Method for efficient collection and storage of experimental data
First Claim
1. A method of storing experimental data on a computer system, comprising the steps of:
- collecting a plurality of image data and a plurality of feature data from each of a plurality of sub-containers in a container, each sub-container having a biological specimen disposed therein or thereon;
creating a first database, wherein the first database includes links to other databases, and wherein the first database is used as a pass-through database by a display application to view data collected from the container;
creating a first entry in the first database linking the first database to a second database, wherein the second database includes;
configuration data used to collect data from the container,summary data for the container calculated from the plurality of sub-containers, andsummary data for the sub-containers calculated from the plurality of image data and plurality of feature data, wherein the summary data for the sub-containers is organized in a plurality of tables, each table corresponding to a different one of the sub-containers; and
creating a plurality of second entries in the first database linking the first database to a plurality of third databases, wherein each third database includes a portion of the plurality of image data and the plurality of feature data collected from the plurality of sub-containers, and wherein the image and feature data for each third database is organized in a plurality of tables.
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Accused Products
Abstract
Methods and system for efficient collection and storage of experimental data allow experimental data from high-throughput, feature-rich data collection systems, such as high-throughput cell data collection systems to be efficiently collected, stored, managed and displayed. The methods and system can be used, for example, for storing, managing, and displaying cell image data and cell feature data collected from microplates including multiple wells and a variety of bio-chips in which an experimental compound has been applied to a population of cells. The methods and system provide a flexible and scalable repository of experimental data including multiple databases at multiple locations including pass-through databases that can be easily managed and allows cell data to be analyzed, manipulated and archived. The methods and system may improve the identification, selection, validation and screening of new drug compounds that have been applied to populations of cells.
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Citations
16 Claims
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1. A method of storing experimental data on a computer system, comprising the steps of:
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collecting a plurality of image data and a plurality of feature data from each of a plurality of sub-containers in a container, each sub-container having a biological specimen disposed therein or thereon; creating a first database, wherein the first database includes links to other databases, and wherein the first database is used as a pass-through database by a display application to view data collected from the container; creating a first entry in the first database linking the first database to a second database, wherein the second database includes; configuration data used to collect data from the container, summary data for the container calculated from the plurality of sub-containers, and summary data for the sub-containers calculated from the plurality of image data and plurality of feature data, wherein the summary data for the sub-containers is organized in a plurality of tables, each table corresponding to a different one of the sub-containers; and creating a plurality of second entries in the first database linking the first database to a plurality of third databases, wherein each third database includes a portion of the plurality of image data and the plurality of feature data collected from the plurality of sub-containers, and wherein the image and feature data for each third database is organized in a plurality of tables. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A computer readable medium having stored therein instructions for causing a central processing unit to execute a method of:
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collecting a plurality of image data and a plurality of feature data from each of a plurality of sub-containers in a container, each sub-container having a biological specimen disposed therein or thereon; creating a first database, wherein the first database includes links to other databases, and wherein the first database is used as a pass-through database by a display application to view data collected from the container; creating a first entry in the first database linking the first database to a second database, wherein the second database includes; configuration data used to collect data from the container, summary data for the container calculated from the plurality of sub-containers, and summary data for the sub-containers calculated from the plurality of image data and plurality of feature data, wherein the summary data for the sub-containers is organized in a plurality of tables, each table corresponding to a different one of the sub-containers; and creating a plurality of second entries in the first database linking the first database to a plurality of third databases, wherein each third database includes a portion of the plurality of image data and the plurality of feature data collected from the plurality of sub-containers, and wherein the image and feature data for each third database is organized in a plurality of tables.
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Specification