Injection device with internal dose indicator

• US 8,083,711 B2
• Filed: 10/20/2005
• Issued: 12/27/2011
• Est. Priority Date: 10/21/2004
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Enggaard, Christian Peter
• Primary Examiner(s): Lucchesi, Nicholas D
• Assistant Examiner(s): FLICK, JASON E
• Application Number:
  US11/665,485
• Publication Number:
  US 20080188797A1
• Time in Patent Office: 2,259 Days
• Field of Search: 604/68
• US Class Current: 604/68
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31553 without axial movement of dose setting member
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

The present invention relates to an injection device comprising a housing, a resilient member adapted to provide a force in the axial direction of the injection device for ejecting a dose from the injection device. The injection device further comprises a dose setting member operatively connected to a dose indicator barrel positioned within the housing, the dose setting member and the dose indicator barrel being movable relative to each other and cooperating to set the dose to be ejected from the injection device. The dose indicator barrel undergoes, during dose setting, a combined rotational and translational movement within the housing and relative to the housing.

Claims

1. An injection device (1) comprising a housing (8),

a piston rod that is separate element distinct from the housing and wherein the piston rod moves relative to the housing;

a resilient member (7) adapted to provide a force in the axial direction of the injection device (1), the force being necessary for ejecting a dose from the injection device (1), and

a dose setting member (2) operatively connected to a dose indicator barrel (4) positioned within the housing (8), the dose setting member (2) and the dose indicator barrel (4) being movable relative to each other and cooperating to set the dose to be ejected from the injection device (1), the

dose indicator barrel (4) engaging a threaded portion of the housing (8), wherein the dose indicator barrel (4), both during dose setting and during injection, is adapted undergo a combined rotational and translational movement within the housing (8) and relative to the housing (8).

a dose setting member (2) operatively connected to a dose indicator barrel (4) positioned within the housing (8), the dose setting member (2) and the dose indicator barrel (4) being movable relative to each other and cooperating to set the dose to be ejected from the injection device (1), the dose indicator barrel (4) engaging a threaded portion of the housing (8),

wherein the dose indicator barrel (4), during dose setting, is adapted undergo a combined rotational and translational movement within the housing (8) and relative to the housing (8).

2. An injection device (1) according to claim 1, wherein the dose setting member (2) engages the dose indicator barrel (4), the injection device (1) further comprising

a piston rod (5) having a threaded outer surface with a drive track (21) arranged in a longitudinal direction of the outer surface of the piston rod (5),

a drive member (6) engaging at least part of the drive track (21) of the piston rod (5) and having a threaded inner surface (10) cooperating with a threaded portion (9) arranged on an outer surface of the dose indicator barrel (4), the drive member (6) being adapted to drive and rotate with the piston rod (5) during ejection of a dose from the injection device (1)

wherein the housing (8) has a threaded portion (14) cooperating with the threaded outer surface of the piston rod (5) so that rotation of the piston rod (5) results in an axial movement of the piston rod (5).

3. An injection device (1) according to claim 1, wherein the dose setting member (2) engages the dose indicator barrel (4), the injection device (1) further comprising

a piston rod (5) having a threaded outer surface with a track arranged in a longitudinal direction of the outer surface of the piston rod (5),

a drive member (6) having a threaded portion cooperating with the threaded outer surface of the piston rod (5), and having a threaded inner surface (10) cooperating with a threaded portion (9) arranged on an outer surface of the dose indicator barrel (4), the drive member (6) being adapted to rotate relative to the piston rod (5) during ejection of a dose from the injection device,

wherein the housing (8) engages at least part of the track of the piston rod (5) so that rotation of the drive member (6) results in an axial movement of the piston rod (5).

4. An injection device (1) according to claim 1, further comprising

a piston rod (5) having a threaded outer surface with a drive track (21) arranged in a longitudinal direction of the outer surface of the piston rod (5),

a resilient member housing being at least partly defined by the dose indictor barrel (4) in combination with a main member (15), the dose indicator barrel (4) and the main member (15) being movable in relation to each other, the main member (15) having a threaded portion cooperating with the threaded outer surface of the piston rod (5),

a drive member (6) operatively connected to the main member (15) via a toothing (19) so that the drive member (6) is movable in relation to the main member (15) during dose setting but rigidly connected to the main member (15) during ejection of a dose from the injection device, the drive member (6) engaging at least part of the drive track (21) on the outer surface of the piston rod (5),

wherein the housing (8) has a threaded portion (14) cooperating with the threaded outer surface of the piston rod (5) so that rotation of the piston rod (5) by the drive member (6) results in an axial movement of the piston rod (5).

5. An injection device according to claim 4, further comprising an intermediate part (16) engaging the dose setting member (2) and the main member (15) of the resilient member housing, the intermediate part (16) being adapted to provided a biasing force to the drive member (6) in a direction towards the toothing (19).

6. An injection device (1) according to claim 1, further comprising

a piston rod (5) having a threaded outer surface with a drive track (21) arranged in a longitudinal direction of the outer surface of the piston rod (5),

a resilient member housing being at least partly defined by the dose indictor barrel (4) and a main member (15),

a drive member (6) operatively connected to the main member (15) via a toothing (19) in such a way that the drive member (6) is movable in relation to the main member (15) during dose setting but rigidly connected to the main member (15) during ejection of a dose from the injection device, the drive member (6) having threaded portion cooperating with the threaded outer surface of the piston rod (5),

wherein the housing (8) engages at least part of the track of the piston rod (5) so that rotation of the drive member (6) results in an axial movement of the piston rod (5).

7. An injection device according to claim 2, further comprising a locking member (11) adapted to fixate the piston rod (5) in such a way that no relative rotation of the piston rod (5) and the housing (8) is possible when the locking member (11) is in its locking position.

8. An injection device according to claim 7, further comprising a release button adapted for releasing the locking member (11) from its locking position.

9. An injection device according to claim 8, wherein the release button is positioned in the distal half of the length of the injection device.

10. An injection device according to claim 3, further comprising a locking member (11) adapted to fixate the drive member (6) in such a way that no relative rotation of the drive member (6) and the housing (8) is possible when the locking member (11) is in its locking position.

11. An injection device according to claim 10, further comprising a release button adapted for releasing the locking member (11) from its locking position, the release button being adapted to be released by a user of the injection device.

12. An injection device according to claim 11, wherein the release button is positioned in the distal half of the length of the injection device.

13. An injection device according to claim 1, wherein the resilient member (7) comprises a helical spring arranged coaxially with the piston rod (5).

14. An injection device (1) comprising

a housing (8),

a piston rod for moving axial with respect to the housing, the piston rod being a separate element from the housing, the piston rod being adapted to act upon a cartridge and expel medication from the cartridge;

a resilient member (7) adapted to provide a force in the axial direction of the injection device (1), the force being necessary for ejecting a dose from the injection device (1), and

a dose setting member (2) operatively connected to a dose indicator barrel (4) positioned within the housing (8), the dose setting member (2) and the dose indicator barrel (4) being movable relative to each other and cooperating to set the dose to be ejected from the injection device (1), the dose indicator barrel (4) threadedly engaging a threaded portion of the housing (8), wherein the dose indicator barrel may be rotate with respect to the threaded portion of the housing and wherein threaded engagement between the threaded portion of the hosing and the dose indicator barrel causes the dose indicator barrel to translate with respect to the housing when it is rotated the rotation causes the dose indicator,

wherein the dose indicator barrel (4), during dose setting, is adapted undergo a combined rotational and translational movement within the housing (8) and relative to the housing (8).