Post-biopsy cavity treatment implants and methods
First Claim
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1. A post-biopsy cavity treatment implant, comprising:
- at least one radiopaque element;
a core portion coupled to the at least one radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, the core portion including at least one of a polylactide (PLA), a polyglycolide (PGA), a poly(lactide-co-glycolide) (PLGA) and a polyglyconate, anda collagenous shell portion coupled to the core portion, the collagenous shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
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Abstract
A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
75 Citations
30 Claims
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1. A post-biopsy cavity treatment implant, comprising:
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at least one radiopaque element; a core portion coupled to the at least one radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, the core portion including at least one of a polylactide (PLA), a polyglycolide (PGA), a poly(lactide-co-glycolide) (PLGA) and a polyglyconate, and a collagenous shell portion coupled to the core portion, the collagenous shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A method of treating a cavity created by a percutaneous excisional procedure carried out through an incision, comprising the steps of:
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providing a post-procedure cavity implant, the post-procedure cavity implant including a radiopaque element;
a core portion coupled to the radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, and a shell portion coupled to the core portion, the shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture;implanting the post-procedure cavity implant into the cavity, and closing the incision.
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30. A method of treating a cavity created by an excisional procedure, comprising the steps of:
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selecting a first biodegradation rate range; selecting a second biodegradation rate range that is different from the first biodegradation rate range; providing a post-procedure cavity implant, the post-procedure cavity implant including a radiopaque element;
a core portion coupled to the radiopaque element, the core portion being configured to biodegrade at a first effective rate within the first biodegradation rate range, and a shell portion coupled to the core portion, the shell portion being configured to biodegrade at a second effective rate within the second biodegradation rate range, andimplanting the post-procedure cavity implant within the cavity.
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Specification