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Prevention and treatment of synucleinopathic and amyloidogenic disease

  • US 8,092,801 B2
  • Filed: 02/25/2008
  • Issued: 01/10/2012
  • Est. Priority Date: 02/23/2007
  • Status: Active Grant
First Claim
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1. A method of treating, reducing the risk of, lessening the severity of, or delaying the outset of a disease characterized by Lewy bodies or alpha-synuclein aggregation in the brain, the method comprising administering to a patient having or at risk of the disease an effective regime of an antibody that specifically binds to an epitope within residues 118-126 of intact human alpha-synuclein, residues being numbered according to SEQ ID NO:

  • 1.

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