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Calibration system for use with lateral flow assay test strips

  • US 8,101,415 B2
  • Filed: 07/05/2005
  • Issued: 01/24/2012
  • Est. Priority Date: 07/05/2005
  • Status: Expired due to Fees
First Claim
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1. A method of adjusting a final reflectance signal value measured on a lateral flow assay test strip, comprising:

  • measuring a series of reflectance signal values at a test site while performing a lateral flow assay reaction on a test strip;

    determining an extreme reflectance signal value representing the minimum reflectance signal value at the test site;

    determining an interim reflectance signal value, wherein the interim reflectance signal value is measured at the test site a pre-determined time period after the extreme reflectance signal value is measured;

    determining a final reflectance signal value at the test site after the interim reflectance signal value is determined;

    pre-determining a relationship between the interim reflectance signal value and the final reflectance signal value for the manufacturing lot from which the test strip has been made;

    adjusting the final reflectance signal value based upon the interim reflectance signal value and the pre-determined relationship between the interim reflectance signal value and the final reflectance signal value for the manufacturing lot from which the test strip has been made;

    wherein the step of adjusting the final reflectance signal value is conducted after the step of determining a final reflectance signal value.

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