Osmotic devices and methods for diuretic therapy
First Claim
1. An implantable occlusive device comprising:
- a wall member defining an enclosed volume, the wall member comprising a semi-permeable membrane;
a solution comprising a solvent and a solute, the solution disposed within the enclosed volume; and
a positioning member, the positioning member configured to maintain the position of the implantable occlusive device relative to a lengthwise axis of a lymphatic vessel;
the semi-permeable membrane permeable to the solvent and impermeable to the solute;
the enclosed volume configured to expand in response to decreases in osmolality of a bodily fluid and contract in response to increases in osmolality of a bodily fluid;
wherein the wall member and enclosed volume are configured to be fully implanted within a patient.
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Accused Products
Abstract
Embodiments of the invention are related to devices and methods for modulating renal function, amongst other things. In an embodiment, the invention includes an implantable occlusive device including a wall member defining an enclosed volume, the wall member can include a semi-permeable membrane. The device can also include a solution comprising a solvent and a solute disposed within the enclosed volume of the wall member. The semi-permeable membrane can be permeable to the solvent and impermeable to the solute. The enclosed volume can be configured to expand and contract in response to changes in the osmolality of a bodily fluid. The device can include a positioning member configured to maintain the position of the implantable occlusive device relative to a lengthwise axis of a lymphatic vessel. In an embodiment, the invention includes a method of modulating renal function in a patient including implanting an occlusive device in the patient, the occlusive device comprising a semi-permeable membrane and configured to expand or contract based on the passage of a fluid across the semi-permeable membrane. Other aspects and embodiments are provided herein.
16 Citations
16 Claims
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1. An implantable occlusive device comprising:
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a wall member defining an enclosed volume, the wall member comprising a semi-permeable membrane; a solution comprising a solvent and a solute, the solution disposed within the enclosed volume; and a positioning member, the positioning member configured to maintain the position of the implantable occlusive device relative to a lengthwise axis of a lymphatic vessel; the semi-permeable membrane permeable to the solvent and impermeable to the solute; the enclosed volume configured to expand in response to decreases in osmolality of a bodily fluid and contract in response to increases in osmolality of a bodily fluid; wherein the wall member and enclosed volume are configured to be fully implanted within a patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification