Stent delivery for bifurcated vessels

• US 8,080,048 B2
• Filed: 03/30/2004
• Issued: 12/20/2011
• Est. Priority Date: 12/03/2001
• Status: Active Grant

• Current Assignee: JW Medical Systems Ltd
• Original Assignee: XTENT, Inc.
• Inventors: Andreas, Bernard, Grainger, Jeffry J.
• Primary Examiner(s): Houston, Elizabeth
• Application Number:
  US10/814,593
• Publication Number:
  US 20040249434A1
• Time in Patent Office: 2,821 Days
• Field of Search: 623 111- 154, 623/903, 606/108, 606/194
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/825 having longitudinal struts
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0071 breakable or frangible
• CPC Class Codes: A61F 2250/0097 Visible markings, e.g. indicia

Abstract

Apparatus and methods for delivering stents to bifurcated vessels involve delivering a first stent in a main branch of a vessel using a stent delivery catheter and delivering a second stent in a side branch of the vessel, without removing the stent delivery catheter from the patient. In various embodiments, multiple stents may be placed in either or both of the main and side branches. In some embodiments, stents in main and side branches are separate and do not touch, while in other embodiments a side branch stent may extend through a sidewall opening in a main branch stent. Stent length may optionally be adjusted in situ, and some embodiments provide for predilatation of one or more lesions.

Claims

1. A method of treating one or more lesions in a vessel, the vessel having a main branch and a side branch branching from the main branch at a bifurcation, the main branch having a lesion with a length, the method comprising:

providing a delivery catheter having an expandable member and a plurality of stent segments disposed on the delivery catheter and axially positionable over the expandable member, the plurality of stent segments comprising a first, a second, and a third stent segment, wherein each of the plurality of stent segments when unexpanded are in direct contact with but not fixedly attached to respective adjacent stent segments, each of the plurality of stent segments are capable of being individually and fully expanded, and each of the plurality of stent segments together with respective adjacent segments are capable of being simultaneously expanded;

positioning the delivery catheter in the main branch;

selecting a length of a first stent according to the length of the lesion to be treated in the main branch;

adjusting the length of the first stent according to the selected length while the delivery catheter remains in the vessel, wherein adjusting the length comprises selecting a first group of adjacent segments from the plurality of stents segments, wherein the first group includes at least the first and second stent segments;

axially separating the first stent from a second stent when unexpanded so that the first and second stent are separately deployable, the second stent comprising at least the third stent segment;

radially expanding the expandable member thereby radially expanding the first stent, wherein expanding the first stent comprises concurrently expanding the first group in the main branch while the second stent remains undeployed on the delivery catheter;

positioning the delivery catheter in the side branch; and

radially expanding the expandable member thereby radially expanding the second stent in the side branch, and

wherein the delivery catheter remains in the vessel between radially expanding the first and second stents.

2. A method as in claim 1 wherein the plurality of stents comprise a fourth stent segment, the method further comprising deploying the fourth stent segment from the delivery catheter in the main branch or the side branch without removing the delivery catheter from the vessel.

3. A method as in claim 1 wherein the first stent comprises a plurality of circumferentially and longitudinally arranged openings in a sidewall thereof, each opening of the plurality expandable to allow the deployment of a stent therethrough, the method further comprising:

positioning the delivery catheter through one of the openings; and

deploying a stent with the delivery catheter positioned through the one opening.

4. A method as in claim 3, wherein each of the plurality of openings are expandable to a diameter substantially equal to an expanded diameter of at least one of the first, second, or third stent segments when deployed in the vessel.

5. A method as in claim 1 wherein the second stent comprises a plurality of separable stent segments.

6. A method as in claim 5, wherein the selected length of the first stent is sufficient to allow the first stent to substantially traverse the lesion in the main branch;

and further comprising;

selecting a length of the second stent according to the length of a lesion in the side branch;

adjusting the length of the second stent according to the selected length of the second stent while the delivery catheter remains in the vessel, wherein adjusting the length comprises selecting a second group of adjacent segments from the plurality of stents segments, wherein the second group includes at least the third stent segment and an adjacent stent segment,

wherein the first stent and second stent comprise a different number of stent segments.

7. A method as in claim 6, wherein the step of adjusting the length of the first or second stent comprises moving a sheath disposed at least partially over the delivery catheter.

8. A method as in claim 6, wherein the step of adjusting the length of the first or second stent comprises moving a pusher tube disposed at least partially over the delivery catheter.

9. A method as in claim 1 wherein the first stent has a different overall length than the second stent.

10. A method as in claim 1 wherein the first stent is deployed before the second stent.

11. A method as in claim 1 wherein the second stent is deployed before the first stent.

12. A method as in claim 1 wherein the first and second stent each has a portion in the main branch.

13. A method as in claim 1 further comprising

adjusting the length of the second stent before deploying the second stent while the delivery catheter remains in the vessel, wherein adjusting the length comprises selecting a second group of adjacent segments from the plurality of stents segments, wherein the second group includes at least the third stent segment and an adjacent stent segment.

14. A method as in claim 1 further comprising

dilating at least one lesion in the vessel using the expandable member on the delivery catheter without a stent disposed thereon before deploying at least one of the first and second stents.

15. A method of treating one or more lesions in a vessel, the vessel having a first branch and a second branch meeting at a bifurcation, the first branch having a lesion with a length, the method comprising:

providing a delivery catheter having an expandable member and a plurality of stents disposed on the delivery catheter and axially positionable over the expandable member, the plurality of stent segments comprising a first, a second, and a third stent segment, each of the plurality of stent segments when unexpanded are in direct contact with but not fixedly attached to respective adjacent stent segments, wherein each of the plurality of stent segments are capable of being individually expanded, and each of the plurality of stent segments together with respective adjacent segments are capable of being simultaneously expanded;

positioning the delivery catheter in the first branch;

selecting a length of a first stent according to the length of the lesion to be treated in the first branch;

adjusting the length of the first stent according to the selected length while the delivery catheter remains in the vessel, wherein adjusting the length comprises selecting a first group of adjacent segments from the plurality of stents segments, wherein the first group includes at least the first and second stent segments;

axially separating the first stent from a second stent when unexpanded so that the first and second stent are separately deployable, the second stent comprising at least the third stent segment;

radially expanding the expandable member thereby radially expanding the first stent, wherein expanding the first stent comprises concurrently expanding the first group in the first branch, a portion of the first group being disposed across the bifurcation while the second stent remains undeployed on the delivery catheter;

positioning the delivery catheter in the second branch through an opening in a sidewall of the first stent; and

radially expanding the expandable member thereby radially expanding the second stent, and wherein at least a portion of the third stent segment is disposed in the second branch,

wherein the delivery catheter remains in the vessel between radially expanding the first and second stents.

16. The method of claim 15 further comprising dilating the opening in the sidewall of the first stent by expanding the expandable member on the delivery catheter.

17. The method of claim 16 wherein before dilating, the opening in the sidewall of the first stent is I-shaped.

18. The method of claim 15 wherein the first stent has a first portion with a plurality of first sidewall slots and a second portion with a plurality of second sidewall slots, the first slots being larger than the second slots.

19. The method of claim 18 wherein the opening in the sidewall of the first stent comprises one of the first slots, and wherein the first stent is deployed so that at least one of the first slots is aligned with the bifurcation.

20. The method of claim 15 wherein the first stent has a different geometry than the second stent.

21. The method of claim 15 wherein the first stent has a different length than the second stent.

22. The method of claim 15 wherein the second stent comprises a plurality of separable stent segments.

23. A method as in claim 22, wherein the selected length of the first stent is sufficient to allow the first stent to substantially traverse the lesion in the first branch, and the method further comprises:

selecting a length of the second stent according to the length of a lesion in the second branch;

adjusting the length of the second stent according to the selected length of the second stent while the delivery catheter remains in the vessel, wherein adjusting the length comprises selecting a second group of adjacent segments from the plurality of stents segments, wherein the second group includes at least the third stent segment and an adjacent stent segment,

wherein the first stent and second stent comprise a different number of stent segments.

24. A method as in claim 23, wherein the step of adjusting the length of the first or second stent comprises moving a sheath disposed at least partially over the delivery catheter.

25. A method as in claim 23, wherein the step of adjusting the length of the first or second stent comprises moving a pusher tube disposed at least partially over the delivery catheter.

26. The method of claim 15 wherein the first stent comprises a plurality of circumferentially and longitudinally arranged sidewall openings, each opening of the plurality expandable to allow the deployment of a stent therethrough and at least one opening of the plurality of openings is aligned with the first branch of the vessel, the method further comprising expanding the at least one expandable opening using the expandable member on the delivery catheter without a stent disposed thereon.

27. A method as in claim 26, wherein each of the plurality of openings are expandable to a diameter substantially equal to an expanded diameter of at least one of the first, second, or third stent segments when deployed in the vessel.