Disposable dispenser for patient infusion

• US 8,105,280 B2
• Filed: 05/14/2006
• Issued: 01/31/2012
• Est. Priority Date: 05/17/2005
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Medingo Ltd. (Roche Holding AG)
• Inventors: Iddan, Gavriel J., Friedman, Avishai, Yodfat, Ofer
• Primary Examiner(s): Desanto, Matthew F
• Application Number:
  US11/920,469
• Publication Number:
  US 20080234630A1
• Time in Patent Office: 2,088 Days
• Field of Search: 604131-155, 604/890.1, 604/891.1, 604/892.1, 604/181, 604/187
• US Class Current: 604/131
• CPC Class Codes: A61M 2205/0244 Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 5/003 Kits for diabetics
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/14236 Screw, impeller or centrifugal type pumps
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/422 Desensitising skin

Abstract

Embodiments of the invention are directed to methods and systems associated with a disposable dispenser (100, 200) of therapeutic fluid. Preferred embodiments having a small size of less than about 75 mm in length, less than 50 mm in width and less than about 10 mm in thickness and may be releasably attached to the body (B). In one embodiments, the dispenser draws fluid from a flexible volume-conformable reservoir (4) and operates a dosing and metering pump (6, 61, 62, 63) incorporating a motor to deliver fluid through a fluid delivery tool (8, 81, 82). Disposed on the housing bottom (2B) is a peel-off tape (22) that when removed, electrically connects a power supply (18) to power the operative components (3) of the dispenser into operation, exposes an adhesive (28) and a window (21) in the housing (2), and allows the fluid delivery tool (8) to extend for insertion into the skin (S).

Claims

1. A disposable therapeutic fluid dispenser having a thin flat planar construction for infusing a therapeutic fluid through the skin into the body of a user, the dispenser comprising:

a housing;

a power supply;

a reservoir;

a pump;

a window provided on a first side of the housing;

a fluid delivery tool, the fluid delivery tool being fluidly coupled to the pump and being insertable through the window into the body of the user to deliver one or more controlled doses of therapeutic fluid to the user; and

removable tape arranged on the first side of the housing and configured upon removal to;

expose the window for insertion of the fluid delivery tool therethrough into the body of the user; and

enable the supply of power for operation of the fluid dispenser.

2. The disposable therapeutic fluid dispenser according to claim 1, wherein

said pump is a peristaltic pump arranged within an interior of the housing, the peristaltic pump comprising a motor and a gear, and

a counter plate provided on a second side of a fluid delivery tube opposite a first side of the fluid delivery tube which is positioned adjacent to the gear.

3. The disposable therapeutic fluid dispenser according to claim 2, wherein the peristaltic pump is a single gear pump.

4. The disposable therapeutic fluid dispenser according to claim 2, further comprising a gear position sensor disposed within the housing interior in operative association with the pump, and coupled to the controller to derive the flow rate of the therapeutic fluid.

5. The disposable therapeutic fluid dispenser according to claim 2, further comprising at least two pressure sensors disposed within the housing interior said sensors are spatially arranged downstream of the pump and upstream of the fluid delivery tool, and said sensors are coupled to the controller to derive either one of fluid flow rate and fluid flow pressure or both fluid flow rate and fluid flow pressure.

6. The disposable therapeutic fluid dispenser according to claim 1, wherein:

the pump has at least one gear with distributed therein a plurality of magnetic rotors, a plurality of electric drive coils distributed within the housing interior in accordance with the plurality of magnetic rotors, wherein the electric drive coils are controllable by the controller to rotate the at least one gear.

7. The disposable therapeutic fluid dispenser according to claim 6, wherein the electric drive coils are controllable by the controller to rotate the single gear at a pre-determined speed of rotation;

and the dose supplied by the pump is predetermined according to the configuration of the gear and of the speed of rotation of the gear.

8. The disposable therapeutic fluid dispenser according to claim 6, further comprising a gear position sensor disposed within the housing interior in operative association with the pump, and said sensor is coupled to the controller to derive the flow rate of the therapeutic fluid.

9. The disposable therapeutic fluid dispenser according to claim 6, further comprising at least two pressure sensors said sensors are disposed within the housing interior spatially arranged downstream of the pump and upstream of the fluid delivery tool, and said sensors are coupled to the controller to derive either one of fluid flow rate and fluid flow pressure or both fluid flow rate and fluid flow pressure.

10. The disposable therapeutic fluid dispenser according to claim 1, wherein said pump is a gear-on-gear pump.

11. The disposable therapeutic fluid dispenser according to claim 10, further comprising a gear position sensor disposed within the housing interior in operative association with the pump, and said sensor is coupled to the controller to derive the flow rate of the therapeutic fluid.

12. The disposable therapeutic fluid dispenser according to claim 10, further comprising at least two pressure sensors said sensors are disposed within the housing interior spatially arranged downstream of the pump and upstream of a fluid delivery tool, and said sensors coupled to the controller to derive either one of fluid flow rate and fluid flow pressure or both fluid flow rate and fluid flow pressure.

13. The disposable therapeutic fluid dispenser according to claim 1, wherein said pump is electromagnetic membrane pump.

14. The disposable therapeutic fluid dispenser according to claim 13, further comprising at least two pressure sensors disposed within the housing interior said sensors are spatially arranged downstream of the pump and upstream of a fluid delivery tool, and said sensors are coupled to the controller to derive either one of fluid flow rate and fluid flow pressure or both fluid flow rate and fluid flow pressure.

15. The disposable therapeutic fluid dispenser according to claim 1, wherein the fluid delivery tool is capable of being arranged in a collapsed position upon being placed in a package, and wherein upon removing the dispenser from the package, the fluid delivery tool is capable of unfolding to protrude to the housing exterior and thereby be ready for insertion into the body of the user.

16. The disposable therapeutic fluid dispenser according to claim 15, wherein the fluid delivery tool is capable of being re-collapsed for placement into a package for disposal.

17. The disposable therapeutic fluid dispenser according to claim 1, further comprising a controller for at least one of control, management and operation of the dispenser wherein upon removal of the tape, power is supplied to at least one of the controller and the pump to enable operation of the fluid dispenser.

18. A method for operating a disposable therapeutic fluid dispenser having a thin flat planar construction for infusing a therapeutic fluid through the skin into the body of a user, comprising:

providing a therapeutic fluid dispenser, the fluid dispenser comprising;

a housing;

a power supply;

a reservoir;

a pump;

a window provided on a first side of the housing;

a fluid delivery tool, the fluid delivery tool being fluidly coupled to the pump and being insertable through the window into the body of the user to deliver one or more controlled doses of the therapeutic fluid; and

a removable tape arranged on the first side of the housing; and

exposing the window for insertion of the fluid delivery tool therethrough into the body of the user by removing the tape, wherein removal of the tape also results in power being supplied for operation of the fluid dispenser.

19. The method according to claim 18, wherein the fluid dispenser further comprises a controller for at least one of control, management and operation of the dispenser, and wherein upon removal of the tape, power is supplied from the power supply to at least one of the pump and controller to enable operation of the fluid dispenser.