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Apparatus and method for encapsulating pancreatic cells

  • US 8,093,038 B2
  • Filed: 09/17/2007
  • Issued: 01/10/2012
  • Est. Priority Date: 09/17/2007
  • Status: Expired due to Fees
First Claim
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1. An apparatus for coating micron-sized or sub-micron-sized particles, comprising:

  • an encapsulation chamber including a first fluid layer of either water or an aqueous solution, the first fluid layer disposed on a second fluid layer of a fluid incompatible with the first layer;

    a particle feed tube including a particle passage in combination with a feed tube opening at a discharge end of the particle feed tube, the feed tube opening disposed in the first fluid layer;

    a particle feed device in communication with an end of the particle passage opposite the feed tube opening, the particle feed device comprising a particle discharge channel having a particle discharge channel opening in combination with the end of the particle passage, and a polymer solution injection channel having an injection channel opening in combination with the end of the particle passage;

    a particle withdrawal tube including a first end in combination with the encapsulation chamber and connected at a second end to a filtration device; and

    a valveless pump connected to the particle withdrawal tube between the first end and the second end.

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