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Tumor necrosis factor-gamma

  • US 8,093,363 B2
  • Filed: 09/10/2010
  • Issued: 01/10/2012
  • Est. Priority Date: 11/07/1994
  • Status: Expired due to Fees
First Claim
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1. An isolated antibody or fragment thereof that specifically binds to a protein selected from the group consisting of:

  • (a) a protein whose amino acid sequence consists of amino acid residues −

    27 to 147 of SEQ ID NO;

    2;

    (b) a protein whose amino acid sequence consists of amino acid residues −

    26 to 147 of SEQ ID NO;

    2;

    (c) a protein whose amino acid sequence consists of amino acid residues 1 to 147 of SEQ ID NO;

    2;

    (d) a protein whose amino acid sequence consists of amino acid residues 25 to 147 of SEQ ID NO;

    2;

    (e) a protein whose amino acid sequence consists of a portion of SEQ ID NO;

    2, wherein said portion is at least 30 contiguous amino acid residues in length;

    (f) a protein whose amino acid sequence consists of a portion of SEQ ID NO;

    2, wherein said portion is at least 50 contiguous amino acid residues in length;

    (g) a protein whose sequence consists of the amino acid sequence of the full-length polypeptide encoded by the cDNA contained in ATCC™

    Deposit Number 75927;

    (h) a protein whose sequence consists of the amino acid sequence of the full-length polypeptide, excluding the N-terminal methionine residue, encoded by the cDNA contained in ATCC™

    Deposit Number 75927; and

    (i) a protein whose sequence consists of the amino acid sequence of the extracellular domain of the polypeptide encoded by the cDNA contained in ATCC™

    Deposit Number 75927.

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