Barb configurations for barbed sutures

• US 8,100,940 B2
• Filed: 09/30/2002
• Issued: 01/24/2012
• Est. Priority Date: 09/30/2002
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Quill Medical, Inc. (Angiotech Pharmaceuticals Incorporated)
• Inventors: Leung, Jeffrey C., Ruff, Gregory L., Megaro, Matthew A.
• Primary Examiner(s): NGUYEN, TUAN VAN
• Application Number:
  US10/065,279
• Publication Number:
  US 20040060409A1
• Time in Patent Office: 3,403 Days
• Field of Search: 606139-152, 606222-232, 244/47, 244/49
• US Class Current: 606/228
• CPC Class Codes: A61B 17/04 for suturing wounds; Holders or packages for needles or suture materials suture materials A61L17/00
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/06028 by means of a cylindrical longitudinal blind bore machined at the suture-receiving end of the needle, e.g. opposite to needle tip
• CPC Class Codes: A61B 2017/06057 Double-armed sutures, i.e. sutures having a needle attached to each end
• CPC Class Codes: A61B 2017/06176 with protrusions, e.g. barbs
• CPC Class Codes: A61L 17/04 Non-resorbable materials
• CPC Class Codes: A61L 17/12 Homopolymers or copolymers of glycolic acid or lactic acid
• CPC Class Codes: B26D 3/08 Making a superficial cut in the surface of the work without removal of material, e.g. scoring, incising
• CPC Class Codes: Y10T 83/852 Responsive to force

Abstract

A barbed suture for connecting tissue, and a combination surgical needle with a barbed suture. The suture includes an elongated body and a plurality of barbs projecting from the body. Each barb causes the suture to resist movement in an opposite direction from which the barb faces. The disposition of the barbs on the body may be staggered, twist cut multiple spiral, overlapping, or random. Also, the configuration of the barbs may be a certain spirality angle α, barb cut angle Θ, barb cut depth, barb cut length, barb cut distance, corrugated barb underside, arcuate barb base, or varying barb size.

Claims

1. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, and a second end (b) a plurality of barbs projecting from the body each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb faces, wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate, and a barb cut angle Θ

ranging from about 140 degrees to about 175 degrees.

2. The barbed suture according to claim 1, wherein the barb cut angle Θ

ranges from about 152 degrees to about 165 degrees.

3. The barbed suture according to claim 2, wherein the elongated body has a circular cross section.

4. The barbed suture according to claim 2, wherein the elongated body has a non-circular cross section.

5. The barbed suture according to claim 4, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

6. The barbed suture according to claim 2, wherein the barb cut angle Θ

ranges from about 152 degrees to about 163 degrees.

7. The barbed suture according to claim 6, wherein the elongated body has a circular cross section.

8. The barbed suture according to claim 6, wherein the elongated body has a non-circular cross section.

9. The barbed suture according to claim 8, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

10. The barbed suture according to claim 1, wherein the barbs are configured in at least two sets, each set having a barb size different from the barb size of the other set.

11. The barbed suture according to claim 1, wherein the suture is made from a material selected from the group consisting of a bio-absorbable material, a non-absorbable material, and combinations thereof.

12. The barbed suture according to claim 11, wherein the suture is made from a bio-absorbable material selected from the group consisting of polydioxanone, polylactide, polyglycolide, polycaprolactone, and combinations thereof.

13. The barbed suture according to claim 11, wherein the suture is made from a non-absorbable material selected from the group consisting of a polymer, a metal, a metal alloy, a natural fiber, and combinations thereof.

14. The barbed suture according to claim 13, wherein the polymer is selected from the group consisting of polyamide, polyester, polypropylene, polyurethane, polytetrafluoroethylene, polyether-ester, and combinations thereof.

15. The barbed suture according to claim 1, wherein the barbs have a disposition on the body selected from the group consisting of a staggered disposition, a twist cut multiple spiral disposition, an overlapping disposition, a random disposition, and combinations thereof.

16. The barbed suture according to claim 1, wherein the elongated body has a circular cross section.

17. The barbed suture according to claim 1, wherein the elongated body has a non-circular cross section.

18. The barbed suture according to claim 17, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

19. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, and a second end and a diameter and (b) a plurality of barbs projecting from the body, each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb faces, wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate, and a barb cut depth with a ratio of the barb cut depth to the suture diameter ranging from about 0.05 to about 0.6.

