Vibrator with a plurality of contact nodes for treatment of myocardial ischemia

• US 8,079,968 B2
• Filed: 05/23/2008
• Issued: 12/20/2011
• Est. Priority Date: 09/04/2003
• Status: Active Grant

• Current Assignee: Simon Fraser University
• Original Assignee: Ahof Biophysical Systems Inc.
• Inventors: Hoffmann, Andrew Kenneth
• Primary Examiner(s): Brown, Michael A.
• Application Number:
  US12/154,508
• Publication Number:
  US 20080275371A1
• Time in Patent Office: 1,306 Days
• Field of Search: 601/46, 601/48, 601/49, 601 55- 56, 601/77, 601148-152
• US Class Current: 601/46
• CPC Class Codes: A61B 17/225 for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
• CPC Class Codes: A61H 1/00 Apparatus for passive exercising A61H5/00 takes precedence; Vibrating apparatus driving means for vibrating A61H23/00; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones
• CPC Class Codes: A61H 2023/0209 powered with frequencies not related to mains frequency
• CPC Class Codes: A61H 2201/5043 Displays
• CPC Class Codes: A61H 2201/5061 Force sensors
• CPC Class Codes: A61H 31/00 Artificial respiration or heart stimulation, e.g. heart massage artificial respiration by treatment with gas or air, e.g. mouth-to-mouth respiration A61M16/00; applying electric currents by contact electrodes for stimulation, e.g. heart pace-makers A61N1/36 ; teaching or training models, demonstration models for medical purposes G09B23/288
• CPC Class Codes: A61H 31/005 with feedback for the user
• CPC Class Codes: A61H 31/006 Power driven
• CPC Class Codes: A61P 7/02 Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Abstract

A vibrator for use in enhancement of pre-hospital coronary thrombolysis comprising a vibration source operable to generate vibration at a frequency in the range of 1-1000 Hz with at least a pair of oscillatory contacts spaced to enable simultaneous seating to the anatomic left and right of the sternum (such as to match the geometry of the right and left coronary arteries) of a patient in need of coronary thrombolysis. The preferred vibrator is operable to emit vibration in the low frequency sonic range (at least 20 Hz) with an amplitude of about 1 mm-15 mm (and more preferably greater than 2 mm), such as to provide an effective transthoracic tool for acute coronary thrombolysis applications. In a variation, greater than a pair of contacts are utilized to provide oscillatory contact at differing intercostal space levels (in order to maximize vibratory penetration to the heart which is variably situated depending on the patient'"'"'s anatomy).

Claims

1. A non-invasive method of using a percussion device for treating a cardiac related ailment causing a state of low arterial blood flow within the thoracic cavity, comprising the steps of

a) providing a percussion device with a contact interface enabling engagement of at least a pair of contact nodes spaced to provide simultaneous seating to opposing sides of a bony structure upon the thoracic cavity of a human adult,

b) simultaneously engaging said at least a pair of contact nodes to opposing sides of a bony structure upon the thoracic cavity of a patient suffering from a cardiac related ailment causing a state of low arterial blood flow within the thoracic cavity, and

c) applying mechanical percussion via said at least a pair of contact nodes simultaneously engaged to said opposing sides of a bony structure upon the thoracic cavity of said patient at a frequency between 1-1000 Hz, and a stroke length in the range of 0.1 mm-10 mm at any time during step 1 (b),

whereby said applying mechanical percussion via said at least a pair of contact nodes simultaneously engaged to said opposing sides of a bony structure upon the thoracic cavity enables optimized localized acoustic transmission to the heart and coronary arteries thereupon in view to remediation of said cardiac related ailment causing said state of low arterial blood flow within said thoracic cavity of said patient.

2. The method of claim 1, whereby said percussion is delivered via said at least a pair of contact nodes at a stroke length of at least 1 mm.

3. The method of claim 2, wherein each of said at least a pair of contact nodes are sized and shaped to enable operative seating within a human rib space of an individual receiving percussion from said percussion device.

4. The method of claim 3, wherein said percussion device has greater than a pair of oscillatory contact nodes, wherein said greater than a pair of contact nodes are simultaneously applied to the anatomic left and right of the sternum at differing intercostal space levels.

5. The method of claim 2, wherein said at least a pair of contact nodes are adjustably spaced relative to one another.

6. The method of claim 2, wherein said at least a pair of contact nodes are simultaneously applied to a plurality of rib-spaces at differing intercostal space levels.

7. The method of anyone of claims 1 and 6 wherein said applying percussion is timed to cease during the systolic period of the cardiac cycle of said patient.

8. The method of claim 2, wherein said percussion device is sized and configured to enable hand held manoeuvring and engagement.

9. The method of claim 2, wherein said state of low arterial blood flow comprises a state of low coronary blood flow, whereby said percussion enhances coronary flow.

10. The method of claim 2, whereby said percussion device comprises a motor disposed within a housing enabling reciprocating motion of said at least a pair of contact nodes, whereby said at least a pair of contact nodes are mechanically linked to an active end of said motor and projected from said housing.

