Method and apparatus for treating subcutaneous histological features

• US 8,073,550 B1
• Filed: 08/14/2000
• Issued: 12/06/2011
• Est. Priority Date: 07/31/1997
• Status: Expired due to Fees

• Current Assignee: miraDry, Inc. (Sientra Incorporated)
• Original Assignee: Miramar Labs, Inc. (Sientra Incorporated)
• Inventors: Spertell, Robert Bruce
• Primary Examiner(s): ROBINSON, DANIEL LEON
• Application Number:
  US09/637,923
• Time in Patent Office: 4,131 Days
• Field of Search: 607/101, 607/100, 607/102, 607/115, 607/154, 607/156, 128/898, 606 9- 42
• US Class Current: 607/101
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2018/00005 Cooling or heating of the probe or tissue immediately surrounding the probe
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00035 with return means
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00458 Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61N 2005/007 for cooling the patient
• CPC Class Codes: A61N 5/025 Warming the body, e.g. hyperthermia treatment
• CPC Class Codes: A61N 5/04 Radiators for near-field treatment

Abstract

A system and method for treating subcutaneous histological features without affecting adjacent tissues adversely employs microwave energy of selected power, frequency and duration to penetrate subcutaneous tissue and heat target areas with optimum doses to permanently affect the undesirable features. The frequency chosen preferentially interacts with the target as opposed to adjacent tissue, and the microwave energy is delivered as a short pulse causing minimal discomfort and side effects. By distributing microwave energy at the skin over an area and adjusting power and frequency, different conditions, such as hirsuitism and telangiectasia, can be effectively treated.

Claims

1. A method of treating a targeted subcutaneous histological feature within a given depth range below a skin surface in the human body with microwave energy comprising the steps of selecting a microwave frequency in which the loss factor of the targeted subcutaneous histological feature is greater than the loss factor of tissue surrounding the targeted subcutaneous histological feature;

and directing microwave energy at the selected frequency into the skin with a power density and for a duration sufficient to raise the temperature of the feature to a level resulting in a permanent change in the pathology of the targeted subcutaneous histological feature due to interaction of the electric field of the microwaves with the targeted subcutaneous histological feature tissue without resulting in a permanent change in the pathology of the tissue surrounding the targeted subcutaneous histological feature.

2. The method as set forth in claim 1 above, including the step of spreading the microwave energy with a distributed energy throughout an area at the depth range of the targeted subcutaneous histological feature.

3. The method as set forth in claim 2 above, including the further step of cooling tissue between the skin surface and the targeted subcutaneous histological feature during at least a portion of the treatment.

4. The method as set forth in claim 1 above, wherein the targeted subcutaneous histological feature comprises hair and the interaction of the electrical field of the microwaves with the hair induces heating of the hair to cause permanent destruction of the follicles.

5. The method as set forth in claim 4 above, wherein the targeted subcutaneous histological feature comprises hair roots approximately 5 mm below the skin surface, and wherein the method further includes the step of controlling power density and duration of the microwave energy to radiate the targeted subcutaneous histological feature with 10 to 15 Joules of energy.

6. The method as set forth in claim 1 above, wherein the targeted subcutaneous histological feature comprises blood vessels of about 0.1 mm diameter or greater and located 2 mm or less below the skin surface, and wherein the microwave energy thromboses blood in the blood vessels by raising blood temperature to in excess of 55°

C.

7. The method as set forth in claim 6 above, wherein the microwave frequency is in a range of 10-20 GHz, the microwave energy is in a range of 20 to 30 Joules, and the duration is shorter than a time for thermal relaxation of blood vessels in the targeted subcutaneous histological feature.