20. The barbed suture according to claim 19, wherein the ratio of the barb cut depth to the suture diameter ranges from about 0.3 to about 0.55.

21. The barbed suture according to claim 20, wherein the elongated body has a circular cross section.

22. The barbed suture according to claim 20, wherein the elongated body has a non-circular cross section.

23. The barbed suture according to claim 22, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

24. The barbed suture according to claim 20, wherein the ratio of the barb cut depth to the suture diameter ranges from about 0.4 to about 0.5.

25. The barbed suture according to claim 24, wherein the elongated body has a circular cross section.

26. The barbed suture according to claim 24, wherein the elongated body has a non-circular cross section.

27. The barbed suture according to claim 26, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

28. The barbed suture according to claim 19, wherein the barbs are configured in at least two sets, each set having a barb size different from the barb size of the other set.

29. The barbed suture according to claim 19, wherein the suture is made from a material selected from the group consisting of a bio-absorbable material, a non-absorbable material, and combinations thereof.

30. The barbed suture according to claim 29, wherein the suture is made from a bio-absorbable material selected from the group consisting of polydioxanone, polylactide, polyglycolide, polycaprolactone, and combinations thereof.

31. The barbed suture according to claim 29, wherein the suture is made from a non-absorbable material selected from the group consisting of a polymer, a metal, a metal alloy, a natural fiber, and combinations thereof.

32. The barbed suture according to claim 31, wherein the polymer is selected from the group consisting of polyamide, polyester, polypropylene, polyurethane, polytetrafluoroethylene, polyether-ester, and combinations thereof.

33. The barbed suture according to claim 19, wherein the barbs have a disposition on the body selected from the group consisting of a staggered disposition, a twist cut multiple spiral disposition, an overlapping disposition, a random disposition, and combinations thereof.

34. The barbed suture according to claim 19, wherein the elongated body has a circular cross section.

35. The barbed suture according to claim 19, wherein the elongated body has a non-circular cross section.

36. The barbed suture according to claim 35, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

37. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, and a second end and a diameter and (b) a plurality of barbs projecting from the body, each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb faces, wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate, and a barb cut length with a ratio of the barb cut length to the suture diameter ranging from about 0.2 to about 2.

38. The barbed suture according to claim 37, wherein the ratio of the barb cut length to the suture diameter ranges from about 0.4 to about 1.7.

39. The barbed suture according to claim 38, wherein the elongated body has a circular cross section.

40. The barbed suture according to claim 38, wherein the elongated body has a non-circular cross section.

41. The barbed suture according to claim 40, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

42. The barbed suture according to claim 38, wherein the ratio of the barb cut length to the suture diameter ranges from about 0.8 to about 1.5.

43. The barbed suture according to claim 42, wherein the elongated body has a circular cross section.

44. The barbed suture according to claim 42, wherein the elongated body has a non-circular cross section.

45. The barbed suture according to claim 44, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

46. The barbed suture according to claim 37, wherein the barbs are configured in at least two sets, each set having a barb size different from the barb size of the other set.

47. The barbed suture according to claim 37, wherein the suture is made from a material selected from the group consisting of a bio-absorbable material, a non-absorbable material, and combinations thereof.

48. The barbed suture according to claim 47, wherein the suture is made from a bio-absorbable material selected from the group consisting of polydioxanone, polylactide, polyglycolide, polycaprolactone, and combinations thereof.

49. The barbed suture according to claim 47, wherein the suture is made from non-absorbable material selected from the group consisting of a polymer, a metal, a metal alloy, a natural fiber, and combinations thereof.

50. The barbed suture according to claim 49, wherein the polymer is selected from the group consisting of polyamide, polyester, polypropylene, polyurethane, polytetrafluoroethylene, polyether-ester, and combinations thereof.

51. The barbed suture according to claim 37, wherein the barbs have a disposition on the body selected from the group consisting of a staggered disposition, a twist cut multiple spiral disposition, an overlapping disposition, a random disposition, and combinations thereof.

