determine if a physiological change is a clinically significant change or an artifact, wherein the sampling intervals occur at a sampling rate that is less than or equal to an alarm latency period of the corresponding patient monitor device, the alarm latency period corresponding to a time over which an alarm condition persists in order to trigger an alarm with a high degree of correctness. - View Dependent Claims (11, 12, 13)
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14. A method for determining whether a physiological change captured by a patient monitoring device is a clinically significant change or an artifact, comprising:
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receiving physiological signals captured by a patient monitoring device indicative of physiological information monitored from a patient; with one or more processors, generating a mapping of one physiological signal versus another physiological signal for pairs of the physiological signals as the physiological information for each sampling interval is received; with the one or more processors, applying a wavelet decomposition on each mapping to generate a signature for each mapping; with the one or more processors, comparing the mapping signatures within and across sampling intervals for signature perturbations; with the one or more processors, determining whether the signature perturbations are a result of a clinically significant change or an artifact; and with the one or more processors, in response to determining that the signature perturbations are the result of an artifact, overriding an alarm of the patient monitoring device; and with the one or more processors, in response to determining that the signature perturbations are the result of a clinically significant change, invoking the alarm of the patient monitoring device. - View Dependent Claims (15, 16, 17)
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18. A non-transitory computer readable medium having program code embodied therein that when executed by one or more processors, causes the one or more processor to perform a method comprising:
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receiving physiological signals captured by a patient monitoring device indicative of physiological information monitored from a patient; with one or more processors, generating a mapping of one physiological signal versus another physiological signal for pairs of the physiological signals as the physiological information for each sampling interval is received; with the one or more processors, applying a wavelet decomposition on each mapping to generate a signature for each mapping; with the one or more processors, comparing the mapping signatures within and across sampling intervals for signature perturbations; with the one or more processors, determining whether the signature perturbations are a result of a clinically significant change or an artifact; and with the one or more processors, in response to determining that the signature perturbations are the result of an artifact, overriding an alarm of the patient monitoring device; and with the one or more processors, in response to determining that the signature perturbations are the result of a clinically significant change, invoking the alarm of the patient monitoring device.
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19. A patient monitoring system, comprising:
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a patient monitoring device; a computer programmed to; generate morphogram signatures of related patient monitoring signals versus each other from the patient monitoring device; decompose the morphogram signatures using wavelet decomposition; compare changes in the decomposed morphogram signatures relative to each other or over time; and based on the morphogram signature comparisons, determine whether a clinically significant event or an artifact has occurred. - View Dependent Claims (20)
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Specification