Methods and devices for the delivery of therapeutic gases including nitric oxide
First Claim
1. A method of administering one or more therapeutic gases to an animal or human patient, comprising:
- providing at least one device comprising a reservoir that is capable of supplying the one or more therapeutic gases, an interface layer, made of a gas permeable material surrounding the reservoir, through which the gases must transit in order to reach the patient,and an element, covering all or some of the interface layer, that prevents the flow of therapeutic gases through the interface layer to the patient until the at least one device is activated, and that is selected from the group consisting of a sealing layer, a holding container, and combinations thereof;
activating the at least one device by compromising the element; and
allowing the one or more therapeutic gases to transit from the reservoir through the interface layer to the patient.
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Accused Products
Abstract
Gas packages for the delivery of therapeutic gases, and in particular gaseous nitric oxide (gNO) are provided herein. The gas packages comprise one or more of a gas reservoir, interface layer, sealing layer, and holding container. The interface layer regulates discharge of the therapeutic gas from the gas reservoir to the external environment. The sealing layer and/or holding container prevent evolution of the gas until the sealing layer is compromised or the holding container is opened. The gas packages and methods for using them are useful for the treatment, alleviation, and prevention of various disease and non-disease, medical and non-medical, conditions in humans and animals.
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Citations
15 Claims
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1. A method of administering one or more therapeutic gases to an animal or human patient, comprising:
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providing at least one device comprising a reservoir that is capable of supplying the one or more therapeutic gases, an interface layer, made of a gas permeable material surrounding the reservoir, through which the gases must transit in order to reach the patient, and an element, covering all or some of the interface layer, that prevents the flow of therapeutic gases through the interface layer to the patient until the at least one device is activated, and that is selected from the group consisting of a sealing layer, a holding container, and combinations thereof; activating the at least one device by compromising the element; and allowing the one or more therapeutic gases to transit from the reservoir through the interface layer to the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of treating or preventing disease and non-disease states in an animal or human patient, comprising administering one or more therapeutic gases to the patient by activating one or more gas package devices, wherein at least one gas package device comprises:
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a reservoir that is capable of supplying the one or more therapeutic gases; an interface layer, made of a gas permeable material surrounding the reservoir, that regulates the flow of the one or more therapeutic gases from the reservoir to an environment external to the at least one device; and an element, covering all or some of the interface layer, that prevents the flow of therapeutic gases through the interface layer to the external environment until the at least one device is activated by compromising the element, and that is selected from the group consisting of a sealing layer, a holding container, and combinations thereof. - View Dependent Claims (12, 13, 14, 15)
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Specification