52. The barbed suture according to claim 37, wherein the elongated body has a circular cross section.

53. The barbed suture according to claim 37, wherein the elongated body has a non-circular cross section.

54. The barbed suture according to claim 53, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

55. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, and a second end and a diameter and (b) a plurality of barbs projecting from the body, each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb faces, wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate, and a barb cut distance with a ratio of the barb cut distance to the suture diameter ranging from about 0.1 to about 6.

56. The barbed suture according to claim 55, wherein the ratio of the barb cut distance to the suture diameter ranges from about 1 to about 3.5.

57. The barbed suture according to claim 56, wherein the elongated body has a circular cross section.

58. The barbed suture according to claim 56, wherein the elongated body has a non-circular cross section.

59. The barbed suture according to claim 58, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

60. The barbed suture according to claim 56, wherein the ratio of the barb cut distance to the suture diameter ranges from about 1.5 to about 2.5.

61. The barbed suture according to claim 60, wherein the elongated body has a circular cross section.

62. The barbed suture according to claim 60, wherein the elongated body has a non-circular cross section.

63. The barbed suture according to claim 62, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

64. The barbed suture according to claim 55, wherein the barbs are configured in at least two sets, each set having a barb size different from the barb size of the other set.

65. The barbed suture according to claim 55, wherein the suture is made from a material selected from the group consisting of a bio-absorbable material, a non-absorbable material, and combinations thereof.

66. The barbed suture according to claim 65, wherein the suture is made from a bio-absorbable material selected from the group consisting of polydioxanone, polylactide, polyglycolide, polycaprolactone, and combinations thereof.

67. The barbed suture according to claim 65, wherein the suture is made from a non-absorbable material selected from the group consisting of a polymer, a metal, a metal alloy, a natural fiber, and combinations thereof.

68. The barbed suture according to claim 67, wherein the polymer is selected from the group consisting of polyamide, polyester, polypropylene, polyurethane, polytetrafluoroethylene, polyether-ester, and combinations thereof.

69. The barbed suture according to claim 55, wherein the barbs have a disposition on the body selected from the group consisting of a staggered disposition, a twist cut multiple spiral disposition, an overlapping disposition, a random disposition, and combinations thereof.

70. The barbed suture according to claim 55, wherein the elongated body has a circular cross section.

71. The barbed suture according to claim 55, wherein the elongated body has a non-circular cross section.

72. The barbed suture according to claim 71, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

73. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, a second end and a diameter and (b) a plurality of barbs projecting from the body, each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb faces, wherein the barbs have (i) a barb cut Θ

angle ranging from about 140°

to about 175°

, (ii) a barb cut depth where the ratio of the barb cut depth to the suture diameter ranges from about 0.05 to about 0.6, (iii) a barb cut length where the ratio of the barb cut length to the suture diameter ranges from about 0.2 to about 2, and (iv) a barb cut distance where the ratio of the barb cut distance to the suture diameter ranges from about 0.1 to about 6 and (v) wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate.

74. The barbed suture according to claim 73, wherein the elongated body has a circular cross section.

75. The barbed suture according to claim 73, wherein the elongated body has a non-circular cross section.

76. The barbed suture according to claim 75, wherein the non-circular cross section has a shape selected from the group consisting of oval, triangle, square, parallepiped, trapezoid, rhomboid, pentagon, hexagon, cruciform, and combinations thereof.

77. A barbed suture for connecting human or animal tissue, said suture comprising (a) an elongated body having a longitudinal axis, a first end, a second end and a diameter and (b) a plurality of barbs projecting from the body, each barb facing in a direction and being adapted for resisting movement of the suture, when in tissue, in an opposite direction from the direction in which the barb jut depth where the ratio of the barb cut depth to the suture diameter ranges from about 0.05 to about 0.6, (iii) a barb cut length where the ratio of the barb cut length to the suture diameter ranges from about 0.2 to about 2, (iv) a barb cut distance where the ratio of the barb cut distance to the suture diameter ranges from about 0.1 to about 6, and (v) a twist cut multiple spiral disposition with a spirality angle α

ranging from about 5°

to about 25°

, and wherein the barbs have an underside, and the underside of the barb attaches to the suture body along a line that is transverse to the longitudinal axis of the elongated body and is concave arcuate.