11. The method of claim 2, whereby said percussion device is enabled to track the electrical activity of the heart independent of an externally placed ECG monitor disposed remote from said percussion device.

12. The method of claim 1, wherein said at least a pair of contact nodes are engaged to at least one of the anterior chest wall anatomic left and right of the sternum, and the upper back anatomic left and right of the spine of said patient.

13. The method of claim 1, wherein said stroke length is at least 2 mm, and said frequency is in the range of 20 Hz to 120 Hz.

14. The method of claim 1, wherein an engagement force exerted upon said percussion device in application against said patient is measurable by a force meter.

15. The method of claim 1, wherein said cardiac related ailment comprises an acute thrombotic coronary obstruction, whereby said percussion enhances clearance of said acute thrombotic coronary obstruction.

16. The method of claim 1, wherein said state of low arterial blood flow relates to at least one of congestive heart failure and cardiogenic shock, whereby said percussion enhances left ventricular performance and thereby assists in remediating said at least one of congestive heart failure and cardiogenic shock.

17. The method of claim 1, wherein said contact interface is configured to enable a contoured fit to a chest wall surface receiving percussion following placement of said percussion device upon said chest wall surface.

18. The method of claim 1, whereby said percussion is delivered by a vibratory waveform comprising a lower frequency modulated upon a higher frequency.

19. The method of claim 1, whereby said percussion device enables selectable stroke length.

20. The method of claim 1, whereby vibration of an invasive region targeted by said percussion device is non-invasively confirmed at any point during step 1 (c), such as to ensure effective penetration of said percussion.

21. The method of claim 1, whereby the timing of the closure of the aortic valve is monitored by a non-invasive probe operable in conjunction with said percussion device , such as to enable verification of the timing of the end of systole of the cardiac cycle of said patient.

22. The method of claim 1, whereby said percussion device is applied with at least 50 newtons of engagement force by the hand of an operator, to ensure adequate transmission of said percussion.

23. A non-invasive emergency method for restoring coronary blood flow in a patient experiencing an acute coronary obstruction, comprising the steps of,

a) providing a vibrator with a contact interface disposing at least a pair of oscillatory contacts spaced to enable simultaneous seating to the anatomic left and right of the sternum of a patient suffering from an acute coronary obstruction, and

b) administering percussion at a frequency between 1-1000 Hz, and a stroke length in the range of 0.1 mm-10 mm to the chest wall, anatomic left and right of the sternum of said patient via said contacts,

whereby said percussion applied in concert to the anatomic left and right of the sternum enables optimized transmission to the heart and coronary arteries thereupon in view to remediation of said acute coronary obstruction.

24. The method of claim 23, whereby said percussion is delivered via said at least a pair of contacts at a stroke length of at least 1 mm.

25. The method of claim 24, wherein said contacts are sized and shaped to enable operative seating within a human rib-space, and are applied within the rib-spaces of said patient.

26. The method of claim 25, whereby said at least a pair of contacts are convexly shaped, such as to enhance fitted seating of said contacts within a ribspace.

27. The method of claim 24, wherein said contacts reciprocate back and forth in phase with one another during administration of said percussion.

28. The method of claim 23, wherein said percussion has a stroke length of greater than 2 mm, such as to ensure effective penetration of said percussion.

29. The method of anyone of claims 23, 25, and 28, wherein said percussion is timed to be turned off during the systolic period of the cardiac cycle of said patient.

30. The method of claim 23, whereby a plurality of ECG electrodes are disposed upon said contact interface of said vibrator, such as to enable an expedited means for tracking the heart rhythm through attainment of electrocardiographic information.

31. The method of claim 23, wherein an engagement force exerted upon said vibrator in application against said patient is measurable by a force meter operable in conjunction with said vibrator.

32. A non-invasive method of using a percussion device for delivering localized percussion to an external body surface generally overlying the heart of a patient in treatment of a heart attack, comprising the steps of,

a) providing a percussion device with a contact interface enabling engagement of at least a pair of contact nodes spaced to provide simultaneous seating to opposing sides of a bony structure upon the thoracic cavity of a human adult,

b) simultaneously engaging said at least a pair of contact nodes to opposing sides of a bony structure upon the thoracic cavity of a patient suffering from a heart attack

c) applying mechanical percussion via said at least a pair of contact nodes simultaneously engaged to said opposing sides of a bony structure upon said thoracic cavity at a frequency between 1-1000 impacts per second, and a stroke length in the range of 0.1 mm-10 mm, and

d) periodically halting said percussion during the systolic period of the cardiac cycle of said patient,

whereby said halting said percussion during the systolic period of the cardiac cycle assists in prevention of hemodynamic decay of said patient suffering from said heart attack, and said applying mechanical percussion via said at least a pair of contact nodes simultaneously engaged to said opposing sides of a bony structure overlying the thoracic cavity enable optimized transmission of the forces of said percussion to the heart and coronary arteries thereupon in view to treatment said heart attack.

33. The method of claim 32, whereby said percussion device delivers said percussion via said at least a pair of contact nodes at a stroke length of at least at least 1 mm.