Sample analyzer and sample analyzing method

• US 8,071,029 B2
• Filed: 03/27/2008
• Issued: 12/06/2011
• Est. Priority Date: 03/30/2007
• Status: Active Grant

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Wakamiya, Yuji, Okuzaki, Tomohiro, Takehara, Hisato
• Primary Examiner(s): Sines, Brian J
• Application Number:
  US12/079,798
• Publication Number:
  US 20080241937A1
• Time in Patent Office: 1,349 Days
• Field of Search: 422/50, 422/63, 422/64, 422/65, 422/66, 422/67, 422/81, 422/82.01, 422/82.05, 422/68.1, 436/43, 436/47, 436/54, 436/63, 436/66, 436/67, 436/68, 436/69, 436/70, 436/71, 436/174, 436/180
• US Class Current: 422/68.1
• CPC Class Codes: G01N 2035/00702 Curve-fitting; Parameter matching; Calibration constants
• CPC Class Codes: G01N 35/00693 Calibration
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/113332 with conveyance of sample along a test line in a container or rack
• CPC Class Codes: Y10T 436/119163 with aspirator of claimed structure
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

A sample analyzer and sample analyzing method perform following: a) mixing a sample with at least one of a first reagent and a second reagent, thereby preparing a measurement specimen; b) storing, in a memory, standard curve data corresponding to a reagent to be used in the step a) for preparing a measurement specimen; c) measuring the measurement specimen thereby obtaining measurement data; d) processing the measurement data based on the standard curve data, thereby obtaining an analysis result; and e) when the first, reagent and the second reagent are of the same type, determining a reagent to be used for the measuring between the first reagent and the second reagent, based on information regarding standard curve data stored in the memory.

Claims

1. A sample analyzer comprising:

a reagent container holder for holding a first reagent container accommodating a first reagent and a second reagent container accommodating a second reagent;

a measurement specimen preparer for mixing a sample with at least one of the first reagent and the second reagent, thereby preparing a measurement specimen;

a memory for storing standard curve data corresponding to a reagent to be used by the measurement specimen preparer for preparing a measurement specimen;

a measuring unit for measuring the measurement specimen thereby obtaining measurement data;

a processor; and

a non-transitory computer readable storage medium having stored therein data representing instructions executable by the processor, the storage medium including

a first set of instructions to process the measurement data based on the standard curve data, thereby obtaining an analysis result, and a second set of instructions to determine a reagent to be used for the measuring between the first reagent and the second reagent based on information regarding standard curve data stored in the memory when the first reagent and the second reagent are of the same type.

2. The sample analyzer according to claim 1, wherein second set of instructions determines the first reagent as a reagent to be used when standard curve data corresponding to the first reagent is stored in the memory, and standard curve data corresponding to the second reagent is not stored in the memory.

3. The sample analyzer according to claim 1, wherein

the first reagent container and the second reagent container each have an identifier, respectively;

the sample analyzer further comprises a reading unit for obtaining reagent identifying information by reading the identifier;

the memory stores the standard curve data in correspondence to the reagent identifying information of the reagent corresponding to the standard curve data; and

the second set of instructions determines whether the standard curve data corresponding to the reagent identified by the reagent identifying information corresponding to the first reagent container and the standard curve data corresponding to the reagent identified by the reagent identifying information corresponding to the second reagent container are stored in the memory when the first reagent and the second reagent are of the same type.

4. The sample analyzer according to claim 3, wherein the reagent identifying information includes a lot number of the reagent.

5. The sample analyzer according to claim 4, wherein the first set of instructions obtains the analysis result using common standard curve data with respect to measurement data obtained using the first reagent and measurement data obtained using the second reagent when the first reagent and the second reagent are of the same type and the lot numbers of the first reagent and the second reagent are the same.

6. The sample analyzer according to claim 1, wherein the second set of instructions determines usage order of the first reagent and the second reagent when the first reagent and the second reagent are of the same type.

7. The sample analyzer according to claim 6, wherein the second set of instructions determines the order so that the first reagent is used before the second reagent when standard curve data corresponding to the first reagent is stored in the memory and standard curve data corresponding to the second reagent is not stored in the memory.

8. The sample analyzer according to claim 6, further comprising a display for displaying a reagent list in which information related to the reagent is listed according to the usage order determined by the means second set of instructions.

9. The sample analyzer according to claim 1, wherein the storage medium further includes:

a third set of instructions to create the standard curve data;

a fourth set of instructions to accept validation of using the standard curve data created by the third set of instructions;

wherein

the memory stores the validated standard curve data when validation of the standard curve data is accepted by the fourth set of instructions.

10. The sample analyzer according to claim 1, further comprising a reagent information memory for storing reagent information for each reagent on the reagent holder, the reagent information comprising information indicating whether or not the standard curve data corresponding to the reagent is stored in the memory;

wherein

the second set of instructions determines the reagent to be used for the measuring between the first reagent and the second reagent based on the reagent information stored in the reagent information memory when the first reagent and the second reagent are of the same type.

11. The sample analyzer according to claim 1, further comprising a fifth set of instructions to manage expiration date of the reagent;

wherein

the second set of instructions determines the reagent to be used for the measuring between the first reagent and the second reagent based on expiration date of the first reagent and expiration date of the second reagent managed by the fifth set of instructions when the first reagent and the second reagent are of the same type.

12. The sample analyzer according to claim 1, further comprising a sixth set of instructions to manage remaining quantity of the reagent;

wherein

the second set of instructions determines the reagent to be used for the measuring between the first reagent and the second reagent based on remaining quantity of the first reagent and remaining quantity of the second reagent managed by the sixth set of instructions when the first reagent and the second reagent are of the same type.